Attempts have been made to observe the tissue repair of neo-esophagus after esophageal muscularis resection and to investigate possibility of the regeneration repair of esophageal muscularis resection in neo-esophagus. Sixteen pigs were divided into two groups: group A and group B. Pigs in group A were performed with the partial resection of mere esophageal muscularis propria reserved mucosa muscle layer in a segment of thoracic esophagus. Pigs in group B were performed with nitinol composite artificial esophagus with polyester sewing rings replacement a segment of thoracic esophagus resection. Pigs in the two groups were performed with euthanasia at the following times: 2, 4, 6, and 12 months for postmortem analysis, which demonstrated the absence of esophageal muscularis regeneration in the specimens that were sampled from different time points. Reserved mucosa muscle layer did not show hyperplasia to repair coloboma of esophageal muscularis propria deletion in group A. These results suggest that after esophageal muscularis resection, including mucosa muscle layer or esophageal muscularis propria, the coloboma of esophageal muscularis was repaired with connective tissue filling quickly. It would be very difficult for the regeneration repair of esophageal muscularis in neo-esophageal tissue structure after esophageal muscularis resection.

中文翻译：

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食管肌瘤切除术后新食管组织修复的实验研究。

曾尝试观察食管肌瘤切除后新食管的组织修复，并研究了新食道食管肌瘤切除的再生修复的可能性。将16只猪分为两组：A组和B组。A组中的猪在胸段食道中仅切除部分食道固有肌固有层保留的粘膜肌肉层。B组的猪用镍钛合金复合人工食道进行手术，用聚酯缝合环代替一部分胸腔食管切除术。两组猪在以下时间进行安乐死：2、4、6和12个月进行死后分析，这表明从不同时间点采集的标本中不存在食道肌瘤再生。保留的粘膜肌层未显示增生以修复A组食管肌固有层缺失。这些结果表明，在食管肌瘤切除后，包括粘膜肌层或食管肌固有层在内，食管肌层间质瘤可通过结缔组织填充快速修复。 。食管肌瘤切除后，新食管组织结构中食管肌瘤的再生修复将非常困难。