Cluster headache stands among the worst debilitating pain conditions. Available treatments for cluster headache have often disabling side effects, are not tolerated, or are ineffective. The management of drug-refractory chronic forms is challenging. New treatments are warranted and reported here.

中文翻译：

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新兴的丛集性头痛治疗方法：希望和失望。

丛集性头痛是使人衰弱最严重的疼痛之一。现有的治疗丛集性头痛的方法通常会导致副作用，无法忍受或无效。药物难治性慢性病的治疗具有挑战性。有必要进行新的治疗并在此处报告。