Diastolic dysfunction is primarily an echocardiographic diagnosis. Its clinical counterpart is diastolic heart failure, where the heart has difficulty to fill at normal pressure and the patient develops signs of pulmonary edema. Although diastolic dysfunction is common in adults, limited information is available in preterm infants. The aim of this study is to explore left ventricular diastolic dysfunction and diastolic heart failure in preterm infants and describe clinical manifestations in this population. This is a retrospective observational study in preterm infants < 30 weeks' gestation who received an echocardiography in the first 4 weeks after birth. Diastolic dysfunction was graded using a population-specific adapted version of the adult recommendations for the evaluation of left ventricular diastolic function by echocardiography. Left ventricular diastolic dysfunction was absent, indeterminate, and definite in 82%, 14%, and 4% of the 168 echocardiograms analyzed, and is associated with increased respiratory signs and respiratory deterioration at 48 h before echocardiogram. In seven infants, diastolic heart failure was diagnosed with both ultrasound and clinical signs. The cumulative risk of diastolic dysfunction increased with the increasing postnatal age and a patent ductus arteriosus. Evidence of left ventricular diastolic dysfunction on echocardiography is relatively common in preterm infants, while the left ventricular diastolic heart failure is less frequent. Prolonged exposure to volume load was the most common cause.

中文翻译：

---

早产儿左心室舒张功能不全和舒张性心力衰竭。

舒张功能障碍主要是超声心动图诊断。其临床对应物是舒张性心力衰竭，其中心脏在正常压力下难以充盈，并且患者出现肺水肿的迹象。尽管舒张功能障碍在成年人中很常见，但早产儿的信息有限。这项研究的目的是探讨早产儿左心室舒张功能障碍和舒张性心力衰竭，并描述该人群的临床表现。这是一项回顾性观察性研究，研究对象是胎龄小于30周的早产儿，出生后前4周接受了超声心动图检查。使用针对成年人的特定人群适应版本对成人舒张功能障碍进行分级，以通过超声心动图评估左心室舒张功能。在分析的168例超声心动图中，左心室舒张功能障碍不存在，不确定，确定，分别为82％，14％和4％，并且与超声心动图前48 h呼吸信号增加和呼吸恶化有关。在7例婴儿中，超声和临床体征均诊断为舒张性心力衰竭。舒张功能障碍的累积风险随着出生年龄的增加和动脉导管未闭的增加而增加。超声心动图上左心室舒张功能障碍的证据在早产儿中相对普遍，而左心室舒张性心力衰竭的发生频率较低。长时间暴露于体积负荷是最常见的原因。并在超声心动图检查前48小时与呼吸道症状增加和呼吸系统恶化相关。在7例婴儿中，超声和临床体征均诊断为舒张性心力衰竭。舒张功能障碍的累积风险随着出生年龄的增加和动脉导管未闭的增加而增加。超声心动图上左心室舒张功能障碍的证据在早产儿中相对普遍，而左心室舒张性心力衰竭的发生频率较低。长时间暴露于体积负荷是最常见的原因。并在超声心动图检查前48 h与呼吸道症状增加和呼吸系统恶化相关。在7例婴儿中，超声和临床体征均诊断为舒张性心力衰竭。舒张功能障碍的累积风险随着出生年龄的增加和动脉导管未闭的增加而增加。超声心动图上左心室舒张功能障碍的证据在早产儿中相对普遍，而左心室舒张性心力衰竭的发生频率较低。长时间暴露于体积负荷是最常见的原因。舒张功能障碍的累积风险随着出生年龄的增加和动脉导管未闭的增加而增加。超声心动图上左心室舒张功能障碍的证据在早产儿中相对普遍，而左心室舒张性心力衰竭的发生频率较低。长时间暴露于体积负荷是最常见的原因。舒张功能障碍的累积风险随着出生年龄的增加和动脉导管未闭的增加而增加。超声心动图上左心室舒张功能障碍的证据在早产儿中相对普遍，而左心室舒张性心力衰竭的发生频率较低。长时间暴露于体积负荷是最常见的原因。