The kanchanamycins, a group of novel 36-membered polyol macrolide antibiotics were detected in the culture filtrate and mycelium of Streptomyces olivaceus Tü 4018 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compounds show antibacterial and antifungal activities, and are especially effective against Pseudomonas fluorescens. Besides the kanchanamycin complex, strain Tü 4018 produces the 42-membered macrolactones, oasomycin A and desertomycin A, as well as tryptophan-dehydrobutyrine diketopiperazine and daidzein.

中文翻译：

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Kanchanamycins，由寡链霉菌Tü4018生产的新型多元醇大环内酯类抗生素。I.分类学，发酵，分离和生物学活性。

通过HPLC-二极管阵列和HPLC-电喷雾-质谱法筛选，在培养液和寡链霉菌Tü4018菌丝体中检测到了卡那霉素，这是一组新型的36元多元醇大环内酯类抗生素。该化合物具有抗菌和抗真菌活性，对荧光假单胞菌特别有效。除了看黄霉素复合物外，Tü4018菌株还产生42元的大内酯，绿霉素A和沙漠霉素A，以及色氨酸-脱氢酪氨酸二酮哌嗪和大豆苷元。