教育背景：
2004.9-2008.7：中国科学院上海生命科学研究院植物生理生态研究 所与西安交通大学联合培养，生物化学与分子生物学专业，博士。
2001.9-2004.8：西安交通大学，生物化学与分子生物学专业，硕士1997.9-2001.8: 西安工程大学，纺织工程，学士。
工作经历：
1. 2017.12-现在: 副研究员，中国科学院上海营养与健康研究所，从事肝肿瘤及其肿瘤免疫、糖尿病等代谢性疾病的代谢与调控机制的研究。
2. 2013.7-2017：助理研究员，中国科学院上海生命科学研究院营养科学研究所，从事代谢酶ALDOB等作为抑癌基因，通过上调磷酸戊糖（PPP）代谢途径促进肝肿瘤的发展的研究。
3. 2010.6-2012.8：博士后，Sanford-Burnham Medical Research Institute（La Jolla, CA ,USA)癌症中心做博士后，开展蛋白酶PKCZ激活serine代谢途径并促进其大肠癌发展的研究。
4. 2008.9-2010.5: 博士后，中国科学院上海生命科学研究院植物生理生态研究所，从事微生物产氢的生物能源的研究。
科研兴趣：
主要从事乳腺癌、大肠癌和肝癌等肿瘤及其糖尿病等代谢性疾病的代谢组学及其信号传导的分子调控机制的研究。目前主要聚焦于肝癌、肝肿瘤微环境的免疫代谢及其调控的信号分子机制的研究。我基于现代质谱技术的代谢组学和脂质组学平台，发展了稳定同位素的13C-flux代谢流量技术和代谢组学方法相结合，深层次的实时示踪代谢性疾病（如癌症、糖尿病、肥胖等）病人组织、血液、尿液及其小鼠各组织和细胞胞内的代谢变化及其分子调控机制。其主要研究成果在Cell、 Nature cancer、Hepatology、Redox biology、JBC等重要期刊上，共发表20多篇研究文章.
已发表文章：
1.Chunzhao Yin, cunzhen zhang,yongqiang wang,guijun liu, ningning wang, ningning liang,lili zhang,Qiaochu Tu,jingwen lv, huimin jiang,haoran ma chenxi du,Min Li, xuxiao he,shiting chen,Jiacheng Guo,shengxian li,Jun Qin,Nan Li,Yongzhen Tao, Huiyong Yin. ALDOB/KAT2A interactions epigenetically modulate TGF-β expression and T cell functions in hepatocellular carcinogenesis. Hepatology, Under Review, 2023. (共同通信)。
2.Guijun Liu, Ningning Wang, Cunzhen Zhang, Min Li, Xuxiao He, Chunzhao Yin, Qiaochu Tu, Xia Shen, Lili Zhang, Jingwen Lv, Yongqiang Wang, Huimin Jiang, Shiting Chen, Nan Li, Yongzhen Tao*, Huiyong Yin*. ALDOB Depletion Promotes Hepatocellular Carcinogenesis through Activating Insulin Receptor Signaling and Lipogenesis. Hepatology, Vol 74, NO.6, 2021.(共同通讯作者, IF=17.74).
3. Yabo Jiang#, Yongzhen Tao #, Xiuping Zhang# , Xubiao Wei , Min Li , Xuxiao He , Bin Zhou1 , Weixing Guo , Huiyong Yin and Shuqun Cheng Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma. Molecular Oncology,15, P710-724, 2021.(共同第一作者，IF:6.985).
4. Min Li, Xuxiao He, Weixing Guo, Hongming Yu, Shicheng Zhang 4, Ningning Wang,Guijun Liu, Rina Sa, Xia Shen, Yabo Jiang, Yufu Tang, Yujuan Zhuo, Chunzhao Yin, Qiaochu Tu, Nan Li, Xiaoqun Nie, Yu Li, Zhimin Hu, Hanwen Zhu, Jianping Ding , Zi Li, Te Liu, Fan Zhang,He Zhou, Shengxian Li, Jiang Yue, Zheng Yan, Shuqun Cheng, Yongzhen Tao* and Huiyong Yin*. Nature Cancer. Volume 1, p735-747, 2020.（共同通讯作者, Nature Cancer, IF=23.17.）
5. Ningning Wang, Hongzhi Liu, Guijun Liu, Min Li, Xuxiao He, Chunzhao Yin,
Qiaochu Tu, Xia Shen, Wenqiang Bai, Qiang Wang, Yongzhen Tao*, Huiyong Yin*. Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis. Redox Biology. Volume 32, 101495, p1-14, 2020. (共同通讯作者, IF=11.346).
6. Guijun Liu , Aimin Shi, Ningning Wang, Min Li, Xuxiao He , Chunzhao Yin ,Qiaochu Tu , Xia Shen , Yongzhen Tao ,***, Qiang Wang ,**, Huiyong Yin*** .Polyphenolic Proanthocyanidin-B2 suppresses proliferation of liver cancer cells and hepatocellular carcinogenesis through directly binding and inhibiting AKT activity. Redox Biology. Volume 37, 101701, p1-13, 2020. (共同通讯作者, IF=11.346）
7. Xuxiao He , Min Li , Hongming Yu, Guijun Liu , Ningning Wang , ChunzhaoYin , Qiaochu Tu , Goutham Narla Narla, Yongzhen Tao Tao* , Shuqun Cheng Cheng* and Huiyong YinYin*. Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing Aldob/Akt/PP2A protein complex. Plos Biology, 2020. (共同通讯作者, IF=7.067）
8. Shengxian Li#, JiaQi,#, Yongzhen Tao,# Qinling Zhu, Rong Huang, Yu Liao, Jiang Yue, Wei Liu, Hanting Zhao, HuiyongYin, and Yun Sun. Elevated levels of arachidonic acid metabolites in follicular fluid of PCOS patients. Reproduction. Volue,159, p159-169,2020.(共同第一作者，IF:5.585).
9. Shanshan Zhong, Luxiao Li , Yu-Lei Zhang, Lili Zhang , Jianhong Lu, Shuyuan Guo , Ningning Liang , Jing Ge , Mingjiang Zhu , Yongzhen Tao, Yun-Cheng Wu , Huiyong Yin. Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation. The Journal of Clinical Investigation.129(1), p252-267,2019. (其他作者).
10. Hongli Hu, Wenwei Zhu , Jun Qin, Min Chen, Liyan Gong, Long Li, Xiangyuan Liu , Yongzhen Tao, Huiyong Yin, Hu Zhou, Lisha Zhou, Dan Ye, Qinghai Ye, Daming Gao. Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis. HEPATOLOGY, VOL. 65, NO. 2, ,p515-528, 2017. (其他作者).
11. Fay J. Dufort‡, Maria R. Gumina‡1, Nathan L. Ta, Yongzhen Tao, Shannon A. He, David A. Scott,Adam D. Richardson, Thomas N. Seyfried, and Thomas C. Chiles. Glucose-dependent de Novo Lipogenesis in B Lymphocytes. J. Biol. Chem,Vol 289,No.10,p7011-7024 ,2014. (其他作者）
12. Li Ma, Yongzhen Tao, Angeles Duran,.,et al. Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCz in Tumorigenesis. Cell , Volume 152, p599-611, 2013. (第二作者）
13. Yongzhen Tao, Deng Liu, et al. Network Identification and Flux Quantification of Glucose Metabolism in Rhodobacter sphaeroides under Photoheterotrophic H2-Producing Conditions. Journal of Bacteriology, 2012, 194(2): 27-283. (IF: 3.825).
14.Yongzhen Tao, Yanling He,Yongqiang Wu, Fanghua Liu, and Zhihua Zhou. Characteristics of a new photosynthetic bacterial strain for hydrogen production and its application in wastewater treatment. International Journal of Hydrogen Energy. 2008, 33(1): 963-973. (IF: 4.42).
15. Yongzhen Tao, Yang Chen, Yongqiang Wu, Yanling He, and Zhihua Zhou. High hydrogen yield from a two-step process of dark-and photo fermentation of sucrose. International Journal of Hydrogen Energy. 2007, 32 (2): 200-206. (IF: 4.054).