Anaphylactic reactions to colloid volume substitutes, such as dextran, are rare, however, with their increasing utilization in clinical practice an increasing awareness of their potential antigenicity is required. This article reports a severe allergic reaction induced by infusion of dextran 40 during the beginning of a general anesthesia in a 59 year old patient who was going to be submitted to an operation for treatment of chagasic megacolon. The patient died from this complication after 28 days. A review of literature of this complication and a discussion about its physiopathological mechanism and prevention is presented.

中文翻译：

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右旋糖酐40输注后的过敏反应：一例报道并文献复习。

对胶体体积替代物（例如右旋糖酐）的过敏反应很少见，但是，随着它们在临床实践中的利用率不断提高，人们对其潜在抗原性的认识也越来越高。本文报道了一名59岁患者的全身麻醉开始时，右旋糖酐40的注入引起的严重的过敏反应，该患者将接受手术治疗chagasic megacolon。患者在28天后死于这种并发症。对此并发症的文献进行了综述，并对其生理病理机制和预防进行了讨论。