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A review on the pharmacological effects of vitexin and isovitexin.
Fitoterapia ( IF 2.5 ) Pub Date : 2016-10-30 , DOI: 10.1016/j.fitote.2016.09.011
Miao He 1 , Jia-Wei Min 1 , Wei-Lin Kong 1 , Xiao-Hua He 1 , Jun-Xu Li 2 , Bi-Wen Peng 1
Affiliation  

Vitexin and isovitexin are active components of many traditional Chinese medicines, and were found in various medicinal plants. Vitexin (apigenin-8-C-glucoside) has recently received increased attention due to its wide range of pharmacological effects, including but not limited to anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects. Isovitexin (apigenin-6-C-glucoside), an isomer of vitexin, generally purified together with vitexin, also exhibits diverse biological activities. Latest research has suggested that vitexin and isovitexin could be potential substitute medicines for diversity diseases, and may be adjuvants for stubborn diseases or health products. This review summarized recent findings on various pharmacological activities and associative signalling pathways of vitexin and isovitexin to provide a reference for future research and clinical applications.

中文翻译:

vitexin和isovitexin的药理作用综述。

Vitexin和isovitexin是许多中药的活性成分,并在各种药用植物中发现。由于其广泛的药理作用,包括但不限于抗氧化剂,抗癌药,抗炎药,抗痛觉过敏药和神经保护药,Vitexin(芹菜素-8-C-葡萄糖苷)最近受到了越来越多的关注。通常与vitexin一起纯化的异黄酮毒素(芹菜素6-C-葡糖苷)是vitexin的异构体,也具有多种生物活性。最新研究表明,葡萄黄素和异维毒素可能是多样性疾病的潜在替代药物,并且可能是顽固性疾病或保健品的佐剂。
更新日期:2019-11-01
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