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Performance comparison between MRI and CT for local staging of sigmoid and descending colon cancer.
European Journal of Radiology ( IF 3.2 ) Pub Date : 2019-11-20 , DOI: 10.1016/j.ejrad.2019.108741
Li-Heng Liu 1 , Han Lv 2 , Zhen-Chang Wang 2 , Sheng-Xiang Rao 1 , Meng-Su Zeng 1
Affiliation  

PURPOSE To compare the diagnostic performance of MRI and CT for local staging of sigmoid and descending colon cancer, with pathological results as the reference standard. METHOD This retrospective study included 116 patients with sigmoid or descending colon cancer who underwent both MRI and CT before surgery. MRI and CT images were separately reviewed by two independent and blinded radiologists to assess the following features: T-stage, presence of extramural extension (T3-4 disease), lymph node metastases (N+), and extramural vascular invasion (EMVI+). Diagnostic performance with sensitivity and specificity for detecting positive status (T3-4, N+ or EMVI+) were assessed using receiver-operating-characteristic (ROC) curve, and compared between MRI and CT. RESULTS MRI achieved correct T-stage in 81 of 116 patients (69.8 %) while CT in 66 (56.9 %). For detecting T3-4 disease, MRI showed better performance than CT with area under the curve (AUC) of 0.888 versus 0.712 (P =  0.002) and specificity of 81.82 % versus 54.6 % (P =  0.011). No significance was found in sensitivity between two modalities (89.2 % versus 83.1 %, P =  0.302). For detecting N+ disease, performance of MRI and CT were similar (AUC, 0.670 versus 0.650, P =  0.412). For detecting EMVI+, MRI showed better performance than CT (AUC, 0.780 versus 0.575, P =  0.012) with significantly higher sensitivity (68.6 % versus 40.0 %, P =  0.031) and similar specificity (both are 84.3 %). CONCLUSIONS MRI may offer more superior diagnostic performance than CT for detecting T3-4 disease and EMVI, thereby supporting its alternative application to CT in local staging of colon cancer.

中文翻译:

MRI和CT对乙状结肠癌和降结肠癌的局部分期的性能比较。

目的比较MRI和CT对乙状结肠癌和降结肠癌的局部分期的诊断性能,以病理结果为参考标准。方法这项回顾性研究包括116例乙状结肠或降结肠癌患者,他们在手术前均接受了MRI和CT检查。两名独立且不知情的放射线医师分别对MRI和CT图像进行了评估,以评估以下特征:T期,壁外延伸的存在(T3-4疾病),淋巴结转移(N +)和壁外血管浸润(EMVI +)。使用接收者操作特征(ROC)曲线评估诊断性能的敏感性和特异性,以检测阳性状态(T3-4,N +或EMVI +),并在MRI和CT之间进行比较。结果MRI在116例患者中有81例(69.8%)达到了正确的T期,而CT在66例(56.9%)中达到了正确的T期。对于检测T3-4疾病,MRI的表现优于CT,曲线下面积(AUC)为0.888对0.712(P = 0.002),特异性为81.82%对54.6%(P = 0.011)。在两种模态之间的灵敏度上均未发现显着性(89.2%对83.1%,P = 0.302)。为了检测N +疾病,MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。MRI表现出比CT更好的性能,曲线下面积(AUC)为0.888对0.712(P = 0.002),特异性为81.82%对54.6%(P = 0.011)。在两种模态之间的灵敏度上均未发现显着性(89.2%对83.1%,P = 0.302)。为了检测N +疾病,MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。MRI表现出比CT更好的性能,曲线下面积(AUC)为0.888对0.712(P = 0.002),特异性为81.82%对54.6%(P = 0.011)。在两种模态之间的灵敏度上均未发现显着性(89.2%对83.1%,P = 0.302)。为了检测N +疾病,MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。002)和特异性为81.82%对54.6%(P = 0.011)。在两种模态之间的灵敏度上均未发现显着性(89.2%对83.1%,P = 0.302)。为了检测N +疾病,MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。002)和特异性为81.82%对54.6%(P = 0.011)。在两种模态之间的灵敏度上均未发现显着性(89.2%对83.1%,P = 0.302)。为了检测N +疾病,MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。MRI和CT的表现相似(AUC,0.670对0.650,P = 0.412)。在检测EMVI +方面,MRI表现出比CT更好的性能(AUC,0.780对0.575,P = 0.012),灵敏度(68.6%对40.0%,P = 0.031)显着更高,并且特异性相似(均为84.3%)。结论MRI在检测T3-4疾病和EMVI方面可能比CT提供更好的诊断性能,从而支持其在结肠癌局部分期中CT的替代应用。
更新日期:2019-11-01
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