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Relevance of carnosic acid to the treatment of several health disorders: Molecular targets and mechanisms.
Biomedicine & Pharmacotherapy ( IF 6.9 ) Pub Date : 2016-10-04 , DOI: 10.1016/j.biopha.2016.09.067
Sana Bahri 1 , Saloua Jameleddine 2 , Vadim Shlyonsky 3
Affiliation  

Carnosic acid is a phenolic diterperne compound found in abundance in sage and rosemary, which are both widely used in traditional medicine. Research over the past decade indicates that carnosic acid has multiple bioactive properties including antioxidant, anti-inflammatory and anticancer activities among others. This review summarizes the current in vitro and in vivo data about the efficacy of carnosic acid in the prevention or treatment of various experimental health disorders. The analysis of the literature allows an insight into the participation of numerous signaling pathways modulated by carnosic acid, into its synergistic potential and, thus, into the divergence in cellular mechanisms of action of this molecule.

中文翻译:

肌酸与多种健康疾病的治疗相关性:分子靶标和机制。

鼠尾草酸是在鼠尾草和迷迭香中发现的丰富的酚二萜化合物,它们在传统医学中都广泛使用。过去十年的研究表明,肌酸具有多种生物活性,包括抗氧化剂,抗炎和抗癌活性。这篇综述总结了有关肌酸在预防或治疗各种实验性健康疾病中的功效的最新体外和体内数据。文献分析使我们能够洞悉肌酸调节的许多信号传导途径,其协同潜能,从而了解该分子的细胞作用机制的差异。
更新日期:2019-11-01
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