Bioglue：在胸外科中使用这种新型外科手术粘合剂的综述。,ANZ Journal of Surgery

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Bioglue：在胸外科中使用这种新型外科手术粘合剂的综述。
ANZ Journal of Surgery ( IF 1.5 ) Pub Date : 2005-06-04 , DOI: 10.1111/j.1445-2197.2005.03350.x
Jurgen Passage ₁ , Robert Tam , Morgan Windsor , Mark O'Brien

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背景技术胸外科手术后的肺泡漏气和支气管胸膜瘘严重影响了医院的发病率和死亡率。BioGlue为胸外科医生提供了一种替代目前用于减少这些并发症发生率的产品的替代产品。这项回顾性研究回顾了我们使用这种新型粘合剂的经验。方法通过手术记录确定40名使用BioGlue的患者。收集术前，术中和术后数据以建立用途，适应症和结果。结果主要的基础病理是恶性肿瘤。在32例患者中，在初次手术期间使用了BioGlue，而在其余8例中，持续的气密或淋巴渗漏导致进一步的手术需要使用胶水。使用BioGlue的适应症包括肺泡漏气（36），支气管胸膜瘘（2）和淋巴漏（2）。有一个死亡。在36名出现肺泡漏气的患者中，有35名BioGlue在应用部位控制了漏气。结论我们在特定患者组中的结果表明，BioGlue是减少肺泡漏气的可靠辅助剂。尽管要确定BioGlue与其他密封胶相比在胸外科中的作用还需要进一步的研究，但这些初步结果是有希望的。

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Bioglue: a review of the use of this new surgical adhesive in thoracic surgery.

BACKGROUND Alveolar air leaks and broncho-pleural fistulae after thoracic surgical procedures contribute significantly to hospital morbidity and mortality. BioGlue has offered the thoracic surgeon an alternative to the products presently used to reduce the incidence of these complications. This retrospective study reviews our experience with this new adhesive. METHODS Forty patients upon whom BioGlue was used were identified through operation records. Pre-, intra- and postoperative data were collected to establish use, indications and outcome. RESULTS The predominant underlying pathology was malignancy. In 32 patients BioGlue was used during the primary procedure while in the remaining eight, persistent air- or lymph-leak led to a further procedure requiring the use of glue. The indications for BioGlue use were alveolar air leak (36), broncho-pleural fistula (2) and lymph leak (2). There was one death. In 35 out of 36 patients with alveolar air leak, BioGlue controlled the leak at the site of application. CONCLUSIONS Our results in this particular patient group indicate that BioGlue is a reliable adjunct in the reduction of alveolar air leaks. Although further studies are necessary to establish the role of BioGlue in thoracic surgery in comparison to other sealants, these initial results are promising.

更新日期：2019-11-01

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