甲醛可替代抗生素，用于治疗难治性脓疱病和其他传染性皮肤病。,Expert Review of Anti-infective Therapy

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甲醛可替代抗生素，用于治疗难治性脓疱病和其他传染性皮肤病。
Expert Review of Anti-infective Therapy ( IF 4.2 ) Pub Date : 2019-08-09 , DOI: 10.1080/14787210.2019.1654376
Philip Nikolic ₁ , Poonam Mudgil ₁ , John Whitehall ₁

Affiliation

简介：细菌的抗生素抗性菌株在医院和社区中正成为一个日益严重的问题。这导致细菌感染如脓疱疮变得难以治疗。需要其他治疗选择。涵盖的领域：本文描述了一项过去评估昆士兰州北部health疮健康负担的研究，并从中讨论了甲醛替代抗菌治疗的潜力。在此过程中，引入了抗生素抗药性，脓疱病，氯菊酯和甲醛，并概述了目前甲醛对人类影响的理解和局限性。还讨论了细菌对甲醛抵抗的有限情况。专家意见：甲醛由于其抗菌活性，目前被用作化妆品和药用霜剂的防腐剂。因此，它有可能被用作抗生素抗性细菌感染的另一种抗菌治疗方法。空气中甲醛的有害副作用和过敏性个体的暴露已得到广泛研究。关于健康个体中甲醛皮肤接触的研究很少。如果甲醛可安全用于人体局部用药，则它有潜力协助抵抗抗生素耐药性。关于健康个体中甲醛皮肤接触的研究很少。如果甲醛可安全用于人体局部用药，则它有潜力协助抵抗抗生素耐药性。关于健康个体中甲醛皮肤接触的研究很少。如果甲醛可安全用于人体局部用药，则它有潜力协助抵抗抗生素耐药性。

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Formaldehyde as an alternative to antibiotics for treatment of refractory impetigo and other infectious skin diseases.

Introduction: Antibiotic-resistant strains of bacteria are an increasing problem in hospitals and in the community. This has resulted in bacterial infections such as impetigo becoming difficult to treat. Alternative treatment options are needed. Areas covered: In this paper, a past study that assessed the health burden of scabies in North Queensland is described and from it, the potential for formaldehyde as an alternative antimicrobial treatment is discussed. In doing so, antibiotic resistance, impetigo, permethrin, and formaldehyde are introduced and the current understanding and limitations of the effects of formaldehyde on humans are outlined. The limited cases of formaldehyde resistance in bacteria are also discussed. Expert opinion: Formaldehyde is currently used as a preservative in cosmetics and medicinal creams due to its antibacterial activity. It, therefore, has the potential to be used as an alternative antibacterial treatment for infections with antibiotic-resistant bacteria. The harmful side effects of airborne formaldehyde and exposure in allergic individuals have been extensively studied. Significantly less research has been conducted on formaldehyde skin contact in healthy individuals. If formaldehyde is safe for topical use in humans, it has the potential to assist with combating antibiotic resistance.

更新日期：2019-11-01

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