Intentional irradiation: We describe the reversible photoactivation of the acid‐sensitive pentameric ligand‐gated ion channel GLIC, achieved by using visible light irradiation of a newly synthesized water‐soluble merocyanine photoacid. The results demonstrate that irradiation can induce rapid, local pH changes that can be used to investigate the kinetics of proton transfer reactions.

中文翻译：

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与视觉和疼痛相关的酸敏感离子通道的光活化

故意照射：我们描述了酸敏感的五聚体配体门控离子通道GLIC的可逆光活化，这是通过使用新合成的水溶性部花菁光酸的可见光照射实现的。结果表明，辐照可引起局部快速pH改变，可用于研究质子转移反应的动力学。