小儿丁烷气中毒导致的心肌梗死的事后诊断：一例报告。,The American Journal of Forensic Medicine and Pathology

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小儿丁烷气中毒导致的心肌梗死的事后诊断：一例报告。
The American Journal of Forensic Medicine and Pathology ( IF 1.0 ) Pub Date : 2018-10-10 , DOI: 10.1097/paf.0000000000000435
Aytul Bugra ₁ , Taner Das

Affiliation

挥发性物质成瘾和有毒气体吸入现在是一个重要的健康问题。愉悦地吸入丁烷气（也称为较轻的补充气）在儿童和年轻人中尤为普遍。造成这种情况的最重要原因是它们便宜且容易获得，并且缺乏法律监督。呼出的气体通过肺泡表面吸收，并迅速进入血液并导致临床体征。在急性期可引起头晕，恶心，呕吐，意识模糊，幻觉和欣快感。在严重的情况下，会发生支气管痉挛，缺氧，室性心律不齐，心肺骤停和死亡。我们的病例是文献中通过尸检组织病理学检查诊断出的罕见病例之一。我们的案例是在烟草制品商店前被发现的一名15岁女孩。大体检查时，主动脉瓣下有出血区域，该区域一直持续到室间隔。没有冠状动脉病变。组织病理学检查显示心肌纤维中嗜酸性粒细胞增多和收缩带坏死，乳头肌中更严重。免疫组织化学研究也支持早期心肌缺血性改变。经毒理学检查，在肺和血液样本中检测到丁烷气。在乳头肌中更强烈。免疫组织化学研究也支持早期心肌缺血性改变。经毒理学检查，在肺和血液样本中检测到丁烷气。在乳头肌中更强烈。免疫组织化学研究也支持早期心肌缺血性改变。经毒理学检查，在肺和血液样本中检测到丁烷气。

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Postmortem Diagnosis of Myocardial Infarction Due to Butane Gas Intoxication in a Child: A Case Report.

Volatile substance addiction and toxic gas inhalation are now an important health problem. The pleasure-based inhalation of butane gas, also known as lighter refill gas, is especially prevalent among children and young people. The most important reasons for this situation are that they are cheap and easy to obtain and lack of legal supervision. The exhaled gas is absorbed through the alveolar surface and rapidly enters the bloodstream and leads to clinical signs. It can cause dizziness, nausea, vomiting, confusion, hallucinations, and euphoria in the acute phase. In severe cases, bronchospasm, hypoxia, ventricular arrhythmia, cardiopulmonary arrest, and death can occur. Our case is one of the rare cases in the literature that was diagnosed by postmortem histopathological examination. Our case is a 15-year-old girl who was found in front of a tobacco product store. On gross examination, there was a hemorrhagic area under the aortic valve that continued to interventricular septum. There was no coronary artery lesion. Histopathological examination revealed hypereosinophilia and contraction band necrosis in myocardial fibers, which was more intense in papillary muscle. Immunohistochemical studies also supported early myocardial ischemic changes. Upon toxicological examination, butane gas was detected in lung and blood samples.

更新日期：2020-12-17

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