Glutathione conjugation (GS-atrazine) of the herbicide, 2-chloro-4-ethylamino-6-isopropylamino-s-triazine (atrazine) is another major detoxication mechanism in leaf tissue of corn (Zea mays, L.). The identification of GS-atrazine is the first example of glutathione conjugation as a biotransformation mechanism of a pesticide in plants. Recovery of atrazine-inhibited photosynthesis was accompanied by a rapid conversion of atrazine to GS-atrazine when the herbicide was introduced directly into leaf tissue. N-De-alkylation pathway is relatively inactive in both roots and shoots. The nonenzymatic detoxication of atrazine to hydroxyatrazine is negligible in leaf tissue. The hydroxylation pathway contributed significantly to the total detoxication of atrazine only when the herbicide was introduced into the plant through the roots. The metabolism of atrazine to GS-atrazine may be the primary factor in the resistance of corn to atrazine.

中文翻译：

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谷胱甘肽结合：玉米中阿特拉津解毒机制。

除草剂 2-chloro-4-ethylamino-6-isopropylamino-s-triazine (atrazine) 的谷胱甘肽结合 (GS-atrazine) 是玉米 (Zea mays, L.) 叶组织中的另一种主要解毒机制。GS-莠去津的鉴定是谷胱甘肽结合作为植物中农药生物转化机制的第一个例子。当将除草剂直接引入叶组织时，莠去津抑制的光合作用的恢复伴随着莠去津快速转化为 GS-莠去津。N-脱烷基化途径在根和芽中相对不活跃。阿特拉津对羟基阿特拉津的非酶解毒作用在叶组织中可以忽略不计。只有当除草剂通过根部引入植物时，羟基化途径才能显着促进阿特拉津的完全解毒。