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Ergosterol Peroxide: A Mushroom-Derived Compound with Promising Biological Activities-A Review.
International Journal of Medicinal Mushrooms ( IF 1.4 ) Pub Date : 2017-04-25 , DOI: 10.1615/intjmedmushrooms.v19.i2.10 Simon Merdivan 1 , Ulrike Lindequist 2
International Journal of Medicinal Mushrooms ( IF 1.4 ) Pub Date : 2017-04-25 , DOI: 10.1615/intjmedmushrooms.v19.i2.10 Simon Merdivan 1 , Ulrike Lindequist 2
Affiliation
Ergosterol peroxide (EP; 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol) is a C28-sterol and a component of many medicinal mushrooms. Since its discovery nearly a century ago, many sources and biological effects of this compound have been described. Effects range from antimicrobial to cytotoxic to immunosuppressive and other activities. This review covers biological investigations of EP, its activities, and possible mechanisms of action. EP is a promising candidate for drug development and contributes to the health-promoting effects of medicinal mushrooms.
中文翻译:
麦角固醇过氧化物:具有良好生物活性的蘑菇衍生化合物-综述。
麦角固醇过氧化物(EP;5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol)是一种C28-固醇,是许多药用蘑菇的组成部分。自将近一个世纪的发现以来,已经描述了该化合物的许多来源和生物学作用。作用范围从抗微生物药到细胞毒性再到免疫抑制和其他活性。这篇综述涵盖了对EP,其活性以及可能的作用机制的生物学研究。EP是药物开发的有前途的候选者,并有助于药用蘑菇的健康促进作用。
更新日期:2019-11-01
中文翻译:
麦角固醇过氧化物:具有良好生物活性的蘑菇衍生化合物-综述。
麦角固醇过氧化物(EP;5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol)是一种C28-固醇,是许多药用蘑菇的组成部分。自将近一个世纪的发现以来,已经描述了该化合物的许多来源和生物学作用。作用范围从抗微生物药到细胞毒性再到免疫抑制和其他活性。这篇综述涵盖了对EP,其活性以及可能的作用机制的生物学研究。EP是药物开发的有前途的候选者,并有助于药用蘑菇的健康促进作用。