Baixing Wu is mainly engaged in the structural biology research of nucleic acid-related proteins using X-ray crystallography and Cryo-EM technology, combined with biochemical and molecular biology methods.
Including:
1) Catalysis and recognition mechanism of RNA/DNA modification;
2) Structure and function of diseases-related and non-coding RNA biogenesis associated RNA-binding proteins;
3) The DNA replication and damage repair;
4) The metabolic mechanism of nucleoside-modified nucleic acids.