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2. Shen Y, Dinh HV, Cruz ER, Chen Z, Bartman CR, Xiao T, Call CM, Ryseck RP, Pratas J, Weilandt D, Baron H, Subramanian A, Fatma Z, Wu ZY, Dwaraknath S, Hendry JI, Tran VG, Yang L, Yoshikuni Y, Zhao H, Maranas CD, Wühr M*, Rabinowitz JD*. Mitochondrial ATP generation is more proteome efficient than glycolysis. Nat Chem Biol. 2024;20:1123-1132.

3. Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, White E, Rabinowitz JD*, Hogarty MD*, Morscher RJ*. Reprogramming neuroblastoma by diet-enhanced polyamine depletion. bioRxiv [Preprint]. 2024;

4. Sun W, Ren J, Jia Z, Liang P, Li S, Song M, Cao Y, Chen H, Luo Q, Yang L, Wang J, Wang C*, Wang L*. Untargeted Metabolomics Reveals Alterations of Rhythmic Pulmonary Metabolism in IPF. Metabolites. 2023;13:1069.

5. Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J*. Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. Basic Res Cardiol. 2023;118:47.

6. Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD*. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. 2023;614:349-357.

7. Zhao H#, Teng D#, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca di Magliano M, Boland GM, Flaherty KT, Swanson KD, Liu D, Rabinowitz JD, Zheng B*. Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth. Nat Metab. 2022;4:1660-1673.

8. Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, Von Hoff D, Guo JY, Han H, Rabinowitz JD*. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med. 2022;3:119-136.

9. Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD*. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022;13:158-172.

10. Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM*. Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods. 2022;19:223-230.

11. Zhang Z#, TeSlaa T#, Xu X, Zeng X, Yang L, Xing G, Tesz GJ, Clasquin MF, Rabinowitz JD*. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021;3:1608-1620.

12. Ghergurovich JM#, Xu X#, Wang JZ#, Yang L, Ryseck RP, Wang L, Rabinowitz JD*. Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab. 2021;3:1512-1520.

13. Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar MD, Gil Z, Diamond DJ, Rabinowitz JD, Rosen S, Melstrom LG*. Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int J Biol Sci. 2021;17:2240-2251.

14. Hui S#*, Cowan AJ#, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD*. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020;32:676-688.

15. Hui S#*, Cowan AJ#, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD*. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020;32:676-688.e4

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17. Achreja A#, Zhao H#, Yang L, Yun TH, Marini J, Nagrath D*. Exo-MFA - A 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism. Metab Eng. 2017;43:156-172.

18. Yang L, Venneti S, Nagrath D. Glutaminolysis: A Hallmark of Cancer Metabolism. Annu Rev Biomed Eng. 2017;19:163-194.

19. Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P*, Xu RH*, Chiao PJ*. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017;8:14437.

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21. Han C#, Yang L#, Choi HH#, Baddour J, Achreja A, Liu Y, Li Y, Li J, Wan G, Huang C, Ji G, Zhang X, Nagrath D*, Lu X*. Amplification of USP13 drives ovarian cancer metabolism. Nat Commun. 2016;7:13525.

22. Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK*, Nagrath D*. Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metab. 2016;24:685-700.

23. Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini JC, Tudawe T, Seviour EG, San Lucas FA, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, Ram PT, Maitra A, Nagrath D*. Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. Elife. 2016;5:e10250.

24. Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK*. Role of Increased n-acetylaspartate Levels in Cancer. J Natl Cancer Inst. 2016;108:djv426.

25. Mondal S, Roy D, Camacho-Pereira J, Khurana A, Chini E, Yang L, Baddour J, Stilles K, Padmabandu S, Leung S, Kalloger S, Gilks B, Lowe V, Dierks T, Hammond E, Dredge K, Nagrath D, Shridhar V*. HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer. Oncotarget. 2015;6:33705-19.

26. Nicolaou KC*, Nilewski C, Hale CR, Ahles CF, Chiu CA, Ebner C, ElMarrouni A, Yang L, Stiles K, Nagrath D. Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents. J Am Chem Soc. 2015;137:4766-70.

27. Köhring M*, Huang S, Jahjah V, Jiang W, Ren W, Willer U, Caneba C, Yang L, Nagath D, Schade W, Tittel FK*. QCL-based TDLAS sensor for detection of NO toward emission measurements from ovarian cancer cells. Applied Physics B, 2014;117:445–451. 

28. Caneba CA#, Yang L#, Baddour J, Curtis R, Win J, Hartig S, Marini J*, Nagrath D*. Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death Dis. 2014;5:e1302.

29. Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, Roopaimoole R, Rodriguez-Aguayo C, Mercado-Uribe I, Lopez-Berestein G, Liu J, Tsukamoto T, Sood AK, Ram PT, Nagrath D*. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer. Mol Syst Biol. 2014;10:728.

30. Caneba CA, Bellance N, Yang L, Pabst L, Nagrath D*. Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration. Am J Physiol Endocrinol Metab. 2012;303:E1036-52.

31. Komurov K, Tseng JT, Muller M, Seviour EG, Moss TJ, Yang L, Nagrath D*, Ram PT. The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells. Mol Syst Biol. 2012;8:596.

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