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Synthesis, spectral studies and biological evaluation of 2-aminonicotinic acid metal complexes.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy ( IF 4.3 ) Pub Date : 2016-03-06 , DOI: 10.1016/j.saa.2016.02.022
Muhammad Nawaz 1 , Muhammad Waseem Abbasi 2 , Soleiman Hisaindee 3 , Muhammad Javed Zaki 2 , Hira Fatima Abbas 4 , Hu Mengting 5 , M Arif Ahmed 6
Affiliation  

We synthesized 2-aminonicotinic acid (2-ANA) complexes with metals such as Co(II), Fe(III), Ni(II), Mn(II), Zn(II), Ag(I),Cr(III), Cd(II) and Cu(II) in aqueous media. The complexes were characterized and elucidated using FT-IR, UV-Vis, a fluorescence spectrophotometer and thermo gravimetric analysis (TGA). TGA data showed that the stoichiometry of complexes was 1:2 metal/ligand except for Ag(I) and Mn(II) where the ratio was 1:1. The metal complexes showed varied antibacterial, fungicidal and nematicidal activities. The silver and zinc complexes showed highest activity against Bacillus subtilis and Bacillus licheniformis respectively. Fusarium oxysporum was highly susceptible to nickel and copper complexes whereas Macrophomina phaseolina was completely inert to the complexes. The silver and cadmium complexes were effective against the root-knot nematode Meloidogyne javanica.

中文翻译:

2-氨基烟酸金属配合物的合成,光谱研究和生物学评估。

我们合成了与金属如Co(II),Fe(III),Ni(II),Mn(II),Zn(II),Ag(I),Cr(III)的2-氨基烟酸(2-ANA)配合物,水性介质中的Cd(II)和Cu(II)。使用FT-IR,UV-Vis,荧光分光光度计和热重分析(TGA)对复合物进行表征和阐明。TGA数据表明,配合物的化学计量比为1:2的金属/配体,但Ag(I)和Mn(II)的比例为1:1。金属配合物表现出各种抗菌,杀真菌和杀线虫活性。银和锌配合物分别显示出对枯草芽孢杆菌和地衣芽孢杆菌的最高活性。尖孢镰刀菌(Fusarium oxysporum)对镍和铜配合物高度敏感,而菜豆(Macrophomina phaseolina)对配合物完全惰性。
更新日期:2019-11-01
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