• 教育经历

2010.9-2014.6 桂林医学院 生物技术学院 理学学士

2014.9-2017.6 中山大学 肿瘤防治中心 理学硕士

2017.9-2021.6 中南大学 基础医学院 医学博士

• 工作经历

2021.7-2023.10 中南大学 基础医学院 博士后

2024.3-至今 中南大学湘雅医院 精准分子医学研究所 助理研究员

• 研究方向

肿瘤代谢与微环境

• 获得奖励

中南大学“升华博士后”称号  (2023)

癌变与侵袭原理研究国际会议暨青年论坛一等奖(2022)

中国干细胞第九届年会壁板三等奖（2019）

全国大学生英语竞赛二等奖(2013)

国家奖学金 (2012)

• 科研项目

国家自然科学基金青年科学基金项目（82200231） 主持（2023-2025）

中国博士后科学基金面上项目（2021M703631）主持（2022-2023）

国家自然科学基金重点项目（82130006）参与（2022-2026）

国家自然科学基金面上项目（81974010）参与（2020-2023）

国家自然科学基金青年科学基金项目（81800209） 参与（2019-2021）

国家自然科学基金面上项目（81771701）参与（2018-2021）

• 发明专利

（1）周文，匡春梅，周家喜，夏美娟，胡聪。血小板减少型多发性骨髓瘤的诊断制剂、治疗制剂。2022，中国，专利申请号：202211070658.0

• 论文发表

（1） Chunmei Kuang^#, Meijuan Xia^#, Gang An, CuiCui Liu, Cong Hu, Jingyu Zhang, Zhenhao Liu, Bin Meng, Pei Su, Jiliang Xia, Jiaojiao Guo, Yinghong Zhu, Xing Liu, Xuan Wu, Yi Shen, Xiangling Feng, Yanjuan He, Jian Li, Lugui Qiu, Jiaxi Zhou*, Wen Zhou*. Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma. Nat Commun. 2023;14(1):2093.

（2） Chunmei Kuang, Yinghong Zhu, Yongjun Guan, Jiliang Xia, Yangjian Ou, Guizhu Liu, Mu Hao, Jiabin Liu, Jiaojiao Guo, Wenxia Zhang, Xiangling Feng, Xin Li, Jingyu Zhang, Xuan Wu, Hang Xu, Guancheng Li, Lu Xie, Songqing Fan, Lugui Qiu, Wen Zhou*. COX2 confers bone marrow stromal cells to promoting TNFa/TNFR1b-mediated myeloma cell growth and adhesion. Cell Oncol. 2021;44(3):643-659.

（3） Chun-Mei Kuang^#, Xiang Fu^#, Yi-Jun Hua, Wen-di Shuai, Zhi-Hua Ye, Yingchang Li, Qi-Hua Peng, Yi-Zhuo Li, Shuai Chen, Chao-Nan Qian, Wenlin Huang*, Ran-Yi Liu*. BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer. Cell Death Dis. 2017;8(6):e2874. 

（4） Yihui Wang, Qin Yang, Yinghong Zhu, Xingxing Jian, Jiaojiao Guo, Jingyu Zhang, Chunmei Kuang, Xiangling Feng, Gang An, Lugui Qiu, Guancheng Li, Yanjuan He, Wen Zhou*. Intestinal Klebsiella pneumoniae Contributes to Pneumonia by Synthesizing Glutamine in Multiple Myeloma. Cancers (Basel). 2022;14(17):4188.

（5） Jiliang Xia, Yanjuan He, Bin Meng, Shilian Chen, Jingyu Zhang, Xuan Wu, Yinghong Zhu, Yi Shen, Xiangling Feng, Yongjun Guan, Chunmei Kuang, Jiaojiao Guo, Qian Lei, Yangbowen Wu, Gang An, Guancheng Li, Lugui Qiu, Fenghuang Zhan, Wen Zhou^*. NEK2 Induces Autophagy-mediated Bortezomib Resistance by Stabilizing Beclin-1 in Multiple Myeloma. Mol Oncol. 2020;14(4):763-778.

（6） Xuan Wu^#, Jiliang Xia^#, Jingyu Zhang, Yinghong Zhu, Yangbowen Wu, Jiaojiao Guo, Shilian Chen, Qian Lei, Bin Meng, Chunmei Kuang, Xiangling Feng, Yanjuan He, Yi Shen, Xin Li, Lugui Qiu, Guancheng Li^*, Wen Zhou^*. Phosphoglycerate dehydrogenase promotes proliferation and bortezomib resistance through increasing reduced glutathione synthesis in multiple myeloma. Br J Haematol. 2020;190(1):52-66. 

（7） Wendi Shuai^#, Jiangxue Wu^#, Shuai Chen, Ranyi Liu, Zhihua Ye, Chunmei Kuang, Xiang Fu, Gaoyuan Wang, Yingchang Li, Qihua Peng, Wei Shi, Yizhuo Li, Qianghua Zhou, Wenlin Huang*. SUV39H2 promotes colorectal cancer proliferation and metastasis via tri-methylation of the SLIT1 promoter. Cancer Lett. 2018;422:56-69. 

（8） Yingchang Li^#, Zhihua Ye^#, Shuai Chen, Zhiwen Pan, Qianghua Zhou, Yi-Zhuo Li, Wen-di Shuai, Chun-Mei Kuang, Qi-Hua Peng, Wei Shi, Xueli Mao, Ran-Yi Liu*, Wenlin Huang*. ARHGEF19 interacts with BRAF to activate MAPK signaling during the tumorigenesis of non-small cell lung cancer. Int J Cancer. 2018;142(7):1379-1391. 

（9） Zhu Y, Shi C, Zeng L, Liu G, Jiang W, Zhang X, Chen S, Guo J, Jian X, Ouyang J, Xia Jiliang, Kuang C, Fan S, Wu X, Wu Y, Zhou W^*, Guan Y^*. High COX-2 expression in cancer-associated fibiroblasts contributes to poor survival and promotes migration and invasiveness in nasopharyngeal carcinoma. Mol Carcinog. 2020 Mar;59(3):265-280.

（10） Xu H, Zeng L, Guan Y, Feng X, Zhu Y, Lu Y, Shi C, Chen S, Xia J, Guo J, Kuang C, Li W, Jin F, Zhou W^*. High NEK2 confers to poor prognosis and contributes to cisplatin-based chemotherapy resistance in nasopharyngeal carcinoma. J Cell Biochem. 2019;120(3):3547-3558.

（11） Wu-Ying Du, Zhen-Hai Lu, Wen Ye, Xiang Fu, Yi Zhou, Chun-Mei Kuang, Jiang-Xue Wu, Zhi-Zhong Pan, Shuai Chen, Ran-Yi Liu*, Wen-Lin Huang*. The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells. Chin J Cancer. 2017;36(1):11.

（12） Xiang Fu^#, Jiali Hu^#, Hong-yu Han^#, Yi-jun Hua^#, Ling Zhou, Wen-di Shuai, Wu-ying Du, Chun-mei Kuang, Shuai Chen, Wenlin Huang*, Ran-yi Liu*. High expression of XPA confers poor prognosis for nasopharyngeal carcinoma patients treated with platinum-based chemoradiotherapy. Oncotarget. 2015;6(29):28478-90. 

邮箱：kuangchm@csu.edu.cn