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Progress in the Mechanism and Clinical Application of Cilostazol.
Current Topics in Medicinal Chemistry ( IF 2.9 ) Pub Date : 2019-01-01 , DOI: 10.2174/1568026619666191122123855
Huilei Zheng 1, 2, 3 , Hua Yang 2, 3, 4 , Danping Gong 2, 3, 5 , Lanxian Mai 2, 3, 6 , Xiaoling Qiu 2, 3 , Lidai Chen 2, 3 , Xiaozhou Su 2, 3 , Ruoqi Wei 7 , Zhiyu Zeng 2, 3, 5
Affiliation  

Cilostazol is a unique platelet inhibitor that has been used clinically for more than 20 years. As a phosphodiesterase type III inhibitor, cilostazol is capable of reversible inhibition of platelet aggregation and vasodilation, has antiproliferative effects, and is widely used in the treatment of peripheral arterial disease, cerebrovascular disease, percutaneous coronary intervention, etc. This article briefly reviews the pharmacological mechanisms and clinical application of cilostazol.

中文翻译:

西洛他唑的作用机理和临床应用进展。

西洛他唑是一种独特的血小板抑制剂,已在临床上使用了20多年。西洛他唑是一种磷酸二酯酶III型抑制剂,具有可逆性抑制血小板聚集和血管舒张的作用,具有抗增殖作用,被广泛用于治疗外周动脉疾病,脑血管疾病,经皮冠状动脉介入治疗等。西洛他唑的作用机理和临床应用。
更新日期:2019-11-01
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