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成果及论文

Hui Wang, Liping Guan, Xiaojuan Ma, Yiying Wang, Jinhao Wang, Peipei Zhang*, and Min Deng* Whole-Genome Sequencing Identified a Novel Mutation in the N-Terminal Domain of KIF5A in Chinese Patients with Familial Amyotrophic Lateral Sclerosis. Genes, 2024. 15,  DOI: 10.3390/genes15060680.(共同通讯)


W. Bi, Z. Xu, F. Liu, Z. Xie, H. Liu, X. Zhu, W. Zhong, P. Zhang*, and X. Tang*, Genome-wide analyses reveal the contribution of somatic variants to the immune landscape of multiple cancer types. PLoS Genet, 2024. 20(1): p. e1011134.(共同通讯)


Q. Zhang, W. Xian, Z. Li, Q. Lu, X. Chen, J. Ge, Z. Tang, B. Liu, Z. Chen, X. Gao, M. O. Hottiger, P. Zhang*, J. Qiu*, F. Shao, and X. Liu*, Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex. Cell Rep, 2024. 43(2): p. 113789.(共同通讯)


Peipei Zhang, Baochang Fan, Peiguo Yang, Jamshid Temirov, James Messing, Hong Joo Kim and J. Paul Taylor. (2019) Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. eLIFE. 2019;8:e39578


Kyung-Ha Lee*, Peipei Zhang*, Hong Joo Kim*, Diana M. Mitrea, Mohona Sarkar, Brian D. Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex, Brian A. Maxwell, Nam Chul Kim, Jamshid Temirov, Jennifer Moore, Regina-Maria Kolaitis, Timothy I. Shaw, Bing Bai, Junmin Peng, Richard W. Kriwacki, and J. Paul Taylor (2016) C9orf72 dipeptide repeats impair the assembly, dynamics and function of membrane-less organelles. Cell 167(3) : 774–788 (*共同一作)


Peipei Zhang and Hong Zhang. (2013) Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in C. elegans. EMBO reports 14(6), 568-576


W. Bi, W. Zhou, P. Zhang, Y. Sun, W. Yue, and S. Lee, Scalable mixed model methods for set-based association studies on large-scale categorical data analysis and its application to exome-sequencing data in UK Biobank. Am J Hum Genet, 2023. 110(5): p. 762-773.


Z. Yang, B. A. Johnson, V. A. Meliopoulos, X. Ju, P. Zhang, M. P. Hughes, J. Wu, K. P. Koreski, J. E. Clary, T. C. Chang, G. Wu, J. Hixon, J. Duffner, K. Wong, R. Lemieux, K. G. Lokugamage, R. E. Alvarado, P. A. Crocquet-Valdes, D. H. Walker, K. S. Plante, J. A. Plante, S. C. Weaver, H. J. Kim, R. Meyers, S. Schultz-Cherry, Q. Ding, V. D. Menachery, and J. P. Taylor, Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity. Cell Rep, 2024. 43(3): p. 113965.


Y. Jiang, S. Sun, X. Liu, K. Su, C. Zhang, P. Zhang, Z. Zhao, Y. Su, C. Wang, and X. Du, U3 snoRNA inter-regulates with DDX21 in the perichromosomal region to control mitosis. Cell Death Dis, 2024. 15(5): p. 342.


Youngdae Gwon, Brian A. Maxwell, Regina-Maria Kolaitis, Peipei Zhang, Hong Joo Kim, J. Paul Taylor; Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner. Science, 2021, 372(6549)

 

Peiguo Yang*, Cecile Mathieu*, Regina M. Kolaitis, Peipei Zhang, James Messing, Ugur Yurtsever, Zemin Yang, Jinjun Wu, Yuxin Li, Qingfei Pan, Jiyang Yu, Erik W. Martin, Tanja Mittag, Hong Joo Kim, J. Paul Taylor. (2020) G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules. Cell 181(2), 325–345

 


 

Michael R. White, Diana M. Mitrea, Peipei Zhang, Christopher B. Stanley, Devon E. Cassidy, Amanda Nourse, Aaron H. Phillips, Michele Tolbert, J. Paul Taylor, and Richard W. Kriwacki. (2019) C9orf72 poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function. Molecular Cell. 74, 713–728

 


 

Songqing Li, Peipei Zhang, Brian D. Freibaum, Nam Chul Kim, Regina-Maria Kolaitis, Amandine Molliex, Anderson P. Kanagaraj, Ichiro Yabe, Mishie Tanino, Shinya Tanaka, Hidenao Sasaki, Eric D. Ross, J. Paul Taylor and Hong Joo Kim. (2016) Genetic interaction of hnRNPA2B1 and DNAJB6 in a Drosophila model of multisystem proteinopathy. Hum Mol Genet 25(5): 936-50

 

Bin Guo*, Qianqian Liang*, Lin Li, Zhe Hu, Fan Wu, Peipei Zhang, Yongfen Ma, Bin Zhao, Attila L. Kovács, Zhiyuan Zhang, Du Feng, She Chen, Hong Zhang. (2014) O-GlcNAc modification regulates autophagosome maturation. Nat Cell Biol 16(12): 1215-26

 

Bin Guo*, Xinxin Huang*, Peipei Zhang, Linxiang Qi, Qianqian Liang, Xuebo Zhang, Jie Huang, Bin Fang, Wenru Hou, Jinghua Han, Hong Zhang. (2014) Genome-wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans development. EMBO reports 15(6): 705-713