当前位置: X-MOL 学术 › Pharmazie › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Biological activity and health promoting effects of psoralidin.
Die Pharmazie Pub Date : 2019-02-21 , DOI: 10.1691/ph.2019.8619
Rui Zhang , Weimei Shi , Linfu Li , Xianhua Huang , Daohua Xu , Longhuo Wu

Psoralidin, a prenylated coumestrol isolated from the seed of a traditional Chinese medicine Psoralea corylifolia L., has been demonstrated to exhibit anti-inflammatory, anti-cancer, anti-oxidative, estrogenic, neuroprotective, anti-bacterial, and anti-parasite activities. Due to prenylation, psoralidin exhibits stronger estrogenic activity with no obvious adverse effects and shows a close association with management of osteoporosis and some cancers. However, the hydrophobicity and low bioavailability of psoralidin limit its clinical application, although recent investigation has gained valuable data. This review will discuss the biological activities of psoralidin in health.

中文翻译:

补骨脂素的生物活性和健康促进作用。

补骨脂素(Psoralidin)是一种从传统中草药补骨脂(Psoralea corylifolia L.)的种子中分离得到的烯丙基香豆素,具有抗炎,抗癌,抗氧化,雌激素,神经保护,抗菌和抗寄生虫活性。由于异戊二烯化,补骨脂素表现出较强的雌激素活性,没有明显的不良作用,并且与骨质疏松症和某些癌症的治疗密切相关。然而,补骨脂素的疏水性和低生物利用度限制了其临床应用,尽管最近的研究已经获得了有价值的数据。这篇综述将讨论补骨脂素在健康中的生物学活性。
更新日期:2019-11-01
down
wechat
bug