A new polychlorinated triphenyl diether named microsphaerol (1), has been isolated from the endophtic fungus Microsphaeropsis sp. An intensive phytochemical investigation of the endophytic fungus Seimatosporium sp., led to the isolation of a new naphthalene derivative named seimatorone (2) and eight known compounds, i.e., 1-(2,6-dihydroxyphenyl)-3-hydroxybutan-1-one (3), 1-(2,6-dihydroxyphenyl)butan-1-one (4), 1-(2-hydroxy-6-methoxyphenyl)butan-1-one (5), 5-hydroxy-2-methyl-4H-chromen-4-one (6), 2,3-dihydro-5-hydroxy-2-methyl-4H-chromen-4-one (7), 8-methoxynaphthalen-1-ol (8), nodulisporins A and B (9 and 10, resp.), and daldinol (11). The structures of 1 and 2 were elucidated by detailed spectroscopic analysis including (1) H- and (13) C-NMR, COSY, HMQC, HMBC, and HR-EI-MS, while the structures of the known compounds were deduced from comparison of their spectral data with those in the literature. Preliminary studies revealed that microsphaerol (1) showed good antibacterial activities against B. Megaterium and E. coli, and good antilagal and antifungal activities against C. fusca, M. violaceum, respectively. On the other hand, seimatorone (2) exhibited moderate antibacterial, antialgal, and antifungal activities.

中文翻译：

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Microsphaerol和seimatorone：从内生真菌，Microsphaeropsis sp。分离出的两种新化合物。和Seimatosporium sp.。

从内生真菌Microsphaeropsis sp。中分离出了一种新的多氯代三苯二醚，称为微细酚（1）。对内生真菌Seimatosporium sp。的深入植物化学研究导致分离出一种新的萘衍生物，名为seimatorone（2）和八种已知化合物，即1-（2,6-二羟基苯基）-3-羟基丁-1- （3），1-（2,6-二羟基苯基）丁-1-酮（4），1-（2-羟基-6-甲氧基苯基）丁-1-酮（5），5-羟基-2-甲基- 4H-chromen-4-one（6），2,3-二氢-5-羟基-2-甲基-4H-chromen-4-one（7），8-甲氧基萘-1-醇（8），结瘤菌素A和B（分别为9和10）和daldinol（11）。通过详细的光谱分析阐明了1和2的结构，这些光谱分析包括（1）H-和（13）C-NMR，COSY，HMQC，HMBC和HR-EI-MS，而已知化合物的结构是通过将其光谱数据与文献中的光谱数据进行比较得出的。初步研究表明，微粉酚（1）分别具有对B. Megaterium和E. coli的良好抗菌活性，以及​​对C. fusca和M. violaceum的良好抗腹泻和抗真菌活性。另一方面，seimatorone（2）表现出中等的抗菌，抗藻类和抗真菌活性。