The ethanol extract of the leaves of Tabernaemontana divaricata (double flower variety) provided a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, voafinine, N-methylvoafinine, voafinidine, voalenine and the new bisindole alkaloid, conophyllinine in addition to the previously known, biologically active bisindole, conophylline and its congener, conofoline. The structures of the new alkaloids were established by spectroscopic methods. The preparation and characterization of the corresponding quinones of the biologically active bisindoles are also described in relation to a structure-activity study of these compounds with respect to their action in stimulating insulin expression.

中文翻译：

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泰伯油菜（Tabernaemontana divaricata）的生物活性吲哚和双吲哚生物碱。

大叶藤叶（双花植物）叶片的乙醇提取物提供了总共23种生物碱，除了以前的以前，还包括新的曲霉属生物碱，塔伯汉宁，伏安芬宁，N-甲基伏安芬宁，伏安芬定，voalenine和新的双吲哚生物碱，花碱碱已知的具有生物活性的双吲哚，茶碱及其同类物，conooline。通过光谱学方法确定了新生物碱的结构。还就这些化合物在刺激胰岛素表达方面的作用进行了结构活性研究，对生物活性双吲哚的相应醌的制备和表征进行了描述。