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Perioperative Hypoxia Secondary to Phenazopyridine-induced Methemoglobinemia in an Adolescent Patient Without Renal Insufficiency or Overdose: An Unusual Case.
Urology ( IF 2.1 ) Pub Date : 2019-03-24 , DOI: 10.1016/j.urology.2019.03.017 Parth K Shah 1 , Kate H Kraft 1
Urology ( IF 2.1 ) Pub Date : 2019-03-24 , DOI: 10.1016/j.urology.2019.03.017 Parth K Shah 1 , Kate H Kraft 1
Affiliation
Phenazopyridine is a common, well-tolerated medication with minimal side effects. Severe side effects are rare and include methemoglobinemia in setting of overdose, elderly patients, renal insufficiency, and chronic use. Here, we report a case of methemoglobinemia-induced perioperative hypoxia in an adolescent patient without renal insufficiency or overdose which has not been reported previously. This case underscores the importance of judicious use of this medication in all patients but notably in pediatric patients and those with chronic lung disease.
中文翻译:
在没有肾功能不全或用药过量的青少年患者中,继发于苯并吡啶诱发的血红蛋白血症的围手术期缺氧:不常见的情况。
苯偶氮吡啶是一种常见的,耐受性良好的药物,副作用最小。严重的副作用很少见,包括服用过量的高铁血红蛋白血症,老年患者,肾功能不全和长期使用。在这里,我们报道了一例高铁血红蛋白血症引起的围手术期缺氧的病例,该患者在没有肾功能不全或用药过量的情况下未曾报道过。该病例强调了在所有患者中明智使用这种药物的重要性,尤其是在儿科患者和患有慢性肺病的患者中。
更新日期:2019-11-01
中文翻译:
在没有肾功能不全或用药过量的青少年患者中,继发于苯并吡啶诱发的血红蛋白血症的围手术期缺氧:不常见的情况。
苯偶氮吡啶是一种常见的,耐受性良好的药物,副作用最小。严重的副作用很少见,包括服用过量的高铁血红蛋白血症,老年患者,肾功能不全和长期使用。在这里,我们报道了一例高铁血红蛋白血症引起的围手术期缺氧的病例,该患者在没有肾功能不全或用药过量的情况下未曾报道过。该病例强调了在所有患者中明智使用这种药物的重要性,尤其是在儿科患者和患有慢性肺病的患者中。