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Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination.
The Journal of Antibiotics ( IF 2.1 ) Pub Date : 1988-08-01 , DOI: 10.7164/antibiotics.41.1015
S Yoshida 1 , H Naganawa , T Aoyagi , T Takeuchi , H Umezawa
Affiliation  

Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase, has been isolated from the culture broth of Streptomyces flavovirens MH499-O'F1. The structure of benadrostin was defined as 8-hydroxy-2H-1,3-benzoxazine-2,4-dione by an analysis of spectral properties and chemical studies of benadrostin and its derivatives.

中文翻译:

Benadrostin,由放线菌产生的新型聚(ADP-核糖)合成酶抑制剂。二。结构确定。

Benadrostin,一种新型的聚(ADP-核糖)合成酶抑制剂,已从黄链霉菌MH499-O'F1的培养液中分离出来。通过对贝纳斯汀及其衍生物的光谱性质分析和化学研究,将贝纳斯汀的结构定义为8-羟基-2H-1,3-苯并恶嗪-2,4-二酮。
更新日期:2019-11-01
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