教育经历

2012.09-2016.06 海南大学     海洋学院  工学学士

2016.09-2019.06 中国药科大学 中药学院  理学硕士

2024.09-至今    中南大学     湘雅医院  博士在读

工作经历

2019.07-2021.08 南欣研究院 药理负责人

2021.09-2024.08中盛溯源生物科技有限公司 药理负责人

研究方向

药理学

发明专利

（1）阮洁，徐明伦. 二萜化合物及其制备方法和在制备抗肿瘤药物中的应用CN112225656A. 2021.02.19

论文发表

（1）Ruan J, Liu L, Shan X, Xia B, Fu Q. Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling. Biosci Rep. 2019 Apr 26;39(4):BSR20190141.
（2）Song MT, Ruan J, Zhang RY, Deng J, Ma ZQ, Ma SP. Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis. Acta Pharmacol Sin. 2018 Oct;39(10):1559-1570.
（3）Tao W*, Ruan J*, Wu R, Zhao M, Zhao T, Qi M, Yau SSY, Yao G, Zhang H, Hu Y, Chen G. A natural carotenoid crocin exerts antidepressant action by promoting adult hippocampal neurogenesis through Wnt/β-catenin signaling. J Adv Res. 2023 Jan;43:219-231.
（4）Tao W*, Wang N*, Ruan J*, et al. Enhanced ROS-boosted phototherapy against pancreatic cancer via Nrf2-mediated stress-defense pathway suppression and ferroptosis induction[J]. ACS Applied Materials & Interfaces, 2022, 14(5): 6404-6416.
（5）Tao W, Cheng X, Sun D, Guo Y, Wang N, Ruan J, Hu Y, Zhao M, Zhao T, Feng H, Fan L, Lu C, Ma Y, Duan J, Zhao M. Synthesis of multi-branched Au nanocomposites with distinct plasmon resonance in NIR-II window and controlled CRISPR-Cas9 delivery for synergistic gene-photothermal therapy. Biomaterials. 2022 Aug;287:121621.

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