BACKGROUND Onychopapilloma (OP) is a benign longitudinal nail bed tumour usually presenting as longitudinal erythronychia. Evidence-based recommendations for proper histologic sectioning and definitive surgical management are not available. OBJECTIVES The aim of this study was threefold. The first was to review the clinical and histopathological features of all OP diagnosed in our department. The second was to identify the most accurate histological technique. The third aim was to determine the most effective surgical procedures by examining recurrence rates and complications over the long term. METHODS This retrospective analysis collected all patients with OP in the dermatology department of Saint-Pierre - Brugmann University Hospital (Brussels, Belgium) between January 2007 and March 2017. Clinical findings and type of surgery performed were recorded from medical files and iconographic documents. All slides were reviewed by a dermatopathologist with expertise in nail disease. Longitudinal follow-up was performed. RESULTS A total of 68 patients were included (42 women, 26 men) with a median age of 46 years. Two children were 9 and 11. The histological interpretation was more difficult for the transverse sections than for the longitudinal ones (29.4% vs. 2.2%). The pathological diagnosis of OP was typical in 30.6%, suggestive in 51.6%, slightly suggestive in 12.9% and not contributive in 4.8%. 50 patients had a mean follow-up of 50 months. 38% recovered completely and 20% recurred. 42% had mild to moderate sequelae. CONCLUSIONS We report herein the first two paediatric cases. Classical longitudinal excision with careful removal of the lesion from the inferior face of the nail plate seems to be the most accurate surgical technique. In the pathology laboratory, longitudinal sections should be recommended. In our series, a recurrence rate of 20% was observed. This was more frequent when a tangential longitudinal excision was performed.

中文翻译：

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甲样乳头状瘤：68例病例，以确定最佳手术方法和组织学切片。

背景技术甲癣（OP）是一种良性的纵向指甲床肿瘤，通常表现为纵向红斑。没有适当的组织学切片和明确的手术管理的循证医学建议。目的本研究的目的是三方面的。首先是审查在我们部门诊断出的所有OP的临床和组织病理学特征。第二是确定最准确的组织学技术。第三个目标是通过长期检查复发率和并发症来确定最有效的手术程序。方法这项回顾性分析收集了2007年1月至2017年3月在圣皮埃尔-布鲁格曼大学医院（比利时布鲁塞尔）皮肤科的所有OP患者。从医学档案和图像文件中记录临床发现和手术类型。所有载玻片均由具有指甲疾病专业知识的皮肤病理学家复习。进行纵向随访。结果共纳入68位患者（42位女性，26位男性），中位年龄为46岁。两个孩子分别是9岁和11岁。横截面的组织学解释要比纵向的困难（29.4％比2.2％）。OP的病理诊断典型率为30.6％，提示为51.6％，稍提示为12.9％，无贡献为4.8％。50例患者平均随访50个月。38％的患者完全康复，而20％的患者复发。42％有轻度至中度后遗症。结论我们在此报告前两个小儿病例。经典的纵向切除术并仔细从指甲板下表面去除病变似乎是最准确的手术技术。在病理实验室，应推荐纵切面。在我们的系列中，观察到复发率为20％。当执行切向纵向切除时，这种情况更为常见。