6062
当前位置: 首页   >  成果及论文
成果及论文

28. Sarah Cherkaoui, Lifeng Yang, Matthew McBride, Christina S. Turn, Wenyun Lu, Caroline Eigenmann, George E. Allen, Olesya O.          

      Panasenko, Lu Zhang, Annette Vu, Kangning Liu, Yimei Li, Om H. Gandhi, Lea Surrey, Michael Wierer, Eileen White, Joshua D. 

      Rabinowitz*, Michael D. Hogarty* and Raphael J. Morscher* Reprogramming neuroblastoma by diet-enhanced polyamine depletion.

27. Bartman, C. R., Weilandt, D. R., Shen, Y., Lee, W. D., Han, Y., TeSlaa, T., Jankowski, C. S. R., Samarah, L., Park, N. R., da Silva-Diz, V., Aleksandrova, M., Gultekin, Y., Marishta, A., Wang, L., Yang, L., Roichman, A., Bhatt, V., Lan, T., Hu, Z., Xing, X., Lu, W., Davidson, S., Wühr, M., Vander Heiden, M. G., Herranz, D., Guo, J. Y., Kang, Y., Rabinowitz, J. D. (2023) Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature, doi: 10.1038/s41586-022-05661-6.

26. Zhao, H., Teng, D., Yang, L., Xu, X., Chen, J., Jiang, T., Feng, A. Y., Zhang, Y., Frederick, D. T., Gu, L., Cai, L., Asara, J. M., Pasca di Magliano, M., Boland, G. M., Flaherty, K. T., Swanson, K. D., Liu, D., Rabinowitz, J. D., Zheng, B. (2022) Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth. Nat Metab., Nov 14.

25. Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J.D. (2022) Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med (N Y), 3:119-136.

24. Nofal, M., Wang, T., Yang, L., Jankowski, C. S. R., Hsin-Jung, L. S., Han, S., Parsons, L., Frese, A. N., Gitai, Z., Anthony, T. G., Wühr, M., Sabatini, D. M., Rabinowitz, J. D. (2022) GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst., 13: 158-172.

23. Wang, L., Xing, X., Zeng, X., Jackson, S. R., TeSlaa, T., Al-Dalahmah, O., Samarah, L. Z., Goodwin, K., Yang, L., McReynolds, M. R., Li, X., Wolff, J. J., Rabinowitz, J. D., Davidson, S. M. (2022) Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods, 19: 223-230.

22. Zhang, Z., TeSlaa, T., Xu, X., Zeng, X., Yang, L., Xing, G., Tesz, G. J., Clasquin, M. F., Rabinowitz, J. D. (2021) Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab., 3: 1608-1620.

21. Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R. P., Wang, L., Rabinowitz, J. D. (2021) Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab., 3: 1512-1520.

20. Phan, T., Nguyen, V. H., Buettner, R., Morales, C., Yang, L.Wong, P., Tsai, W., d'Alincourt Salazar, M., Gil, Z., Diamond, D. J., Rabinowitz, J. D., Rosen, S., Melstrom, L. G. (2021) Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int. J. Biol. Sci., 17: 2240-2251.

19. Hui, S#., Cowan, A. J#., Zeng, X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D. Quantitative fluxomics of circulating metabolites. Cell Metab., 32: 676-688.e4. 2020

18. Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, Morscher RJ, Rabinowitz JD. Serine catabolism feeds NADH when respiration is impaired, Cell Metabolism, 2020

17. Lin Wang, Xi Xing, Li Chen, Lifeng Yang, et.al., Peak annotation and verification engine(PAVE) for untargeted LC-MS metabolomics, Analytical Chemistry, 2018

16. Abhinav Achreja, Hongyun Zhao, Lifeng Yang, et.al., Exo-MFA 13C dynamic metabolic flux analysis method to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism, Metabolic Engineering, 2017.

15. Lifeng Yang, Sriram Venneti, Deepak Nagrath, Glutaminolysis: A Hallmark of Cancer Metabolism, Annual Review of Biomedical Engineering, 2017.

14. HQ Ju, H Ying, T Tian, J Ling, J Fu, Y Lu, M Wu, L Yang, et.al., Mutant Kras-and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma, Nature communication, 2017

13. Presenjit Dey, Joelle Baddour, Florian Muller, Chia Chin Wu, Huamin Wang, Wen-Ting Liao, Zangdao Lan, Nikunj Satani, Andrea Viale, Haoqiang Ying, Di Zhao, Abhinav Achreja, Lifeng Yang, et.al., Genomic Deletion of Malic Enayme 2 Confers Collateral Letheality in Pancreas Cancer, Nature, 2017

12. Cecil Han*, Lifeng Yang*, Hyunho Choi*, et.al., Amplification of USP13 Promotes Ovarian Cancer Cell Metabolism and Tumor Progression, Nature Communications (* Equal Contribution), 2016

11. Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, et.al., Targeting Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-regulated Cancer Cell Growth, Cell Metabolism, 2016

10. Hongyun Zhao, Lifeng Yang, Joelle Baddour, et.al., Tumor Microenvironment Derived Exosomes Pleiotropically Regulate Cancer Cell Metabolism, 2016. eLife

9. Behrouz Zand, Rebecca A Previs, Niki M Zacharias, Rajesha Rupaimoole, Takashi Mitamura, Archana Sidalaghatta Nagaraja, Michele Guindani, Heather J Dalton, Lifeng Yang, et.al., Role of Increased n-acetylaspartate Levels in Cancer, Journal of the National Cancer Institute, 2016

8. S Mondal, D Roy, J Camacho-Pereira, A Khurana, E Chini, L Yang, et.al.,HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer, Oncotarget, 2015

7. KC Nicolaou, Christian Nilewski, Christopher RH Hale, Christopher F Ahles, Chiao An Chiu, Christian Ebner, Abdelatif ElMarrouni, Lifeng Yang, et.al., Synthesis and Biological Evaluation of Dimeric Furanoid Macroheterocycles: Discovery of New Anticancer Agents, Journal of the American Chemical Society, 2015

6. M Köhring, S Huang, M Jahjah, W Jiang, W Ren, U Willer, C Caneba, L Yang, et.al., QCL-based TDLAS sensor for detection of NO toward emission measurements from ovarian cancer cells, Applied Physics B, 2014

5. Christine A. Caneba*, Lifeng Yang*, Joelle Baddour, et.al., Nitric Oxide is a Postive Regulator of the Warburg Effect in Ovarian Cancer Cells, Cell Death & Diseases, 2014 (* Equal Contribution)

4. Lifeng Yang, Tyler Moss, Lingegowda S. Mangala, et.al., Metabolic shifts toward glutamine regulates tumor growth, invasion and bioenergetics in ovarian cancer, Molecular Systems Biology, 2014

3. Christine Caneba, Nadège Bellance, Lifeng Yang, et.al., Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function and migration, American Journal of Physiology Endocrinology and Metabolism, 2012

2. K Komurov, JT Tseng, M Muller, EG Seviour, TJ Moss, L Yang, et.al., The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells, Molecular System Biology, 2012

1. K Zhang, X Li, Y Ma, S Zou, L Yang, et.al, A curve fitting method of quantifying green fluorescent protein expression level in Escherichia coli, Journal of microbiological methods, 2010