Few studies have reported quantitative data about the levels of prenylated coumarins in Ferula sp. Yet, the toxicity of Ferula sp. is only due to the presence of prenylated coumarins and to their concentrations and all studies suggest the existence of several chemotypes within the same species or even within the same variety. The aim of this study was to investigate the hypothesis of different chemotypes in french Ferula sp. in relationship with the botanical species. In this objective, the species of giant fennels and their concentrations in prenylated coumarins were explored. Three different species or subspecies of giant fennel were detected in continental France: F. communis communis communis L., F. communis catalaunica microcarpa Cauwet-Marc and F. glauca L. Surprisingly, the three species/subspecies of giant fennels were found to be located in exclusive and well separated geographical areas. In French giant fennels, ferulenol and ferprenin were detected. Distribution of ferulenol and ferprenin were found to be different between botanical varieties, but also according to the season, the soil and the altitude. Our study seems to suggest that among F. communis species, the same plant can be regarded as poisonous at one point and another as non-poisonous.

中文翻译：

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法国大茴香叶（Ferula sp。）叶中阿魏烯醇和戊二烯浓度的变化。

很少有研究报告有关Ferula sp。中烯丙基香豆素水平的定量数据。然而，Ferula sp。的毒性。这仅是由于异戊烯化香豆素的存在及其浓度所致，所有研究均表明，同一物种内甚至同一品种内都存在几种化学型。这项研究的目的是调查法国Ferula sp。中不同化学型的假设。与植物种类有关。在这个目标中，探索了大茴香的种类及其在烯丙基香豆素中的浓度。在法国大陆上发现了三种不同的巨型茴香物种或亚种：F. communis communis communis L.，F. communis catalaunica microcarpa Cauwet-Marc和F. glauca L.令人惊讶的是，发现大型茴香的三个物种/亚种位于排他的且分隔良好的地理区域。在法国大茴香中，检出了阿魏烯醇和铁蛋白。发现植物品种中阿魏烯醇和铁蛋白的分布不同，但还取决于季节，土壤和海拔高度。我们的研究似乎表明，在F. communis物种中，同一植物在某一时刻可被视为有毒，而在另一地点则被视为无毒。