Pallidol is a naturally occurring resveratrol dimer from red wine with antioxidant and antifungal activities. In this report, with the use of the EPR spin-trapping technique, the scavenging and quenching effects of pallidol on reactive oxygen species (ROS) were investigated. The results demonstrated that pallidol showed strong quenching effects on singlet oxygen at very low concentrations, but it was ineffective to scavenge hydroxyl radicals or superoxide anions. Further kinetic study revealed that the reaction of pallidol with singlet oxygen had an extremely high rate constant (k(a)=1.71x10(10)). Therefore, pallidol is a potent and selective singlet oxygen quencher in aqueous systems. It may be used in singlet oxygen-mediated diseases as a pharmacological agent, which may contribute to the health beneficial effects of red wine.

中文翻译：

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Pallidol是一种来自红酒的白藜芦醇二聚体，是一种选择性单线态氧猝灭剂。

Pallidol是来自红酒的天然白藜芦醇二聚体，具有抗氧化剂和抗真菌活性。在本报告中，使用EPR自旋捕集技术，研究了pallidol对活性氧（ROS）的清除和猝灭作用。结果表明，pallidol在极低的浓度下对单重态氧显示出强大的猝灭作用，但对清除羟基自由基或超氧阴离子无效。进一步的动力学研究表明，pallidol与单线态氧的反应具有极高的速率常数（k（a）= 1.71x10（10））。因此，pallidol在水性体系中是一种有效的选择性单线态氧猝灭剂。它可以在单线态氧介导的疾病中用作药理剂，可能有助于红酒对健康的有益作用。