2015年本科毕业于南京大学。2020年博士毕业于南京大学，师从南京大学生命分析化学国家重点实验室鞠熀先教授，致力于近红外光响应纳米载体的设计合成及其癌症诊疗应用。2020年作为校特聘人才进入南京中医药大学药学院。

主要研究方向：1.智能响应型核酸纳米载体的制备及其在药物靶向递运与癌症诊疗领域中的应用；2. 设计开发通用型核酸探针，并探索其临床检测与生物成像方面的应用

成果论文：在Angew. Chem.等国际一流期刊发表文章10余篇。主持国家自然科学基金项目1项，江苏省自然科学基金项目1项，国家重点实验室开放基金1项。

[1] Yue Zhang, Xiaobo Zhang, Yuling He, Ying Liu*, Huangxian Ju*. Self-assembled micelle responsive to quick NIR light irradiation for fast drug release and highly efficient cancer therapy. Journal of Controlled Release 336 (2021) 469-479. (IF. 7.901).

[2] Yue Zhang#, Weiwei Chen#, Yue Zhang, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. A near-infrared photo-switched microRNA amplifier for precise photodynamic therapy of early-stage cancers. Angewandte Chemie-International Edition 59 (2020) 21454-21459. (IF: 12.257). 

[3] Yue Zhang, Yue Zhang, Guobin Song, Yuling He, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. A DNA-azobenzene nanopump fueled by upconversion luminescence for controllable intracellular drug release. Angewandte Chemie-International Edition 58 (2019) 18207-18211. (IF: 12.257). 

[4] Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu*, Huangxian Ju*. Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy. Biomaterials 163 (2018) 55-66. (IF: 10.273). 

[5] Kewei Ren#, Yue Zhang#, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. In situ siRNA assembly in living cells for gene therapy with microRNA triggered cascade reactions templated by nucleic acids. ACS Nano 12 (2018), 10797-10806. (IF: 13.903).

[6] Yue Zhang, Yue Zhang, Xiaobo Zhang, Yuyi Li, Yuling He, Ying Liu*, Huangxian Ju*. Photo zipper locked DNA nanomachine with internal standard for precise miRNA imaging in living cells. Chemical Science 11 (2020), 6289-6296. (IF: 9.556).

[7] Yuling He, Shuwen Guo, Yue Zhang, Ying Liu*, Huangxian Ju*. NIR-II reinforced intracellular cyclic reaction to enhance chemodynamic therapy with abundant H2O2 supply. Biomaterials 275 (2021) 120962. (IF: 10.273).

[8] Yuling He, Shuwen Guo, Yue Zhang, Ying Liu*, Huangxian Ju*. Near-infrared photo-controlled permeability of a biomimetic polymersome with sustained drug release and efficient tumor therapy. ACS Applied Materials & Interfaces 13 (2021) 14951-14963. (IF: 8.456).

[9] Yuyi Li, Xiaobo Zhang, Yue Zhang, Yue Zhang, Yuling He, Ying Liu*, Huangxian Ju*. Activatable photodynamic therapy with therapeutic effect prediction based on a self-correction upconversion nanoprobe. ACS Applied Materials & Interfaces 12 (2020) 19313-19323. (IF: 8.456).

[10] Lina Wu, Yingfei Wang, Rong He, Yue Zhang, Yuling He, Chao Wang, Zhenda Lu, Ying Liu*, Huangxian Ju*. Fluorescence hydrogel array based on interfacial cation exchange amplification for highly sensitive microRNA detection. Analytica Chimica Acta 1080 (2019) 206-214. (IF: 5.256).

[11] Kewei Ren, Ying Liu*, Jie Wu, Yue Zhang, Zhu Jing, Huangxian Ju*. A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery. Nature Communications 7 (2016) 13580. (IF: 12.353). 

[12] Kewei Ren, Jie Wu, Feng Yan, Yue Zhang, Huangxian Ju*. Immunoreaction-triggered DNA assembly for one-step sensitive ratiometric electrochemical biosensing of protein biomarker. Biosensors and Bioelectronics 66 (2015) 345-349. (IF: 8.173). 

[13] Kewei Ren, Jie Wu, Yue Zhang, Feng Yan, Huangxian Ju*. Proximity hybridization regulated DNA biogate for sensitive electrochemical immunoassay. Analytical Chemistry 86 (2014) 7494-7499. (IF: 6.042).