新加坡南洋理工大学Qiao Yuan课题组招聘启事

Postdoctoral Positions in Microbiome Research

The Qiao Lab in the Division of Chemistry and Biological Chemistry (CBC), School of Physical and Mathematical Sciences (SPMS), Nanyang Technological University (NTU) in Singapore is seeking one talented postdoctoral fellow with expertise in microbiome research to join us.

Our group is interested in understanding the microbiota-host interactions from a chemical perspective. The identifications of microbiota-derived small molecules in the host circulatory system offer new insights on the broad-reaching effects of the gut microbiota. Recently, our studies showed that soluble bacterial peptidoglycan (PGN) fragments are ubiquitously present in sera of human and a number of animals including bovine, horse, sheep, rabbit and mice, but they are undetectable in germ-free mice. To explore the physiological relevance of microbiota-derived PGNs, we showed that modulating the PGN levels can affect autoimmune arthritis development in mice model, and interestingly, circulating PGNs are present at significantly higher levels in autoimmune disease patients such as RA and SLE. Thus, these circulating PGNs may act as signaling molecules in the microbe-host crosstalk.

Our research group takes multidisciplinary approach to understand the life cycle of these circulating PGNs from their origins, transportation, structures, distribution, and functions. Such insights do not only answer fundamental biology questions, but may also establish PGN as new effector molecules in the microbiota-host crosstalk, and lead to new therapeutic interventions. Our research is generously funded by the NTU Nanyang Assistant Professorship (NAP) start-up grant as well as the prestigious National Research Foundation Fellowship, Class of 2020.

For more information on our group, please visit our websites: https://www.yqiaolab.com  

The successful candidate should possess the following:

• A Ph.D. in microbiology, life science, system biology or related field.

• Expertise in microbiome sample handling, processing, and analyses. Expertise in bioinformatics is a plus.

• Highly motivated, committed, and capable to work independently as well as in a group.

• Strong publication record in peer-reviewed journals

• Good communication skills in English (both written and oral)

Postdoctoral Position in Natural Product Discovery

The Qiao Lab in the Division of Chemistry and Biological Chemistry (CBC), School of Physical and Mathematical Sciences (SPMS), Nanyang Technological University (NTU) in Singapore is seeking one postdoctoral fellow with expertise in natural product discovery to join us.

The successful candidate should possess the following:

• A Ph.D. in cell biology, biochemistry, chemistry or related fields.

• Expertise in natural product isolation and identification, in vitro assay development, protein engineering. Prior experiences with FPLC, HPLC, HR-LCMS/MS, NMR are required.

• Highly motivated, committed, and capable to work independently as well as in a group.

• Strong publication record in peer-reviewed journals

• Good communication skills in English (both written and oral)

Compensation and benefits package will be internationally competitive (including annual base salary, performance-based bonus, medical insurance and vacation leave), and will be commensurate with experiences and qualifications.

Interested candidates are encouraged to email a copy of CV (with a list of publications), a cover letter stating research accomplishment and interests, as well as contact information of three references to Dr. Qiao Yuan at yuan.qiao@ntu.edu.sg. Only selected candidates will be notified.