Three piperidine alkaloid containing plants, Conium maculatum (poison-hemlock), Nicotiana glauca (tree tobacco) and Lupinus formosus (lunara lupine), induced multiple congenital contractures (MCC) and palatoschisis in goat kids when their dams were gavaged with the plant during gestation days 30-60. The skeletal abnormalities included fixed extension or flexure of the carpal, tarsal, and fetlock joints, scoliosis, lordosis, torticollis and rib cage abnormalities. Clinical signs of toxicity included those reported in sheep, cattle and pigs--ataxia, incoordination, muscular weakness, prostration and death. One quinolizidine alkaloid containing plant, Lupinus caudatus (tailcup lupine), on the other hand, which is also known to cause MCC in cows, caused only slight signs of toxicity in pregnant goats and no teratogenic effects in their offspring.

中文翻译：

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山羊因摄入羽扇豆、圆锥花序和烟草而引起先天性骨骼畸形和腭裂。


三种含有哌啶生物碱的植物，毒铁杉、烟草和羽扇豆，当母羊在妊娠期间用该植物灌胃时，会引起山羊幼崽的多发性先天性挛缩 (MCC) 和腭裂第 30-60 天。骨骼异常包括腕关节、跗关节和球节关节的固定伸展或弯曲、脊柱侧凸、脊柱前凸、斜颈和胸腔异常。中毒的临床症状包括在羊、牛和猪身上报告的症状——共济失调、不协调、肌肉无力、虚脱和死亡。另一方面，一种含有喹里西啶生物碱的植物羽扇豆（尾杯羽扇豆）也已知会导致奶牛MCC，但对怀孕山羊仅造成轻微的毒性症状，对其后代没有致畸作用。