2,3-Butanediol is a promising bulk chemical due to its extensive industry applications. The state-of-the-art nature of microbial 2,3-butanediol production is reviewed in this paper. Various strategies for efficient and economical microbial 2,3-butanediol production, including strain improvement, substrate alternation, and process development, are reviewed and compared with regard to their pros and cons. This review also summarizes value added derivatives of biologically produced 2,3-butanediol and different strategies for downstream processing. The future prospects of microbial 2,3-butanediol production are discussed in light of the current progress, challenges, and trends in this field. Guidelines for future studies are also proposed.

2,3-丁二醇由于其广泛的工业应用而成为有前途的散装化学品。本文综述了微生物2,3-丁二醇生产的最新技术。审查并比较了各种高效，经济地生产微生物2,3-丁二醇的策略，包括菌株改良，底物交替和工艺开发的优缺点。这篇综述还总结了生物生产的2，3-丁二醇的增值衍生物和下游加工的不同策略。根据该领域的当前进展，挑战和趋势，讨论了微生物2,3-丁二醇生产的未来前景。还提出了未来研究的指南。