A straight forward strategy to synthesize purine nucleosides with multiple functionalization on 2-, 6-, and 8-positions has been developed successfully, which provides a series of 8-alkoxy-6-alkylamino-2-alkylthiopurine nucleosides in moderate to good yields for further biological and medical activity screening.

中文翻译：

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具有直接的多官能化策略的8-烷氧基-6-烷基氨基-2-烷基硫嘌呤核苷的合成

已经成功开发了一种简单的合成嘌呤核苷的简单策略，该嘌呤核苷在2、6和8位具有多个功能，可提供一系列中等收率到良好收率的8-烷氧基-6-烷基氨基-2-烷基硫代嘌呤核苷。进一步的生物学和医学活动筛选。