1994-2007年皮肤病生活质量指数：验证数据和临床结果的全面综述。,British Journal of Dermatology

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1994-2007年皮肤病生活质量指数：验证数据和临床结果的全面综述。
British Journal of Dermatology ( IF 11.0 ) Pub Date : 2008-09-18 , DOI: 10.1111/j.1365-2133.2008.08832.x
M K A Basra ₁ , R Fenech , R M Gatt , M S Salek , A Y Finlay

Affiliation

背景技术皮肤病生活质量指数（DLQI）是最广泛使用的针对皮肤病学的生活质量仪器之一。在过去的五年中，人们对它的使用产生了极大的兴趣。目的收集和展示从DLQI发布到2007年底的所有技术信息和DLQI的临床使用信息，以作为单一参考来源。方法使用电子参考数据库和加的夫大学皮肤科的DLQI库进行详细的文献检索。从开发到2007年底的所有有关DLQI的出版物都得到了确认，并从DLQI的心理计量分析以及在临床试验，流行病学研究和健康服务研究中使用了有关DLQI的数据，提取并列出所有相关参考资料。结果总共审查了272篇包括DLQI的文章。这些文章中描述的研究分为五个主要类别：心理测量研究，描述性/流行病学研究，药物（局部和全身）试验，临床实践研究和治疗干预。DLQI已在32个国家/地区的33种不同皮肤状况中使用，并提供55种语言版本。在115项研究中描述了DLQI的心理方面，例如有效性，可靠性，对变化的响应能力，因素结构和最小重要差异。DLQI已用于评估14种不同类型治疗干预措施有效性的33项研究中，以及评估9种临床实践研究的37项研究中。60项研究单独或与其他工具并行使用了它作为18种系统性药物临床试验的结果指标，而22项研究在14种不同的局部药物试验中使用了它。DLQI也已用于27个跨国研究中。结论在过去的14年中，DLQI的国际使用逐渐增加。DLQI的简洁易用性使其在临床实践和研究中广受欢迎。但是，特别是关于其一维性，差异项功能和最小的临床重要差异，存在许多问题，需要进一步研究。本文应通过为DLQI的不同方面提供一个随时可用的参考资源来促进DLQI的潜在用户的工作。

"点击查看英文标题和摘要"

The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results.

BACKGROUND The Dermatology Life Quality Index (DLQI) is one of the most widely used dermatology-specific quality of life instruments. Over the last 5 years there has been great interest in its use. OBJECTIVES To collect and present all information regarding the technical properties and the clinical use of the DLQI from the date it was published to the end of 2007 for use as a single source of reference. METHODS A detailed literature search was conducted using electronic reference databases and the DLQI library in the Department of Dermatology, Cardiff University. All publications mentioning any aspect of the DLQI, from the time of its development to the end of 2007, were identified and the data concerning the DLQI in terms of its psychometric analysis, and use in clinical trials, epidemiological studies and health services research, were extracted and tabulated with all the relevant references. RESULTS In total, 272 full articles which have included the DLQI were reviewed. Studies described in these articles were divided into five main categories: psychometric studies, descriptive/epidemiological studies, drug (topical and systemic) trials, clinical practice research, and therapeutic interventions. The DLQI has been used in 33 different skin conditions in 32 countries and is available in 55 languages. Psychometric aspects of the DLQI such as validity, reliability, responsiveness to change, factor structure, and minimal important difference were described in 115 studies. The DLQI has been used in 33 studies assessing the effectiveness of 14 different types of therapeutic interventions and in 37 studies evaluating nine types of clinical practice research. Sixty studies have used it alone or in parallel with other instruments as an outcome measure in clinical trials of 18 systemic drugs while 22 studies have used it in 14 different topical drug trials. The DLQI has also been used in 27 multinational studies. CONCLUSIONS During the last 14 years there has been a gradual increase in the international use of the DLQI. The brevity and simplicity of use of the DLQI has resulted in its popularity both in clinical practice and in research. However, there are various issues in particular regarding its unidimensionality, differential item functioning, and minimal clinically important difference, which require further research. This article should facilitate the work of potential users of the DLQI by providing a readily available source of references for different aspects of the DLQI.

更新日期：2019-11-01

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