OBJECTIVE To compare laparoscopic dissection with-laparoscopic dissection combined with abdominal instillation of ferric hyaluronate gel for the treatment of experimentally induced adhesions in pony foals. ANIMALS 12 healthy pony foals. PROCEDURE A serosal abrasion method was used to create adhesions at 4 sites on the jejunum (day 0). At day 7 laparoscopy was performed and the adhesions observed in each foal were recorded. In group-1 foals (n = 6), the adhesions were separated laparoscopically (treatment 1). In group-2 foals (n = 6), 300 mL of 0.5% ferric hyaluronate gel was infused into the abdomen after the adhesions were separated laparoscopically (treatment 2). At day 24, terminal laparoscopy was performed and the adhesions observed were recorded. Total number of adhesions within each group was compared between day 7 and 24. Data were analyzed to determine whether an association existed between the number of adhesions on day 24 and treatment type. RESULTS At day 24, the number of adhesions was significantly decreased within each group, compared with the number of adhesions at day 7 (group-1 foals, 10 vs 22 adhesions; group-2 foals, 3 vs 20 adhesions). Treatment 1 was associated with a significantly higher number of adhesions at day 24, compared with treatment 2 (odds ratio, 4.54; 95% confidence interval, 1.03 to 23.02). CONCLUSION AND CLINICAL RELEVANCE Abdominal instillation of 0.5% ferric hyaluronate gel after laparoscopic dissection was a more effective technique than laparoscopic dissection alone to treat experimentally induced adhesions in pony foals. Laparoscopic adhesiolysis following abdominal surgery in foals is a safe and effective technique.

中文翻译：

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两种腹腔镜治疗对小马驹腹部粘连的实验性比较。

目的比较腹腔镜清扫术与腹腔镜清扫术联合腹部滴注透明质酸铁凝胶治疗小马驹实验性粘连的疗效。动物12种健康的小马驹。程序浆膜磨蚀法用于在空肠的4个部位（第0天）产生粘连。在第7天，进行腹腔镜检查并记录在每个小马驹中观察到的粘连。在第1组小马驹（n = 6）中，腹腔镜下分离粘连（治疗1）。在第2组小马驹（n = 6）中，在腹腔镜下分离粘连后将300 mL 0.5％透明质酸铁凝胶注入腹部（治疗2）。在第24天，进行腹腔镜检查并记录观察到的粘连。在第7天和第24天之间比较各组内的粘连总数。分析数据以确定在第24天的粘连数与治疗类型之间是否存在关联。结果与第7天时的粘连数相比，第24天，每组的粘连数均显着减少（第1组小马驹，10 vs 22粘连；第2组小马驹，3对20粘连）。与治疗2相比，治疗1在第24天的粘附数量明显更高（几率4.54； 95％置信区间1.03至23.02）。结论和临床意义腹腔镜解剖后腹腔滴入0.5％透明质酸铁凝胶是一种比单独腹腔镜解剖更有效的技术，用于治疗小马驹的实验性粘连。小马驹腹部手术后的腹腔镜粘连溶解是一种安全有效的技术。