In the present work, mesoporous structured estrone (E1) imprinted Fe3O4@SiO2@mSiO2 (MM-MIPs) was prepared and applied as extraction sorbent for selective pre-concentration and specific recognition of E1, 17β-estradiol (E2) and estriol (E3) from water samples. MM-MIPs present higher binding capacity, faster mass transfer and higher extraction efficiency for three estrogens than the non-porous structured Fe3O4@SiO2. Application of MM-MIPs to dispersive solid phase extraction of three estrogens from spiked tap, river and lake water samples at 0.5, 1.0, 10 μg L(-1) resulted in good recoveries ranging from 85% to 95% with relative standard deviation values lower than 6.0% in all cases. Limits of detection were in the range of 0.086-0.43 μg L(-1). The extraction method based on MM-MIPs proved to be a highly-effective enrichment method with enrichment factor about 1700, which is much higher than the value nearly 620 obtained by non-mesoporous Fe3O4@SiO2, during the process of simultaneous separation and sensitive determination of estrogens in complicated water samples. Furthermore, the mesoporous silica could be expanded to imprint other compounds.

中文翻译：

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介孔结构的雌酮印迹Fe3O4 @ SiO2 @ mSiO2，可通过HPLC对水样品中的雌激素进行高灵敏和选择性的检测。

在本工作中，制备了介孔结构的雌酮（E1）印迹的Fe3O4 @ SiO2 @ mSiO2（MM-MIPs），并将其用作萃取剂用于选择性地预浓缩和特异性识别E1、17β-雌二醇（E2）和雌三醇（E3） ）从水样中提取。与无孔结构的Fe3O4 @ SiO2相比，MM-MIPs对三种雌激素具有更高的结合能力，更快的质量传递和更高的提取效率。MM-MIPs在0.5、1.0、10μgL（-1）的加标自来水，河水和湖泊水样品中分散固相萃取三种雌激素的结果回收率在85％至95％之间，相对标准偏差值为在所有情况下均低于6.0％。检测限在0.086-0.43μgL（-1）范围内。事实证明，基于MM-MIPs的萃取方法是一种高效的富集方法，其富集因子约为1700，远高于同时分离和灵敏测定过程中非中等Fe3O4 @ SiO2所获得的近620的值。复杂水样中的雌激素含量 此外，中孔二氧化硅可以膨胀以压印其他化合物。