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吴夏泠 讲师 硕士生导师    

http://bec.jmu.edu.cn/info/1089/5776.htm

ORCID:0000-0001-6745-2982

Scopus Author ID: 57193709143

ResearcherID: X-3651-2018


联系方式:xlwu@jmu.edu.cn


教育经历

2014.9-2020.1 理学博士 北京大学 高分子化学与物理系 导师:张文彬 教授

2010.9-2014.7 理学学士 厦门大学 化学系


工作经历

2021.4 至今 集美大学 海洋食品与生物工程学院 讲师

2020.10-2021.4 集美大学 食品与生物工程学院 讲师


研究方向

1. 蛋白质化学反应对

2. 蛋白质工程

3. 生物活性材料


代表性科研项目

1. 国家自然基金,青年项目,2024-01-01至2026-12-31,30万,在研,主持

2. 福建省自然基金,面上项目,2023-08-01至2026-08-01,10万,在研,主持

3. 厦门市自然基金,青年项目,2023-07-01至2026-06-30,5万,在研,主持

4. 福建省教育厅,面上项目,2022-01-01至2024-12-31,1万,在研,主持



代表性科研论文

9. 王宇翔; 吴夏泠; 张文彬*, 生物活体功能材料研究进展.合成生物学, 2022, 3(4): 621-625.

8. Cheng, J.; Lin, X.; Wu, X.; Liu, Q.; Wan, S.; Zhang, Y.*, Preparation of a multifunctional silver nanoparticles polylactic acid food packaging film using mango peel extract, International Journal of Biological Macromolecules, 2021,188: 678-688. 

7. Da, X.-D.; Wu, X.-L.; Liu, Y.; Zhang, W.-B.* Protein Conjugation via SpyStapler-Mediated SpyTag/BDTag Coupling. Current Protocols 2021, 1(4): e99.

6. Zhang, X.-J.#; Wu, X.-L.#; Liu, D.; Da, X.-D.; Wang, X.-W.; Yang, S.*; Zhang, W.-B.*Engineering SpyCatcher Variants with Proteolytic Sites for Less-Trace Ligation. Chinese Journal of Chemistry 2019, 37: 113-118. (#equal contribution)

5. Wu, X.-L.#; Liu, Y. #; Liu, D.; Sun, F.; Zhang, W.-B.* An Intrinsically Disordered Peptide-Peptide Stapler for Highly Efficient Protein Ligation Both in Vivo and in Vitro. Journal of the American Chemistry Society 2018, 140: 17474-17483. (#equal contribution)

4. Zhang, X.-J. #; Wu, X.-L. #; Wang, X.-W.; Liu, D.; Yang, S.*; Zhang, W.-B.*, SpyCatcher-NTEV: A Circularly Permuted, Disordered SpyCatcher Variant for Less Trace Ligation. Bioconjugate Chemistry 2018, 29: 1622-1629.(#equal contribution)

3. Liu, D.#; Wu, W.-H.#; Liu, Y.-J.; Wu, X.-L.; Cao, Y.; Song, B.; Li, X.-P.; Zhang, W.-B.* Topology Engineering of Proteins in Vivo Using Genetically Encoded, Mechanically Interlocking SpyX Modules for Enhanced Stability. ACS Central Science 2017, 3: 473-481.

2. Liu, Y.-J.#;Liu, D.#; Yang, W.#; Wu, X.-L.; Lai, L.*;Zhang, W.-B.* Tuning SpyTag-SpyCatcher Mutant Pairs toward Orthogonal Reactivity Encryption. Chemical Science 2017, 8: 6577-6582. (#equal contribution)

1. Zhang, W.-B.*; Wu, X.-L.; Yin, G.-Z.; Shao, Y.; Cheng, S. D.* From Protein Domains to Molecular Nano Particles: What Can Giant Molecules Learn from Proteins? Materials Horizons 2017, 4: 117-132.



专利

1. 张文彬,吴夏泠,刘雅杰,刘栋,一种基于无序蛋白偶联酶的高效多肽-多肽偶联系统和方法,ZL 2019 1 0995483.6