Abstract

Coumarin (2H-1-benzopyran-2-one) is a phenolic compound derived from the shikimate pathway and synthesized by various medicinal and aromatic plants as parent molecule of a large group of secondary metabolites, namely coumarins. Its main utilization is as fixative in perfumes and flavour enhancer. Given its role as phytoalexin and phagodepression activity, herein we evaluated for the first time its efficacy against several insect species: the green peach aphid, Myzus persicae, the moth Spodoptera littoralis, the housefly, Musca domestica and the filariasis vector Culex quinquefasciatus. Two non-target species were also included in our toxicity evaluation experiments: the ladybug Harmonia axyridis and the earthworm Eisenia fetida. Results highlighted remarkable selectivity of coumarin, being highly toxic to M. persicae aphids (LC₅₀₍₉₀₎ values of 1.3(1.9) mg L⁻¹) and friendly to natural enemies of aphids as well as soil invertebrates.

摘要

香豆素（2H-1-苯并吡喃-2-酮）是衍生自sh草酸酯途径的酚类化合物，由各种药用植物和芳香植物合成，作为一大批次级代谢物即香豆素的母体分子。它的主要用途是作为香水和增香剂中的固定剂。鉴于其作为植物抗毒素和吞噬抑制活性的作用，在此我们首次评估了其对几种昆虫物种的功效：绿色桃蚜，桃蚜，蛾蛾斜纹夜蛾，家蝇，家蝇和丝虫病载体库克西克斯菌。我们的毒性评估实验中还包括了两个非目标物种：瓢虫Harmonia axyridis还有E ise E（Eisenia fetida）。结果突出香豆素显着的选择性，是剧毒中号。桃蚜蚜虫（LC _50（90）的值1.3（1.9）毫克的L ^-1）和友好的蚜虫的天敌以及土壤无脊椎动物。