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E/a' ratio is closely related to pulmonary vein flow profile in patients with normal ejection fraction.
Scandinavian Cardiovascular Journal ( IF 1.2 ) Pub Date : 2019-08-02 , DOI: 10.1080/14017431.2019.1645348
Benny Johansson 1 , Fredrik Lundin 2 , Rolf Tegeback 3 , Leif Bojö 4
Affiliation  

Objectives. To compare the ability of the E/a′ ratio and the recommended diastolic parameters in the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI), in predicting a dominant diastolic pulmonary vein flow in patients with normal ejection fraction. Design. We retrospectively evaluated the diastolic function according to the ASE/EACVI guidelines, the S/D ratio and the septal, lateral and average E/a′ ratio in 293 unselected in-hospital patients, aged 39–86 years, in sinus rhythm and with no or mild valve disease, having a normal systolic function (EF > 50%). Results. The S/D ratio had a positive association to septal, lateral and average E/a ratio (R2 = 0.25, 0.35 and 0.32). The association to average E/e′ ratio, LA vol index and TR velocity was weak (R2 = 0.037, 0.033 and 0.087) and for e′ velocity negatively. In patients with S/D ratio <1, septal, lateral, average E/a′ ratio, average E/e ratio, LA vol index (p<.001) and TR velocity (p<.05) were significantly higher compared to patients with S/D ratio ≥1. No significant difference was seen in e′ velocity. The septal, lateral and average E/a′ ratio were significantly higher in patients with S/D ratio <1 regardless a normal or impaired diastolic function according to the ASE/EACVI guidelines (p<.001). The ASE/EACVI algorithm detected 21 patients with S/D ratio <1 compared to 28 patients using average E/a′ ratio with cut-off >14. Conclusion: E/a′ ratio might be a useful new diastolic parameter in patients with a normal ejection fraction as it is more closely related to the S/D ratio than the established ASE/EACVI diastolic parameters.



中文翻译:

E / a'比与射血分数正常的患者的肺静脉血流状况密切相关。

目标。为了比较E / a'比和美国超声心动图学会(ASE)和欧洲心血管影像协会(EACVI)推荐的舒张压参数在预测射血分数正常的患者中主要的舒张性肺静脉血流的能力。设计。我们根据ASE / EACVI指南,年龄在39-86岁,窦律性心律不齐的293例未入院住院患者的S / D比以及间隔,外侧和平均E / a'比,回顾性评估了舒张功能。无或轻度瓣膜疾病,具有正常的收缩功能(EF> 50%)。结果。S / D比与中隔,外侧和平均E / a比呈正相关(R 2= 0.25、0.35和0.32)。与平均E / e'比,LA体积指数和TR速度的关联较弱(R 2 = 0.037、0.033和0.087),而e'速度则为负。在S / D比<1的患者中,中隔,外侧,平均E / a'比,平均E / e比,LA容积指数(p <.001)和TR速度(p <.05)与S / D比≥1的患者。e'速度无明显差异。根据ASE / EACVI指南,无论舒张功能正常还是受损,S / D比率<1的患者的间隔,外侧和平均E / a'比率均显着更高(p<.001)。ASE / EACVI算法检测到21例S / D比率小于1的患者,而使用平均E / a'比率的28例患者的临界值大于14。结论 E / a'比可能是射血分数正常的患者有用的新舒张参数,因为它与S / D比的关系比已建立的ASE / EACVI舒张参数更密切。

更新日期:2019-08-02
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