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3-Methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH.
Bioorganic & Medicinal Chemistry Letters ( IF 2.5 ) Pub Date : 2003-12-20 , DOI: 10.1016/j.bmcl.2003.10.017 Hormuzd R Mulla 1 , Nicholas J Agard , Amit Basu
Bioorganic & Medicinal Chemistry Letters ( IF 2.5 ) Pub Date : 2003-12-20 , DOI: 10.1016/j.bmcl.2003.10.017 Hormuzd R Mulla 1 , Nicholas J Agard , Amit Basu
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Several boronic acids were screened for their ability to bind to diols. 3-methoxycarbonyl-5-nitrophenyl boronic acid bound to both a catechol dye as well as fructose with a comparable affinity to that of an ortho-methylamino substituted boronic acid. This work suggests a greater role for appropriately functionalized electron deficient boronic acids in diol and carbohydrate recognition.
中文翻译:
3-甲氧羰基-5-硝基苯基硼酸:在中性pH下具有高亲和力的二醇识别。
筛选了几种硼酸与二醇结合的能力。3-甲氧基羰基-5-硝基苯基硼酸结合邻苯二酚染料和果糖,其亲和力与邻甲基氨基取代的硼酸相当。这项工作表明适当功能化的电子缺陷性硼酸在二醇和碳水化合物识别中的作用更大。
更新日期:2019-11-01
中文翻译:
3-甲氧羰基-5-硝基苯基硼酸:在中性pH下具有高亲和力的二醇识别。
筛选了几种硼酸与二醇结合的能力。3-甲氧基羰基-5-硝基苯基硼酸结合邻苯二酚染料和果糖,其亲和力与邻甲基氨基取代的硼酸相当。这项工作表明适当功能化的电子缺陷性硼酸在二醇和碳水化合物识别中的作用更大。