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成果及论文

发表文章:

  1.  Liu D, Song D, Ning W, Zhang X, Chen S, Zhang H. Efficacy and safety of prophylaxis for venous thromboembolism in brain neoplasm patients undergoing neurosurgery: a systematic review and Bayesian network meta-analysis. J Thromb Thrombolysis. 2023 Feb 10. doi: 10.1007/s11239-023-02780-3. PMID: 36763224.
  2. Chen Y, Zhao C,Li S, Wang J, Zhang H*.Immune Microenvironment and Immunotherapies for Diffuse Intrinsic Pontine Glioma.Cancers 2023, 15(3), 602; https://doi.org/10.3390/cancers15030602.
  3. Chen Y, Guo Y, Li S, Xu J, Ning W, Zhao C, Wang J, Qu Y, Zhang M, Zhou W, Cui Q, Zhang H. Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress. Biomed Pharmacother. 2023 Jan;157:114037doi: 10.1016/j.biopha.2022.114037. Epub 2022 Nov 22. PMID: 36427388.
  4. Chen Y, Guo Y, Li S, Xu J, Wang X, Ning W, Ma L, Qu Y, Zhang M, Zhang H*. Identification of N6-Methyladenosine-Related lncRNAs as a Prognostic Signature in Glioma. Front Oncol. 2022 Mar 3;12:789283. doi: 10.3389/fonc.2022.789283. PMID: 35311131; PMCID: PMC8927984.
  5. Xu J, Guo Y, Ning W, Wang X, Li S, Chen Y, Ma L, Qu Y, Song Y*, Zhang H*. Comprehensive Analyses of Glucose Metabolism in Glioma Reveal the Glioma-Promoting Effect of GALM. Front Cell Dev Biol. 2022 Jan 20;9:717182. doi: 10.3389/fcell.2021.717182. PMID: 35127693; PMCID: PMC8811465.

  6. Guo Y, Li S, Huang P, Zhang H*, Yu C*. Development of a prognostic model based on an immunogenomic landscape analysis of medulloblastoma. Biosci Rep. 2021 Jan 29;41(1):BSR20202907. doi: 10.1042/BSR20202907. PMID: 33345275; PMCID: PMC7791544.

  7. X. Wang, W. Ning, Z. Qiu, S. Li, Hongwei Zhang*, C. Yu*, Tumor-associated macrophages based signaling pathway analysis and hub genes identification in glioma, Medicine (Baltimore). 99 (2020) e23840. 

  8. X. Wang#, Z. Qiu#, X. Ji, W. Ning, Y. An, S. Wang, Hongwei Zhang*, A novel workflow for cancer blood biomarker identification, Ann. Transl. Med. 8 (2020) 1430–1430

  9. Y. Guo, X. Wang, W. Ning, Hongwei Zhang*, C. Yu*, Identification of two core genes in glioblastomas with different isocitrate dehydrogenase mutation status, Mol. Biol. Rep. 47 (2020) 7477–7488. 

  10. P. Huang#, Y. Guo#, Z. Zhao, W. Ning, H. Wang, C. Gu, M. Zhang, Y. Qu, Hongwei Zhang*, Y. Song*, UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT, Aging (Albany. NY). 12 (2020) 10275–10289. /5/555

  11. Y. Guo#, P. Huang#, W. Ning, Hongwei Zhang*, C. Yu*, Identification of Core Genes and Pathways in Medulloblastoma by Integrated Bioinformatics Analysis, J. Mol. Neurosci. 70 (2020) 1702–1712.

  12. Ning, W. ,  Qiu, Z. ,  Ji, X. ,  Wang, X. , &  Zhang, Hongwei. (2020). The prognostic value of emt in glioma and its role in the glioma immune microenvironment. Journal of Molecular Neuroscience, 70(10).

  13. P. Wang#, W. Ning#, Y. Qu, Hongwei Zhang*, Cavernous Hemangioma of the Trochlear Nerve in Asian Population: Case Report and Review of the Literature, Neurol. India. (2020). 

  14. Y. Guo, R. Liu, L. Zhou, H. Zhao, F. Lv, L. Liu, Y. Huang*, Hongwei Zhang*, C. Yu*, S. Wang*, Blood-brain-barrier penetrable thiolated paclitaxel-oligo (p-phenylene vinylene) nanomedicine with increased drug efficiency for glioblastoma treatment, Nano Today. 35 (2020) 100969. 

  15. L. Ma, Y. Huang*, Hongwei Zhang*, W. Ning, R. Qi, H. Yuan, F. Lv, L. Liu, C. Yu*, S. Wang*, Sensitive Detection and Conjoint Analysis of Promoter Methylation by Conjugated Polymers for Differential Diagnosis and Prognosis of Glioma, ACS Appl. Mater. Interfaces. (2020) 

  16. Y. Guo, X. He, M. Zhang, Y. Qu, C. Gu, M. Ren, H. Wang, W. Ning, J. Li, C. Yu, Hongwei Zhang, Reciprocal control of ADAM17/EGFR/Akt signaling and miR-145 drives GBM invasiveness, J. Neurooncol. 147 (2020) 327–337.

  17. P Huang#; Y Guo#; HongWei Zhang*,Identification of Hub Genes in Pediatric Medulloblastoma by Multiple-Microarray Analysis, J Mol Neurosci,2019, 70(4): 522-531.

  18. Lei Xia, Mingshan Zhang, Yanming Qu, Ming Ren, Haoran Wang, Hongwei Zhang*, Chunjiang Yu*, Mingwang Zhu, Jianhua Li. Localization of transverse-sigmoid sinus junction using preoperative 3D computed tomography: application in retrosigmoid craniotomy. Neurosurgical Review, 2012,35(4),593-598

  19. Xuan Wang*, Hongwei Zhang*, Anling Zhang, Lei Han, Kun Wang, Ran Liu, Shaohua Yang, Peiyu Pu, Changhong Shen, Chunsheng Kang and Chunjiang Yu.  Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas. Oncology Reports, 2012,28(4),1293-1300 

  20. Lei Xia, Hongwei Zhang*, Chunjiang Yu, Mingshan Zhang, Ming Ren, Yanming Qu, Haoran Wang, Mingwang Zhu, Dianjiang Zhao, Xueling Qi, Kun Yao. Fluid-fluid level in cystic vestibular schwannomas: a predictor of peritumoral adhesion. Journal of Neurosurgery, 2014,120(1 ):197-206

  21. Hong-Wei Zhang*, Wei Sun, Jun Yang, et al. Diagnosis and treatment of pituitary microadenoma: report of 80 cases. Neurological Research, 2008,30: 587-593.

  22. Hailong Liu#,Weihai Ning#,Hongwei Zhang*. Primary intracranial malignant ectomesenchymoma in pineal region: a rare case report and review of literature, Int J Clin Exp Pathol, 2016,9(12):12993-13002

  23. 张东旭,曲彦明,张明山,任铭,谷春雨,王浩然,宁威海,郭玉铎,齐雪岭,张宏伟.(2019).WHO-Ⅱ级脑胶质瘤患者无进展生存期的影响因素分析.中华神经外科杂志,35(5),469-473.

  24. 宁威海, 张宏伟.侵略性垂体腺瘤的研究进展[J].临床神经外科杂志,2016(6).

  25. 张宏伟. 厚积薄发与因材施教———关于神经外科研究生培养的若干思考,卫生职业教育,2016年03期;

  26. 张宏伟. 浅谈并轨后临床专业硕士研究生培养的几点体会,西北医学教育,2016年2月第24卷第1期;

  27. 任铭, 张宏伟,张明山等.垂体瘤凝固性坏死七例报告并文献复习. 中华神经外科杂志,2014年, 30(2) :144-146

  28. 张宏伟,张明山,夏雷,曲彦明,李建华,任铭,王浩然,于春江. 经胼胝体-穹窿间入路切除第三脑室内部及其后部肿瘤的临床治疗探讨.中华外科杂志,2012,50(2),139-143

  29. 张宏伟, 鲍圣德. 改良大鼠颈动脉内膜剥脱模型的建立及其VCAM-1表达. 中国微侵袭神经外科杂志,2008,13(9):412-417

  30. 张宏伟,于春江,孙炜等. 首选溴隐亭治疗侵袭性巨大泌乳素腺瘤的综合治疗. 中华外科杂志,2006,44(22):1555-1557

  31. 张宏伟,鲍圣德,孙丕通等. 中药川芎嗪对蛛网膜下腔出血后脑血管痉挛的实验研究. 中国微侵袭神经外科杂志,2008,13(3):124-127

  32. 张宏伟,于春江,孙炜等. 误诊为鞍内肿瘤的动脉瘤2例报告并文献复习. 中国神经肿瘤杂志,2006, 4(2):96-99

  33. 张宏伟,于春江,闫长祥等. 垂体微腺瘤的诊断和治疗(附56例报告).中华神经外科杂志,2006, 22(6): 340-343.

  34. 张宏伟,于春江. 垂体微腺瘤的影像学特点和诊断(附36例报告). 中国微侵袭神经外科杂志,2005, 10(12):562-563.

  35. 张宏伟,张亚卓,于春江等. 成年大鼠骨髓基质细胞与划痕损伤星形胶质细胞相互作用后的形态学观察. 中国微侵袭神经外科杂志,2004,9(12):556-559

  36. 张宏伟,张亚卓,张海燕等. 星形胶质细胞诱导成年大鼠骨髓基质细胞分化成神经元样细胞的实验研究.中华神经外科杂志, 2004, 20(5):395-399.

  37. 张宏伟,张亚卓,张海霞等. 星形胶质细胞诱导成年大鼠骨髓基质细胞分化前后的电生理功能鉴定. 中华神经医学杂志,2004, 3(5): 324-326.


出版专著(含参编)

 《鞍区病变影像诊断与治疗策略》 人民卫生出版社  编著:于春江,张宏伟

 《神经内镜手术技术》 北京大学医学出版社  主编:张亚卓

 《颅底外科训练教程》 清华大学出版社  主编:于春江


承担课题

  1. 新型溶瘤病毒恶性肿瘤治疗及增效策略的研发(国家重点研发计划,重点专项),子课题,在研;
  2. 多病共患老年人生活质量维护及危险因素控制优化策略研究(国家重点研发计划),在研;
  3.  miR-224 靶向介导ADAM17调控儿童脑干胶质瘤细胞侵袭能力的机制研究(北京市教委科技计划重点项目),已结题;
  4. 显微手术切除听神经瘤面听神经功能保留的临床研究(首都临床特色应用研究),已结题;
  5. 脑血管病和中枢神经系统肿瘤综合防治技术的研发、转化与应用(卫生行业科研专项),子课题,已结题;
  6. 致敏树突状细胞联合过继T细胞对鼠脑恶性胶质瘤的治疗作用及其机制研究(国家自然科学基金),第二参与人,已结题;