Platelet-rich plasma (PRP) is being used increasingly often in the clinical setting to treat tendon-related pathologies. Yet the optimal PRP preparations to promote tendon healing in different patient populations are poorly defined. Here, we sought to determine whether increasing the concentration of platelet-derived proteins within a derivative of PRP, platelet lysate (PL), enhances tenocyte proliferation and migration in vitro, and whether the mitogenic properties of PL change with donor age.

中文翻译：

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来自老年供体的血小板裂解物以浓度依赖性方式促进人肌腱细胞增殖和迁移。

富血小板血浆 (PRP) 在临床环境中越来越多地用于治疗肌腱相关病变。然而，在不同患者群体中促进肌腱愈合的最佳 PRP 制剂尚不明确。在这里，我们试图确定增加 PRP 衍生物血小板裂解物 (PL) 中血小板衍生蛋白的浓度是否会增强体外肌腱细胞增殖和迁移，以及 PL 的有丝分裂特性是否随供体年龄而变化。