A lactose-containing fermentation medium initiated the formation of 7-O-beta-D-galactosyl-brefeldin A [1] in the brefeldin A-producing organism, Penicillium brefeldianum. The detection, isolation, and physicochemical properties of 1, which has been produced by biological derivatization via transglycosylation, are described. Compound 1 is the first glycosylated brefeldin A derivative to have been prepared.

中文翻译：

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通过化学筛选的次生代谢产物，通过不育青霉的转糖基化作用获得26.17-O-β-D-半乳糖基-布雷菲德菌素A。

含乳糖的发酵培养基在产生布雷菲德菌素A的有机体-布雷尼迪青霉中引发了7-O-β-D-半乳糖基-布雷菲德菌素A的形成[1]。描述了通过转糖基化的生物衍生作用产生的1的检测，分离和理化性质。化合物1是已制备的第一个糖基化布雷菲德菌素A衍生物。