The current investigation sought to evaluate the relation between hemorheological properties and the metabolic syndrome. 1400 office workers aged 35 to 59 years were enrolled in this study. Waist circumference and blood pressure were determined. Plasma high-density lipoprotein (HDL cholesterol), triglyceride, fasting blood glucose, plasma insulin and whole blood viscosity (WBV) at a high-shear rate of 200 s(-1) were measured at the attendance. Metabolic syndrome was defined according to National Cholesterol Education Program (NCEP)/ATP III guidelines. The metabolic syndrome was identified in 18% of this sedentary population. Mean WBV was 4.71+/-0.56 mPa s. One-way ANOVA indicated WBV increased across subjects with 0-4 metabolic syndrome components (F=3.86, p<0.01). The highest vs. lowest quartiles of WBV occurred significantly more often among subjects as the number of metabolic syndrome components increased. Across five categories of the metabolic syndrome, the frequencies of the occurrence of the highest vs. lowest quartiles were: 0.40, 0.87, 1.31, 1.92, and 4.80, respectively, showing a significant correlation (R=0.817, p<0.05). Univariate logistic regression analysis showed that the prevalence of hyperviscosity was predicted positively by waist circumference (OR=1.018, 95% CI: 1.002-1.035, p<0.05) and negatively by HDL cholesterol (OR=0.295, 95% CI: 0.133-0.680, p<0.01), independently of age, sex, and smoking status. In summary, this study has shown that WBV is strongly related to the severity of the metabolic syndrome. We suggest that the hemorheological parameters could potentially be used as an additional indicator of the metabolic syndrome.

中文翻译：

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血液流变学特性与中年人的代谢综合征密切相关。

当前的研究试图评估血液流变性质与代谢综合征之间的关系。这项研究招募了1400名35至59岁的上班族。确定腰围和血压。出席者以200 s（-1）的高剪切速率测量血浆高密度脂蛋白（HDL胆固醇），甘油三酸酯，空腹血糖，血浆胰岛素和全血粘度（WBV）。根据国家胆固醇教育计划（NCEP）/ ATP III指南定义了代谢综合征。在这个久坐的人群中有18％患有代谢综合征。平均WBV为4.71 +/- 0.56 mPa s。单向方差分析表明，WBV在具有0-4个代谢综合征成分的受试者中增加（F = 3.86，p <0.01）。最高vs. 随着新陈代谢综合症成分数量的增加，WBV最低四分位数的发生率在受试者中更为频繁。在代谢综合征的五类中，最高四分位数与最低四分位数的发生频率分别为：0.40、0.87、1.31、1.92和4.80，显示出显着的相关性（R = 0.817，p <0.05）。单因素Logistic回归分析显示，高腰围患病率由腰围呈正向预测（OR = 1.018，95％CI：1.002-1.035，p <0.05），由HDL胆固醇呈负向预测（OR = 0.295，95％CI：0.133-0.680） ，p <0.01），与年龄，性别和吸烟状况无关。总之，这项研究表明，WBV与代谢综合征的严重程度密切相关。