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Hysteroscopic Resection of Endometrial Polyps and Assisted Reproductive Technology Pregnancy Outcomes Compared with No Treatment: A Systematic Review
Journal of Minimally Invasive Gynecology ( IF 3.5 ) Pub Date : 2019-05-01 , DOI: 10.1016/j.jmig.2018.10.024
Huixia Zhang 1 , Xueqing He 1 , Wenyan Tian 1 , Xueru Song 1 , Huiying Zhang 2
Affiliation  

Endometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy outcomes of patients who underwent ART. The primary outcomes were clinical pregnancy, live birth, miscarriage, and implantation rates after ART. Eight studies with a total of 2267 patients were included. The results showed that hysteroscopic resection of endometrial polyps (mean size <2 cm) was associated with an increased rate of clinical pregnancy in patients who underwent intrauterine insemination. No clear benefit was observed for clinical pregnancy, live birth, miscarriage, or implantation rates in patients who underwent in vitro fertilization/intracytoplasmic sperm injection cycles. In conclusion, the effect of hysteroscopic polypectomy on pregnancy outcomes of patients who have undergone ART remains unclear. More prospective, randomized controlled trials are warranted to determine appropriate treatment.

中文翻译:

宫腔镜子宫内膜息肉切除术和辅助生殖技术与不治疗相比的妊娠结局:系统评价

子宫内膜息肉经常出现在不孕妇女的子宫腔中。关于接受辅助生殖技术 (ART) 的患者的子宫内膜息肉的治疗存在很多争论。通过在 PubMed、Embase 和 Cochrane 图书馆中搜索回顾性或前瞻性研究,进行了一项系统评价,这些研究比较了宫腔镜息肉切除术与未治疗的宫腔镜息肉切除术对接受 ART 患者妊娠结局的影响。主要结局是ART后的临床妊娠、活产、流产和植入率。共纳入 8 项研究,共 2267 名患者。结果表明,宫腔镜下子宫内膜息肉切除术(平均大小<2 cm)与接受宫内人工授精的患者的临床妊娠率增加有关。在接受体外受精/卵胞浆内单精子注射周期的患者中,未观察到临床妊娠、活产、流产或着床率有明显益处。总之,宫腔镜息肉切除术对接受 ART 患者妊娠结局的影响尚不清楚。需要更多前瞻性、随机对照试验来确定适当的治疗方法。
更新日期:2019-05-01
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