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成果及论文

1.成果:  

  本团队致力于心血管疾病治疗的新型生物医用材料和医疗器械的应用基础研究与产品开发,立足于心血管医疗器械的临床需求,以新型生物材料研发为基础,结合血流动力学研究力学仿真模拟及机械设计,优化相关产品的关键参数,与企业及医院合作,进行大规模动物实验及临床试验验证,形成材料研发-力学设计-产品开发-临床验证全链条研发机制,最终实现相关心血管医疗器械的大规模产业化应用。

  团队主要研究方向为用于心血管疾病治疗和修复的经导管微创介入心脏瓣膜、血管支架、抗心衰材料、儿童先心病封堵器械以及人工心肺机(ECMO)等应用基础研究和产品开发。最近几年中,作为项目首席或课题负责人承担国家重点研发计划7项、国家自然科学基金13项、四川省重大科技项目3项、校企合作项目15项。团队已发表SCI论文200多篇,申报国内外专利500多项,与企业合作开发产品获得注册证10项,主编和参编专著6本。获教育部技术发明一等奖(2020)、四川省科技进步一等奖(2022)和中国侨界贡献一等奖(2020)等奖项。

     团队与企业医院合作研发的全降解心脏封堵器系统于2022年2月正式获批上市大规模临床使用,实现了“介入无植入,植入无残留”的健康理念,让先心病患儿和正常孩子一样健康成长,标志着先心病封堵器械正式进入可降解修复时代;微创介入自膨式肺动脉瓣膜系统,已在英国、德国、加拿大等20个国家和地区50多个医学中心进行了临床应用,具有良好的安全性和有效性,挽救了患者的生命,2022年4月在欧盟正式获批上市使用,2022年6月成功应用于美国患者人道救治使用,2022年7月在国家药监局正式获批上市使用。团队自主研发出特殊多臂嵌段式材料,开发出自主创新的ECMO系统长效抗凝涂层核心技术,具有良好的韧性及抗凝功能,已申报多项国家发明专利。在此基础上,完成了全套国产化ECMO样机制备,有望大幅降低治疗费用,造福更多患者。

  团队与国内心血管领域企业、医院建立了稳定的产学研医合作,引领国内心血管材料及器械的发展,已成为该领域国内外知名且具有鲜明特色的心血管材料及器械工科研究团队。

  除此之外,本团队在基于纳米材料和人工智能的各类疾病快速筛查的液体活检技术研究、基于柔性生物电子材料的智能医疗器械产品研发、和基于新型生物材料的糖尿病连续性血糖检测技术开发等方面也取得了较好进展和一系列成果

2.文章发表:

2024年:

309. Wu H, Yang L, Luo R, Li L, Zheng T, Huang K, Qin Y, Yang X, Zhang X, Wang Y. (2024). A Drug-free Cardiovascular Stent Functionalized with Tailored Collagen Supports in-situ Healing of Vascular Tissues. Nature Communications. 15(1), 735. (中科院一区,IF:17.7) 

308. Ren X, Zhang J, Yang F, Xu H, Guo G, Wang Y. (2024). Enzyme-Immobilized Surface-Catalyzed Crosslinking: Creating Multifunctional Double Network Hydrogel Coatings on Diverse Substrates. Advanced Functional MaterialsAccepted.  (一区,IF:19.9) 

307. Li L, Cao Z, Zhang C, Li L, Li Q, Liu C, Qu C, Luo R, Fu P, Wang Y. (2024). A Versatile Passivated Protein-Adsorption Platform for Rapid Healing of Vascular Stents by Modulating the Microenvironment. Advanced Functional Materials. 2312243.  (一区,IF:19.9)  

306. Li L, Zhang C, Cao Z, Ma L, Liu C, Lan X, Fu P, Luo R, Wang Y. (2024). Passivation Protein-adhesion Platform Promoting Stent Reendothelialization Using Two-Electron-Assisted Oxidation of Polyphenols. Biomaterials305, 122423.  (一区,IF:15.3)

305. Zhao Z, Xu H, Li A, Pu H, She P, Li G, Wang Y. (2024). Enalaprilat-loaded polyphenol nanoparticle composite hydrogel promotes myocardial protection after acute infarction. Composites Part B: Engineering. 111430. (一区,IF:11.3

304. Fu D, Xiang Y, Xiang Z, Zhang J, Yang F, Yang L, Zhao J, Wang Y. (2024). Optimizing Small-Diameter Vascular 1 Grafts: Harnessing the Power of Recombinant Human Type III Collagen (rhCOLIII) for Enhanced Antiplatelet and Endothelialization Performance. Chemical Engineering Journal. Accepted. (一区,IF:16.7) 

303. Yan H, Wang L, Wu H, An YQin Y, Xiang Z, Wan H, Tan Y, Yang L, Zhang F, Jiang Q, Luo R, Wang Y. (2024). Anti-fouling coating with ROS-Triggered On-Demand regulation of inflammation to favor tissue healing on vascular devices. Chemical Engineering Journal. 151893. (一区,IF:16.7) 

302. Zhang H, Wang B, Han J, Shen X, Sun Q, An Y, Luo R, Wang Y. (2024). A self-healing coating with embedding of polyphenols on magnesium: Towards enhanced corrosion protection for biodegradable vascular implants. Chemical Engineering Journal. 482, 149020. (一区,IF:16.7) 

301. Zhang J, Xiang Z, Ren X, Zhang B, Fu D, Wang Y. (2024). Superior Toughness Anticorrosion-Bioactive Integrated Multilayer Coating with Excellent Adhesion for Biodegradable Magnesium-Based Stents. Chemical Engineering Journal. 481, 148400(一区,IF:16.7) 

300. Xie R, Fu S, Zhu G, Ai H, Song B, Lui S, Li G, Wang Y, Wu M. (2024). Iron Oxide Nanoclusters Formed by Acid-Induced in situ Calcium Ion Cross-Linking for Targeted Magnetic Resonance Imaging of Glioblastoma. Chemical Engineering JournalAccepted.  (一区,IF:16.7)  

299. Wei Y, Fan X, Liu J, Chen C, Dong R, Zhang H, Yang L, Luo R, Zhang F, Wang Y. (2024). A Photo-triggered Coating of Prosthetic Valve Leaflet Surface to Realize Antibacterial and Thrombolysis on-demand. Chemical Engineering Journal. 479, 147438. (一区,IF:16.7) 

298. Zhang L, Zhou L, Wang K, Shang T, Liu Y, Wang Y, Zhao Y, Huang N, Luo R, Li X, Wang J. (2024). GPx-like phenolic-amine nanoparticles with onion peel-off model for constantly generative anti-inflammation and anti-oxidation capability. Chemical Engineering Journal. 150290. (一区,IF:16.7)

297. Zhang W, Liu Y, Wang Z, He S, Liu W, Wu Y, Yang L, Hu C, Wang Y. (2024). Remodeling Brain Pathological Microenvironment to Lessen Cerebral Ischemia Injury by Multifunctional Injectable Hydrogels. Journal of Controlled Release. Accepted. (一区,IF:11.5)

296. Liu W, Hu C, Long L, He S, Zhang W, Wang Z, Yang L, Wang Y. (2024). An injectable carrier for spatiotemporal and sequential release of therapeutic substances to treat myocardial infarction. Journal of Controlled Release365, 29-42.(一区,IF:11.5)

295. Li L, Sun C, Zhou Y, Zhou Z, Zhang J, Xu Y, Xiao X, Li G, Chen Z, Deng H, Hu X, Wang Y (2024). Fully integrated wearable microneedle biosensing platform for wide-range long term continuous glucose monitoring. Acta Biomaterialia175, 199-213.(一区,IF:10.6

294. Chen Z, Li L, Xiao X, Zhang Y, Zhang J, Jiang Q, Hu X, Wang Y. (2024). Used tissue paper as a 3D substrate for non-enzyme glucose sensors. Green Chemistry. Accepted. (一区,IF: 9.8)

293. Ge Z, Long L, Zhang F, Dong R, Chen Z, Tang S, Yang L, Wang Y. (2024). Development of an injectable oxidized dextran/gelatin hydrogel capable of promoting the healing of alkali burn-associated corneal wounds. International Journal of Biological Macromolecules. 132740.  (一区,IF: 8.2) 

292. Pu H, Wang C, Yu T, Chen X, Li G, Zhu D, Pan X, Wang Y. (2024). A synergistic strategy based on active hydroxymethyl amine compounds and fucoidan for bioprosthetic heart valves with enhancing anti-coagulation and anti-calcification properties. International Journal of Biological Macromolecules. 130715. (一区,IF: 8.2) 

291. Zhou Y, Du W, Chen Y, Li L, Xiao X, Xu Y, Yang W, Hu X, Wang B, Zhang J, Jiang Q, Wang Y. (2024). Pathogen Detection via Inductively Coupled Plasma Mass Spectrometry Analysis with Nanoparticles. Talanta. 276. 126325.  (一区,IF: 6.5)

290. Zhuang W, Li J, Qu T, Shao R, Chen J, Li S, Chen M, Wang Y. (2024). A lipid activated color switchable probe for the imaging of diseased aortic valves. Talanta. 275, 126069. (一区,IF: 6.5)

289. Zhang T, Dou Y, Li Y, Luo R, Yang L, Zhang W, Wang Y, Zhang X. (2024). Design and performance of double-layered artificial chordae. Regenerative Biomaterials. rbae076. (一区,IF: 5.8)

288. Wu H, Chen N, Zheng T, Li L, Hu M, Qin Y, Guo G, Yang L, Wang Y. (2024). A strategy for mechanically integrating robust Hydrogel-Tissue hybrid to promote the anti-calcification and endothelialization of bioprosthetic heart valve. Regenerative Biomaterials. 11, rbae003. (一区,IF: 5.8)

287. Guo X, Ma Y, Wang H, Yin H, Shi X, Chen Y, Gao G, Sun L, Wang J, Wang Y, Fan D. (2024). Status and Developmental Trends in Recombinant Collagen Preparation Technology. Regenerative Biomaterials. 11, rbad106. (一区,IF: 5.8)

286. Zheng C, Yang L, Wang Y. (2024). Recent progress in functional modification and crosslinking of bioprosthetic heart valves.  Regenerative Biomaterials. 11, rbad098.  (一区,IF: 5.8)

285. Liu W, Long L, Wang Z, He S, Han , Yang L, Hu C, Wang Y (2024). A Whole-Course-Repair System Based on Stimulus-Responsive Multifunctional Hydrogels for Myocardial Tissue Regeneration. Small Methods(二区,IF: 15.3

284. Zhou Y, Tang Z, Li L, Chen Y, Xu Y, Liu R, Zhang Y, Liu X, Yang W, Wang B, Zhang J, Jiang Q, Wang Y. (2024). Highly sensitive detection of Salmonella typhimurium via gold and magnetic nanoparticle-mediated sandwich hybridization coupled with ICP-MS. Journal of Materials Chemistry BAccepted. (二区,IF: 7.6

283. Zhou Y, Li L, Tong J, Chen X, Deng W, Chen Z, Xiao X, Yin Y, Zhou Q, Gao Y, Hu X, Wang Y. (2024). Advanced nanomaterials for electrochemical sensors: application in wearable tear glucose sensing technology. Journal of Materials Chemistry BAccepted. (二区,IF: 7.6

282. Deng W, Zhou Y, Wan Q, Li L, Deng H, Yin Y, Zhou Q, Li Q, Cheng D, Hu X, Wang Y. (2024). Nano-enzyme hydrogels for cartilage repair effectiveness based on ternary strategy therapy. Journal of Materials Chemistry B. Accepted. (二区,IF: 7.6

281. Li L, Wang T, Zhong Y, Li R, Deng W, Xiao X, Xu Y, Zhang J, Hu X, Wang Y. (2024). A Review of Nanomaterials for Biosensing Applications. Journal of Materials Chemistry B12, 1168-1193. (二区,IF: 7.6

280. Chen Y, Jing Q, Zhang Y, Wu X, Bai Z, Dan N, Li Z, Li Y, and Wang Y. (2024). Facile Double-Injection Strategy for the Engineering of Versatile Multiresponsive Hydrogels Encapsulating Drug-Loaded Micelles for Promoting Diabetic Wound Healing. Industrial & Engineering Chemistry Research. Accepted. (三区,IF: 4.3

279. Wang B, Gao C, Lim S, Wang R, Zhu C, Onuma Y, Wang Y, Gao R, Serruys P, Lee R, Tao L. (2024). Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study. Journal of Cardiovascular Translational Research. Accepted.(三区,IF: 3.4

278. Xu Y, Luo W, Deng H, Hu X, Zhang J, Wang Y. (2024). Robust antibacterial activity of rare-earth ions on planktonic and biofilm bacteria. Biomedical Materials. Accepted. (三区,IF:3.7)

277. Uludag H, Wang Y, Vrana E, Tamerler C, Kothapalli C, Vasudev M. (2024). Insights In Biomaterials 2022/2023: Novel Developments, Current Challenges and Future Perspectives. Frontiers in Bioengineering and Biotechnology12, 1364724. (二区,IF:6.1) 

2023年:

276. Xu H, She P, Zhao Z, Ma B, Li G, Wang Y. (2023). Duplex Responsive Nanoplatform with Cascade Targeting for Atherosclerosis Photoacoustic Diagnosis and Multichannel Combination Therapy. Advanced Materials. 35(21), 2300439. (中科院一区IF:32.1) 

275. Ma B, Xiao Y, Lv Q, Li G, Wang Y, Fu G. (2023). Targeting Theranostics of Atherosclerosis by Dual-Responsive Nanoplatform via Photoacoustic Imaging and Three-In-One Integrated Lipid Management.  Advanced Materials. 35(5), 2206129. (一区IF:32.1) 

274. Ma B, Chen Z, Xu H, Sun S, Huang C, Li G, Zhang W, Shang M, Wang Y, Fu G. (2023).  Biomimetic Targeting Nanoplatform for Atherosclerosis Theranostics via Photoacoustic Diagnosis and “Hand-In-Hand” Immunoregulation. Advanced Functional Materials. 2311305. (一区IF:19.9) 

273. Wu Y, Wang Y, Zheng C, Hu C, Yang L, Kong Q, Zhang H, Wang Y. (2023). A Versatile Glycopeptide Hydrogel Promotes Chronic Refractory Wound Healing Through Bacterial Elimination, Sustained Oxygenation, Immunoregulation, and Neovascularization. Advanced Functional Materials. 33(49), 2305992 (一区IF:19.9) 

272. Zhang B, Wan H, Liu X, Yu T, Yang Y, Dai Y, Xu K, Han Y, Yang L, Wang Y, Zhang X. (2023). Engineering Immunomodulatory Stents Using Zinc Ion-Lysozyme Nanoparticle Platform for Vascular RemodelingACS Nano. 17(23), 23498–23511. (一区,IF:18.0)

271. Wan H, Li Y, Qin Y, An Y, Yan H, Liu X, Zhang H, Hu C, Li L, Fu D, Yang Y, Dai Y, Luo R, Yang L, Zhang B, Wang Y. Polyphenol-mediated sandwich-like coating promotes endothelialization and vascular healing. Biomaterials. 302, 122346.  (一区,IF:15.3)

270. Li Y, Wan H, Qin Y, Yan H, An Y, Liu X, Luo R, Yang Y, Dai Y, Yang L, Zhang B, Wang Y. (2023). A bio-inspired nanoparticle coating for Vascular Healing and Immunomodulatory by cGMP-PKG and NF-kappa B signaling pathways. Biomaterials.  302, 122288 (一区,IF:15.3)

269. Wang Y, Wu Y, Zhang B, Zheng C, Hu C, Guo C, Kong Q, Wang Y. (2023).  Repair of Degenerative Nucleus Pulposus by Polyphenol Nanosphere Encapsulated Hydrogel Gene Delivery System. Biomaterials298, 122132.  (一区,IF:15.3)

268. Yu T, Li G, Chen X, Kuang D, Jiang Q, Guo Y, Wang Y. (2023). A versatile drug-controlled release polymer brush hybrid non-glutaraldehyde bioprosthetic heart valves with enhanced anti-inflammatory, anticoagulant and anti-calcification properties, and superior mechanical performance. Biomaterials. 296,122070. (一区,IF:15.3)

267. Wu C, Zhang Y, Xu Y, Long L, Hu X, Zhang J, Wang Y. (2023). Injectable polyaniline nanorods/alginate hydrogel with AAV9-mediated VEGF overexpression for myocardial infarction treatment. Biomaterials. 296,122088.  (一区,IF:15.3)

266. Wang S, Li Z, Wang Y, Zhao T, Mo X, Fan T, Li J, You T, Deng R, Ouyang W, Wang W, Zhang C, Butera G, Hijazi Z, Pang K, Zhu D, Jiang S, Zhang G, Hu X, Xie Y, Zhang F, Fang F, Sun J, Li P, Chen J, Luo Z, Pan X. (2023). Transcatheter Closure of Perimembranous Ventricular Septal Defect by A Novel Fully Bioabsorbable Occluder: 24 months results of a randomized controlled trial. Science Bulletin.  68(10), 1051-1059.   (一区,IF:20.6)  

265. Li L, Xu Y, Chen Z, Zhang J, Xiao X, Deng H, Zhou Y, Li G, Hu X, Wang Y. (2023). Covalently bridge metals to biomass carbon for sensing DA and FA with high specificity and sensitivity. Chemical Engineering Journal. 477, 146650. (一区,IF:16.7) 

264. Wang Z, Hu C, Zhang W, Liu W, He S, Wu D, Yang Y, Wang Y. (2023). An injectable ECM-like hydrogel with bioactive peptides and RepSox nanoparticles for myocardial infarction treatment. Chemical Engineering Journal. 474, 145878 (一区,IF:16.7) 

263. He S, Long L, Wang Z, Liu W, Zhang W, Hu C, Wu X, Dong R, Fan H, Jiang Q, Tong Y, Yang G, Yang L, Wang Y. (2023). Combining HUMSC secretome and a conductive hydrogel enhances angiogenesis and electrical transmission at myocardial infarct sites to support cardiac repair. Chemical Engineering Journal. 474, 145877 (一区,IF:16.7) 

262. Long L, Ge Z, Zhang F, Dong R, Yang L, Chen Z, Tang S, Wang Y. (2023). Development of injectable hyaluronic acid-based hydrogels with antioxidant activity for the treatment of corneal neovascularization. Chemical Engineering Journal 478, 147147.  (一区,IF:16.7) 

261. Liang X, Hu C, Wang Y. (2023). Biomimetic-modified bioprosthetic heart valves with controlled release of glycyrrhizin acid mediated by the inflammatory microenvironment for anti-thrombotic, anti-inflammatory, and anti-calcification. Chemical Engineering Journal.  472, 145044.  (一区,IF:16.7) 

260. Chen C, Li L, Qin Y, Yu T, Luo R, Chen Y, Jiang W, Xu T, Han Y, Wang Y (2023). One-pot Deposition of a Multi-Functional Biomimetic Coating for Vascular Stents. Chemical Engineering Journal. 464, 142605.  (一区,IF:16.7)  

259. Yang F, Guo G, Wang Y. (2023). Inflammation-directed nanozyme-eluting hydrogel coating promotes vascular tissue repair by restoring reactive oxygen species homeostasis. Chemical Engineering Journal. 454, 140556. (一区,IF:16.7) 

258. Zhang B, Qin Y, Li Y, Wang Y, Wan H, Liu X, Hu X, An Y, Zhang H, Yang L, Luo R, Wang Y. (2023). Design and Efficacy of All-in-one Sandwich-like Multifunctional Platform for Drug Delivery. Chemical Engineering Journal. 452, 139367. (一区,IF:16.7

257. Zhang Y, Wu C, Xu Y, Chen Z, Li L, Chen J, Ning N, Guo Y, Yang Z, Hu X, Zhang J, Wang Y. (2023). Conductive Hydrogels with Hierarchical Biofilm Inhibition Capability Accelerate Diabetic Ulcer Healing . Chemical Engineering Journal. 463, 142457.(一区,IF:16.7

256. Zhang W, Liu W, Long L, He S, Wang Z, Liu Y, Yang L, Chen N, Hu C, Wang Y. (2023). Responsive multifunctional hydrogels emulating the chronic wounds healing cascade for skin repair. Journal of Controlled Release. 354, 821-834. (一区,IF:11.5)

255. He S, Zhang Z, Luo R, Jiang Q, Yang L, Wang Y. (2023). Advances in injectable hydrogel strategies for heart failure treatment. Advanced Healthcare Materials. 12(19), 2300029. (一区,IF:11.1)

254. Li K, Peng J, Liu Y, Zhang F, Wu D, Luo R, Du Z, Yang Y, Liu G, Wang Y. (2023). Surface Engineering of Central Venous Catheters via Combination of Antibacterial Endothelium-Mimicking Function and Fibrinolytic Activity for Combating Blood Stream Infection and Thrombosis. Advanced Healthcare Materials. 12(23), 2300120.(一区,IF:11.1)

253. Yan H, Qin Y, Li Y, An Y, Wu H, Chen C, Yang L, Zhang F, Luo R, Jiang Q, Wang Y. (2023). Anti-fouling plus: Engineered stent coating with inflammation-regulation capability enables enhanced tissue healing. Composites Part B: Engineering. 267, 111055. (一区,IF:11.3

252. Liu Y, Zhang W, Hu C, Zheng C, Zhang F, Li Z, Wang Y. (2023). A composite hydrogel improves the survival and differentiation of human iPSC-derived neural stem cells after ischemic stroke.Composites Part B, Engineering. 259, 110711. (一区,IF:11.3

251. Zheng C, Huang X, Ding K, Kuang K, Yang L, Wang Y, Zhang X. (2023). Double bond crosslinked and phosphocholinated biological heart valve with robustantithrombogenicty, durability and anticalcification property. Composites Part B, Engineering. 250, 110448.(一区,IF:11.3

250. Wang Y, Zheng C, Wu Y, Zhang B, Hu C, Guo C, Kong Q, Wang Y. (2023). An Injectable and Self-strengthening Nanogel Encapsuled Hydrogel Gene Delivery System Promotes Degenerative Nucleus Pulposus Repair. Composites Part B, Engineering. 250, 110469.(一区,IF:11.3

249. Yu T, Pu H, Chen X, Kong K, Chen C, Li G, Jiang Q, Wang Y. (2023). A versatile modification strategy for functional non-glutaraldehyde cross-linked bioprosthetic heart valves with enhanced anticoagulant, anticalcification and endothelialization properties. Acta Biomaterialia. 160, 45-58.(一区,IF:10.6

248. Yu T, Zheng C, Chen X, Pu H, Li G, Jiang Q, Wang Y, Guo Y. (2023). A universal strategy for the construction of polymer brush hybrid non-glutaraldehyde heart valves with robust anti-biological contamination performance and improved endothelialization potential. Acta Biomaterialia. 160, 87-97(一区,IF:10.6

247. Fu D, Yang F, Zhang J, Xiang Z, Wang, Y. (2023). Near-Infrared Rechargeable Persistent Luminescence Nanoparticles for Biomedical Implants In Vivo Noninvasive Bioimaging. ACS Applied Materials & Interfaces. 15(46),  53310-53317.(一区,IF:10.4

246. Xiang Z, Zhang J, Zhou C, Zhang B, Chen N, Li M, Fu D, Wang Y. (2023). Near-Infrared Remotely Controllable Shape Memory Biodegradable Occluder Based on Poly(l-lactide-co-ε-caprolactone)/Gold Nanorod Composite. ACS Applied Materials & Interfaces. 15(36),  42341-42353.(一区,IF:10.4

245. Huang H, Trentle M, Liu Z, Xiang K, Higgins W, Wang Y, Xue B, Yang S. (2023). Polymer Complex Fiber: Property, Functionality, and Applications. ACS Applied Materials & Interfaces. 15(6), 7639-7662.(一区,IF:10.4 

244. Long L, Ji D, Hu C, Yang L, Tang S, Wang Y. (2023). Microneedles for in situ tissue regeneration. Materials Today Bio. 19, 100579.(一区,IF:10.7

243. Sheng F, Zhang B, Cheng R, Wei C, Shen S, Ning C, Yang J, Wang Y, Wang Z, Dong K. (2023). Wearable energy harvesting-storage hybrid textiles as on-body selfcharging power systems. Nano Research Energy.  2(4), e9120079. (一区,IF: 19.1)

242. Hu Q, Zhang F, Wei Y, Liu J, Nie Y, Xie J, Yang L, Luo R, Shen B, Wang Y. (2023). Drug Embedded Nano-vesicle Assembled from Peptide-Decorated Hyaluronic acid for Rheumatoid Arthritis Synergistic Therapy. Biomacromolecules. 24(8), 3532-3544. (一区,IF: 7.0)

241. Chen Y, Zhang Y, Wang Q, Dan N, Li Y, Li Z, Dan W, Wang Y. (2023). Converting Acellular Dermal Matrix into On-Demand Versatile Skin Scaffolds by a Balanceable Crosslinking Approach for Integrated Infected Wounds Therapy. Biomacromolecules. 24(5), 2342-2355. (一区,IF: 7.0

240. Chen Y, Xu W, Zheng X, Huang X, Dan N, Wang M, Li Y, Li Z, Dan W, Wang Y. (2023). Two-Layered Biomimetic Flexible Self-Powered Electrical Stimulator for Promoting Wound Healing. Biomacromolecules. 24(3),1483-96.(一区,IF: 7.0

239. Liang X, Yang L, Lei Y, Zhang S, Chen L, Hu C, Wang Y. (2023). Biomimetic-modified bioprosthetic heart valves with Cysteine-Alanine-Glycine peptide for anti-thrombotic, endothelialization and anti-calcification. International Journal of Biological Macromolecules. 250,126244. (一区,IF: 8.2)

238. Zhang Y, Zhang C, Li Y, Zhou L, Dan N, Min J, Chen Y, Wang Y. (2023). Evolution of biomimetic ECM scaffolds from decellularized tissue matrix for tissue engineering: A comprehensive review. International Journal of Biological Macromolecules. 246, 125672 (一区,IF: 8.2)

237. Wang C, Zhang B, Yu S, Zhang H, Zhou W, Luo R, Wang Y, Bian W, Mao, G. (2023). Incorporation of Mg-phenolic networks as a protective coating for magnesium alloy to enhance corrosion resistance and osteogenesis in vivo. Journal of Magnesium and Alloys11(11), 4247-4262. (一区IF:11.8

236. Xiao X, Li L, Deng H, Zhong Y, Deng W, Xu Y, Chen Z, Zhang J, Hu X, Wang Y. (2023). Biomass-derived 2D carbon materials: Structure, Fabrication, and Application in Electrochemical Sensors. Journal of Materials Chemistry B. 11(45), 10793-10821.(二区,IF: 7.6

235. Wu H, Huang K, Hu M, Chen N, Qin Y, Wang J, Luo R, Yang L, Wang Y. (2023). Postfunctionalization of biological valve leaflets with a polyphenol network and anticoagulant recombinant humanized type III collagen for improved anticoagulation and endothelialization. Journal of Materials Chemistry B. 11(38), 9260-9275.(二区,IF: 7.6

234. Chen X, Yu T, Kong K, Xu H, Zhao Z, Li G, Fan H, Wang Y. (2023). A chlorogenic acid functional strategy of anti-inflammation, anti-coagulation and promoted endothelial proliferation for bioprosthetic artificial heart valves. Journal of Materials Chemistry B.  11, 2663-2673.(二区,IF: 7.6

233. Xu Y, Chen S, Zhang Y, Wu C, Li L, Hu X, Zhang J, Wang Y. (2023). Antibacterial black phosphorus nanosheets for biomedical applications. Journal of Materials Chemistry B. 11(30), 7069-7093.(二区,IF: 7.6

232. Li Y, Zhang H, Jiang J, Zhao L, Wang Y. (2023). SiO2@Au nanoshells-Assisted Laser Desorption/Ionization Mass Spectrometry for Coronary Heart Disease Diagnosis. Journal of Materials Chemistry B. 11, 2862-2871(二区,IF: 7.6

231. Li L, Zhou Y, Xiao X, Chen Z, Zhou Z, Deng W, Xu Y, Li G, Zhang J, Hu X, Wang Y. (2023). 3D Biomass-derived Carbon Materials for Electrochemical Sensors. Advanced Materials Technologies. 8(21), 2300666. (二区,IF: 8.8)

230. Chen N, Li M, Wu H, Qin Y, Wang J, Xu K, Luo R, Yang L, Wang Y, Zhang X (2023). An extracellular matrix-mimeticcoating with dual bionics for cardiovascularstents. Regenerative Biomaterials. Volume 10, rbad055 (一区,IF: 5.8)

229. Zhang T, Dou Y, Luo R, Yang L, Zhang W, Ma K, Wang Y, Zhang X. (2023). A review over the development of interventional mitral valve repair devices of artificial chordal implantation for treating mitral regurgitation.  Frontiers in Bioengineering and Biotechnology. 11, 1173413. (二区,IF:6.1) 

228. Lang W, Huang H, Yang L, Luo R, Wang Y, Xue B, Yang S. (2023). Polymer complex multilayers for drug delivery and medical devices. ACS Applied Bio Materials. 6(9), 3555-3565. (IF: 4.7)

227. Yu G, Zhang Y, Wang Q, Dan N, Chen Y, Li Z, Dan W, Wang Y. (2023). Wearable and Flexible Hydrogels for Strain Sensing and Wound Electrical Stimulation. Industrial & Engineering Chemistry Research.  62(13), 5468-5481. (三区,IF:4.3

226. Zhao J, Song G, Zhao Q, Feng H, Zhao H, Liu Q, Wang Y. (2023). Development of Three-Dimensionally Printed Vascular Stents of Bioresorbable Poly(L-lactide-co-caprolactone). Journal of Biomedical Materials Research Part B: Applied Biomaterials111(3), 656–664.(三区,IF:3.4

225. Guan S, Zhu S, Zheng Y, Wang Y, Zhang X (2023). Research Progress and Future Development of Nonferrous Biomedical Materials. Chinese Journal of Engineering Science. 25(1), 104-122.

224. Wang B, Wang S, Gao C, Lim S, Wang R, Zhu C, Liu Y, Meng X, Onuma Y, Serruys P, Wang Y, Gao R, Lee R, Tao L. (2023). First-in-Man Use of Novel Catheter-Based Intramyocardial Injection Platform X-DROP for Endocardial Alginate-Hydrogel Injection in the Treatment of Heart Failure. Journal of the American College of Cardiology. 82(17_Supplement), B162.  (一区,IF:27.2)

223. 王云兵、郭高阳, 可降解高分子材料在心血管治疗植介入器械中的应用。同济大学学报(自然科学版), 2023, Vol. 51, No. 11, 1649-1656

222. 何晓棠、但哗、陈一宁、王云兵、胡晓兵、李正军、但为华,胶原基生物材料制备与应用研究进展,材料导报,2023. 37(2),21030226.

2022年:

221. Wang Y, Li G, Yang L, Luo R, Guo G. (2022). Development of innovative biomaterials and devices for the treatment of cardiovascular diseases. Advanced Materials. 34(46), 2201971. (中科院一区IF:32.1) 

220. Zhou Z, Luo R, Hu C, Chen L, Chen C, Maitz M, Li L, Yang L, Deng D, An Y, Wu H, Yang Y, Dai Y, Xin J, Wang Y. (2022). Dressing blood-contacting devices by platelet membrane enables large-scale multifunctional biointerfacing. Matter. 5(1),1-18.(一区, IF:20.0

219. Wang Y, Wu H, Zhou Z, Maitz M, Liu K, Zhang B, Yang L, Luo R, Wang Y. (2022). A Thrombin-triggered self-regulating anticoagulant strategy combined with anti-inflammatory capacity for blood-contacting implants. Science Advances. 8 (9), eabm3378.(一区,IF:15.0

218. Zhang H, Zhao L, Jiang J, Zheng J, Yang L, Zhou J, Liu T, Xu J, Lou W, Yang W, Tan J, Liu W, Yu Y, Ji M, Xu Y, Lu Y, Li X, Liu Z, Tian R, Hu C, Zhang S, Hu Q, Deng Y, Ying H, Zhong S, Zhang X, Wang Y, Wang H, Bai J, Li X, Duan X. (2022). Multiplexed Nanomaterial-Assisted Laser Desorption/Ionization for Pan-cancer Diagnosis and ClassificationNature Communications. 13(1), 1-11. (一区,IF:17.7) 

217. Zhang B, Qin Y, Yang L, Wu Y, Chen N, Li M, Li Y, Wan H, Fu D, Luo R, Yuan L, Wang Y. (2022). A Polyphenol-Network-Mediated Coating Modulates Inflammation and Vascular Healing on Vascular StentsACS Nano. 16 (4), 6585–6597. (一区,IF:18.0)

216. Guo G, Hu J, Wang F, Fu D, Luo R, Zhang F, Hu C, Chen J, Pan X, Yang L, Wang Y, Zhang X. (2022). A fully degradable transcatheter ventricular septal defect occluder: Towards rapid occlusion and post-regeneration absorption. Biomaterials. 291, 121909.  (一区, IF:15.3)  

215. Hu C, Liu W, Long L, Wang Z, Zhang W, He S, Lu L, Fan H, Yang Y, Wang Y. (2022).  Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis properties. Biomterials. 290, 121849. (一区, IF:15.3)  

214. Yang F, Guo G, Wang Y. (2022). Inflammation-triggered dual release of nitroxide radical and growth factor from heparin mimicking hydrogel-tissue composite as cardiovascular implants for anti-coagulation, endothelialization, anti-inflammation, and anti-calcification,  Biomaterials. 289, 121761. (一区, IF:15.3)  

213. Xu H, She P, Ma B, Zhao Z, Li G, Wang Y. (2022). ROS Responsive Nanoparticles Loaded with Lipid-Specific AIEgen for Atherosclerosis-Targeted Diagnosis and Bifunctional Therapy.  Biomaterials.   288, 121734. (一区, IF:15.3)  

212. Zhang B, Qin Y, Wang Y. (2022). A Nitric Oxide-eluting and REDV Peptide-conjugated Coating Promotes Vascular Healing. Biomaterials.  284121478.  (一区,IF:15.3) 

211. Zhang B, Qin Y, Yang L, Wan H, Yuan L, Wang Y. (2022). An Organic Selenium and VEGF-Conjugated Bioinspired Coating Promotes Vascular Healing. Biomaterials. 287, 121654.  (一区, IF:15.3 

210. Wu H, He Q, Li L, L L, Zhou Z, Chen N, Yang M, Luo Q, Zhang B, Luo R, Yang L, Wang Y. (2022). A facile and versatile superhydrophilic coating on biodegradable PLA stent with stepwise assembly of metal/phenolic networks for mimicking endothelium function. Chemical Engineering Journal. 427, 130932.(一区,IF:16.7

209. Yang L, Wu H, Liu Y, Xia Q, Luo R, Yang Y, Chen N, Yang M, Liu G, Wang Y. (2022). A Robust Mussel-inspired zwitterionic coating on biodegradable poly(L-lactide) stent with enhanced anticoagulant, anti-inflammatory and anti-hyperplasia properties. Chemical Engineering Journal. 427, 130910.(一区,IF:16.7

208. Liu Y, Zhang F, Long L, Li J, Liu Z, Hu C, Chen X, Zan X, Xu J, Wang Y. (2022). Dual-function Hydrogels with Sequential Release of GSK3β Inhibitor and VEGF Inhibit Inflammation and Promote Angiogenesis after Stroke.  Chemical Engineering Journal. 433,133671. (一区,IF:16.7)

207. Zhang F, Hu QWei Y, Meng W, Wang R, Liu J, Nie Y, Luo R, Wang Y, Shen B. (2022). Surface modification of titanium implants by pH-Responsive coating designed for Self-Adaptive antibacterial and promoted osseointegrationChemical Engineering Journal. 435, 134802. (一区,IF:16.7

206. Wu Y, Wang Y, Long L, Hu C, Kong Q, Wang Y. (2022). A spatiotemporal release platform based on pH/ROS stimuli-responsive hydrogel in wound repairing. Journal of Controlled Release. 341, 147–165.(一区,IF:11.5)

205. Wu C, Long L, Zhang Y, Xu Y, Lu Y, Yang Z, Guo Y, Zhang J, Hu X, Wang Y. (2022). Injectable conductive and angiogenic hydrogels for chronic diabetic wound treatment. Journal of Controlled Release. 344,249-260.(一区,IF:11.5)

204. Zheng C, Ding K, Huang X, Li M, Wu B, Lei Y, Wang Y. (2022). Nonglutaraldehyde crosslinked bioprosthetic heart valves based on 2-isocyanatoethyl methacrylate crosslinked porcine pericardium with improved properties of stability, cytocompatibility and anti-calcification. Composites Part B, Engineering. 230, 109504.(一区,IF:11.3

203. Zhang S, Zheng C, Li M, Ding K, Huang X, Liang X, Lei Y, Jiang Q, Wang Y. (2022). Sodium Lignosulfonate Cross-linked Bioprosthetic Heart Valve Materials for Enhanced Cytocompatibility, Improved Hemocompatibility, and Reduced Calcification. Composites Part B, Engineering. 234,109669.(一区,IF:11.3

202. Ge Y, Guo G, Liu K, Yang F, Yang L, Wang Y, Zhang X. (2022). A strategy of functional crosslinking acellular matrix in blood-contacting implantable devices with recombinant humanized collagen type III (rhCOLIII). Composites Part B, Engineering. 234,109667.(一区,IF:11.3

201. Li L, Liu L, Li L, Guo F, Ma L, Fu P, Wang Y (2022). Chitosan Coated Bacteria Responsive Metal-polyphenol Coating as Efficient Platform for Wound Healing. Composites Part B, Engineering. 234,109665.(一区,IF:11.3

200. Wang Y, Deng M, Wu Y, Hu C, Zhang B, Guo C, Song H, Kong Q, Wang Y. (2022). Sustained gene delivery from inflammation-responsive anti-inflammatory hydrogels promotes extracellular matrix metabolism balance in degenerative nucleus pulposus. Composites Part B, Engineering. 236,109806.(一区,IF:11.3

199. Zheng C, Ding K, Huang X, Yang L, Wang Y. (2022). A bioprosthetic heart valve prepared by copolymerization of 2-isocyanatoethyl methacrylate modified pericardium and functional monomer. Composites Part B, Engineering. 238, 109922(一区,IF:11.3

198. Ding K, Zheng C, Huang X, Yang L, Lei Y, Wang Y. (2022). A bioprosthetic heart valve material prepared by copolymerization of 2-Amino-4-pentanoic acid modified pericardium and N, N-Dimethylacrylamide. Composites Part B, Engineering. 243, 110120.(一区,IF:11.3

197. Huang X, Zheng C, Ding K, Zhang S, Lei Y, Wei Q, Yang L, Wang Y. (2022). Dual-crosslinked Bioprosthetic Heart Valves Prepared by Glutaraldehyde Crosslinked Pericardium and Poly-2-hydroxyethyl Methacrylate Exhibited Improved Antithrombogenicity and Anticalcification Properties. Acta Biomaterialia. 154, 244-258.(一区,IF:10.6

196. Ding K, Zheng C, Huang X, Zhang S, Li M, Lei Y, Wang Y. (2022). A PEGylation method of bioprosthetic heart valves based on glutaraldehyde and 2-amino-4-pentenoic acid co-crosslinking with improved antithrombogenicity and cytocompatibility properties.  Acta Biomaterialia. 144,279-291(一区,IF:10.6

195. Chen L, Zhou Z, Hua C, Maitz M, Yang L, Luo R, Wang Y (2022). Platelet Membrane-Coated Nanocarriers Targeting Plaques to Deliver anti-CD47 Antibody for Atherosclerotic Therapy. Research. 16, 1-12. (区,IF:11.0) 

194. Shen L, Liang Z, Chen Z, Wu C, Hu X, Zhang J, Jiang Q, Wang Y. (2022). Reusable electrochemical non-enzymatic glucose sensors based on Au-inlaid nanocages. Nano Research. 15, 6490–6499. (区,IF:10.3)  

193. Long L, Hu C, Liu W, Wu C, Lu L, Yang L, Wang Y. (2022). Injectable multifunctional hyaluronic acid/methylcellulose hydrogels for chronic wounds repairing. Carbohydrate Polymers. 289, 119456. (一区,IF:10.7)

192. Kong Q, Li G, Zhang F, Yu T, Chen X, Jiang Q, Wang Y. (2022). N-arylimidazoliums as highly selective biomimetic antimicrobial agents. Journal of Medicinal Chemistry.  65(16), 11309-11321. (一区IF: 8.0

191. Wei Y, Liu J, Liu G, Gao S, Wu D, Yang L, Luo R, Zhang F, Wang Y. (2022). Hemocompatibility Multi-in-One Hydrogel Coating with ROS-Triggered Inflammation Suppression and Anti-Infection Properties for Blood-Contacting Device. Biomacromolecules. 23(10), 4357-4369.(一区,IF:7.0

190. Li L, Yang L, Liu K, Wang Y, Zhang B, Shen J, Liu P, Luo R, Wang, Y. (2022). Nanoparticles-stacked Superhydrophilic Coating Supported Synergistic Antimicrobial Ability for Enhanced Wound Healing. Materials Science & Engineering C. 132,112535.(二区,IF: 8.4

189. Long L, Hu C, Liu W, Wu C, Lu L, Yang L, Wang Y. (2022). Microfibrillated cellulose-enhanced carboxymethyl chitosan/oxidized starch sponge for chronic diabetic wound repair. Materials Science & Engineering C.135, 112669. (二区,IF:8.4

188. Long L, Liu W, Li L, Hu C, He S, Lu L, Wang J, Yang L, Wang Y. (2022). Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via anti-inflammation and enhanced cell proliferation and angiogenesis. Nanoscale. 14, 1285-1295. (二区,IF:8.3

187. Long L, Liu W, Hu C, Yang L, Wang Y. (2022). Construction of multifunctional wound dressings with their application in chronic wound treatment. Biomaterials Science. 10(15),  4058-4076.(二区,IF:7.6

186. Liang X, Lei Y, Ding K, Huang X, Zheng C, Wang Y. (2022). Poly (2-methoxyethyl acrylate) coated bioprosthetic heart valves by copolymerization with enhanced anticoagulant, anti-inflammatory, and anti-calcification properties.  Journal of Materials Chemistry B. 10(48), 10054 - 10064.(二区,IF:7.6

185. Zheng C, Kuang D, Ding K, Huang X, Fan H, Yang L, Wang Y, Zhang X. (2022). A functionalized biological heart valve by double bond crosslinking with enhanced biocompatibility and antithrombogenicity.  Journal of Materials Chemistry B. 10(48), 10001 - 10017.(二区,IF:7.6

184. Liang X, Zheng C, Ding K, Huang X, Zhang S, Lei Y, Yu K, Wang Y. (2022). Arginine-grafted porcine pericardium by copolymerization to improve cytocompatibility, hemocompatibility and anti-calcification properties of bioprosthetic heart valve materials. Journal of Materials Chemistry B.  10(29), 5571-5581. (二区,IF:7.6

183. Xu Q, Chen Z, Zhang Y, Hu X, Chen F, Zhang L, Zhong N, Zhang J, Wang Y. (2022). Mussel-inspired bioactive 3D-printable poly(styrene-butadiene-styrene) and the assessment of its potential as cranioplasty implants. Journal of Materials Chemistry B. 10(19), 3747-3758(二区,IF:7.6

182. Li M, Liu K, Liu Y, Chen N, Wang Y, Zhang F, Luo Q, Yang Y, Luo R, Wang Y.(2022). A universal anti-thrombotic and antibacterial coating: A chemical approach directed by Fenton reaction and silane coupling. Applied Surface Science. 600 (30), 154143. (二区,IF:7.4

181. Yu H, Hou Z, Chen N, Luo R, Yang L, Miao M, Ma X, Zhou L, He F, Shen Y, Liu X, Wang Y. (2022). Yes-associated Protein Contributes to Magnesium Alloy-derived Inflammation in Endothelial Cells. Regenerative Biomaterials. 9, rbac002. (一区,IF:5.8)  

180. Shen X, Zhang H, Li X, Li P, Zhao Y, Wang Y, Wang J. (2022). A hydrophobic layer prepared by cyclic grafting of polydimethylsiloxane (PDMS) on magnesium: improved corrosion resistance and biocompatibility. Regeneretive Biomaterials. 9, rbac068.  (一区,IF:5.8)  

179. Zhang H, Shen X, Fei Z, Fan X, Ma L, Wang H, Tian C, Zhang B, Luo R, Wang Y, Huang S. (2022). Ag-Incorporated Polydopamine/Tannic Acid Coating on Titanium With Enhanced Cytocompatible and Antibacterial Properties.  Frontiers in Bioengineering and Biotechnology. 10, 877738(二区,IF:6.1)   

178. Yu H, Hou Z, Xiang M, Yang Y, Ma J, Yang Y, Ma X, Zhou L, He F, Miao M, Liu X, Wang Y. (2022). Arsenic Trioxide Activates Yes-associated Protein by Lysophosphatidic Acid Metabolism to Selectively Induce Apoptosis of Vascular Smooth Muscle Cells. BBA -Molecular Cell Research. 1869(4), 119211.二区,IF:5.2) 

177. Huang X, Zheng C, Ding K, Li M, Zhang S, Wu B, Wei Q, Lei Y, Wang Y. (2022). Hyaluronic Acid-Grafted Bioprosthetic Heart Valves Achieved by Copolymerization Exhibited Improved Anticalcification and Antithrombogenicity. ACS Biomaterials Science & Engineering. 8(8), 3399-3410.二区,IF:5.4) 

176. Yang F, Xu L, Jin L, Guo G, Wang Y. (2022). Visible light–induced cross-linking of porcine pericardium for the improvement of endothelialization, anti-tearing, and anticalcification properties. Journal of Biomedical Materials Research - Part A. 110(1), 31–42. (二区,IF:4.8)

175. Huang X, Zheng C, Ding K, Zhang S, Wei Q, Yang L, Wang Y. (2022). Poly(2-Methacryloyloxyethyl Phosphorylcholine) Grafted Bioprosthetic Heart Valve Exhibited Improved Antithrombogenicity and Anticalcification Properties. ACS Applied Polymer Materials. 4(11), 8418-8428.(三区,IF:4.8

174. Yang N, Chen Y, Dan N, Zheng X, Feng R, Yu G, He X, Dan W, Wang Y. (2022). Flexible nano-piezoelectric membranes with spontaneous electric field generation for bacteria elimination and wound healing. Journal of Materials Science. 57(41), 19532-19552.(三区,IF:4.2

173. Li M, Zheng C, Zhang S, Wu B, Ding K, Huang X, Lei Y, Wang Y. (2022). A hydrophobic antifouling surface coating on bioprosthetic heart valves for enhanced antithrombogenicity. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 110(5), 1082-1092.  (三区,IF:3.4

172. Chen M, Wang Q, Wang Y, Fan Y, Zhang X. (2022). Biomaterials-assisted exosomes therapy in osteoarthritis. Biomedical Materials.  17(2), 022001.三区,IF:3.7

171. Wan H, Sun C, Zhang J, Hu X, Wang Y (2022). Recent Advances in Implantable Hydrogels for Treating Heart Failure. Journal of Applied Polymer Science. 139(46), e53156. (三区,IF: 3.1) 

170. Zuo S, Lan X, Wang Y, Li S, Tang Z, Wang Y. (2022). Preparation and characterization of photopolymerized poly(l-lactide--ε-caprolactone--vinyl-2-pyrrolidone) network as anti-biofouling materials. RSC Advances, 12(14), 8708-8718.三区,IF:4.1

169. Li M, Zheng C, Wu B, Ding K, Zhang S, Huang X, Lei Y, Wang Y. (2022). Glycidyl methacrylate-crosslinked fish swim bladder as a novel cardiovascular biomaterial with improved antithrombotic and anticalcification properties. Journal of Biomaterials Applications. 36(7), 1188-1200(三区,IF:2.7

168. Zhang Z, Xiong Y, Hu J, Guo X, Xu X, Juan Chen J, Wang Y, Chen Y. (2022). A Finite Element Investigation on Material and Design Parameters of Ventricular Septal Defect Occluder Devices. Journal of Functional Biomaterials. 13(4), 182. (IF: 4.9)

167. Chen Y, Liu X, Zheng X, Huang X, Dan W, Li Z, Dan N, Wang Y. (2022). Advances on the modifcation and biomedical applications of acellular dermal matrices. Journal of Leather Science and Engineering4(1), 1-19.

166. Chen X, Yu T, Kong Q, Kuang D, Xu H, Zhao Z, Yang L, Li G, Fan H, Wang Y. (2022). Functional non-glutaraldehyde treated porcine pericardium for anti-coagulation, anti-calcifcation, and endothelial proliferation bioprosthetic heart valves. Journal of Leather Science and Engineering. 4(1), 1-13. 

165. Hu C, Yang L, Wang Y. (2022). Recent advances in smart-responsive hydrogels for tissue repairing. MedComm - Biomaterials and Applications. 1(2), e23.

164. Wu Y, Hu C, Wang Y. (2022). Recent advances in the application of biomimetic nanomedicines in disease treatment. Biomedical Engineering Communications. 1(1), 4.

163.  刘巍、匡大军、杨剑、杨立、刘兆刚、许莎莎、雷洋、王云兵,国产经导管人工主动脉自膨胀瓣膜植入术后2年组织学分析,中国介入心脏病学杂志,2022,30(6): 462-466.

2021年:

162. Wang Y, Ma B, Liu K, Luo R, Wang Y. (2021). A multi-in-one strategy with glucose-triggered long-term antithrombogenicity and sequentially enhanced endothelialization for biological valve leaflets. Biomaterials. 275, 120981. (一区,IF:15.3

161.Yang L, Wu H, Lu L, He Q, Luo R, Wang Y, Zhang X. (2021). A Tailored Extracellular Matrix (ECM) - Mimetic Coating for Cardiovascular Stents by Stepwise Assembly of Hyaluronic Acid and Recombinant Human Type III Collagen. Biomaterials.  276, 121055.(一区,IF:15.3

160. Zhang B, Yao R, Hou Z, Yu H, Luo R, Wang Y. (2021). Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release. Biomaterials. 269, 120418.(一区,IF:15.3

159. Wang Y. (2021). Research and Progress of Implantable Cardiovascular Materials and Devices. Engineering. 7(12), 1707-1709.(一区,IF:12.8

158. Liu K, Zhang F, Wang Y, Chen C, Li M, Wei Y, Yang L, Luo R, Wang Y. (2021) Chemical bonding of biological valve leaflets with an aminated zwitterionic copolymer for long-term anticoagulation and improved anti-calcification. Chemical Engineering Journal. 426, 131803.(一区,IF:16.7

157. Zhang B, Yao R, Hou Z, Yu H, Luo R, Wang Y. (2021). Poly (dimethyl diallyl ammonium chloride) incorporated multilayer coating on biodegradable AZ31 magnesium alloy with enhanced resistance to chloride corrosion and promoted endothelialization. Chemical Engineering Journal, 421, 127724.(一区,IF:16.7

156 Yu T, Yang W, Zhuang W, Tian Y, Kong Q, Chen X, Li G, Wang Y. (2021). Nonglutaraldehyde treated porcine pericardium with good biocompatibility, reduced calcification and improved Anti-coagulation for bioprosthetic heart valve applications. Chemical Engineering Journal. 414, 128900(一区,IF:16.7

155. Hu C, Long L, Cao J, Zhang S, Wang Y. (2021). Dual-crosslinked mussel-inspired smart hydrogels with enhanced antibacterial and angiogenic properties for chronic infected diabetic wound treatment via pH-responsive quick cargo release. Chemical Engineering Journal. 411, 128564.高被引文章,一区,IF:16.7

154. Yang F, Xu L, Kuang D, Ge Y, Guo G, Wang Y. (2021). Polyzwitterion-crosslinked hybrid tissue with antithrombogenicity, endothelialization, anticalcification properties. Chemical Engineering Journal. 410, 128244.(一区,IF:16.7

153. Liu Y, Long, L, Zhang F, Hu X, Zhang J, Hu C, Wang Y, Xu J. (2021). Microneedle-Mediated Vascular Endothelial Growth Factor Delivery Promotes Angiogenesis and Functional Recovery After Stroke. Journal of Controlled Release. 338, 610–622.(一区,IF:11.5

152. Wu C, Shen L, Lu Y, Hu C, Liang Z, Long L, Ning N, Chen J, Guo Y, Yang Z, Hu X, Zhang J, Wang Y. (2021). Intrinsic Antibacterial and Conductive Hydrogels Based on the Distinct Bactericidal Effect of Polyaniline for Infected Chronic Wound Healing. ACS Applied Materials & Interfaces. 13(44), 52308-52320.(一区,IF:10.4

151. Liu K, Zhang F, Wei Y, Hu Q, Luo Q, Chen C, Wang J, Yang L, Luo R, Wang, Y. (2021). Dressing Blood-Contacting Materials by a Stable Hydrogel Coating with Embedded Antimicrobial Peptides for Robust Antibacterial and Antithrombus Properties. ACS Applied Materials & Interfaces. 33(13), 38947–38958.(一区,IF:10.4

150.  Ma B, Xu H, Wang Y, Yang L, Zhuang W, Li G, and Wang Y. (2021). Biomimetic-Coated Nanoplatform with Lipid-Specific Imaging and ROS Responsiveness for Atherosclerosis-Targeted Theranostics. ACS Applied Materials & Interfaces.  13(30), 35410-35421.(一区,IF:10.4

149. Wang Y, Wu Y, Long L, Yang L, Fu D, Hu C, Kong Q, Wang Y. (2021). Inflammation-responsive drug-loaded hydrogels with sequential hemostasis, antibacterial, and anti-Inflammatory behavior for chronically infected diabetic wound treatment. ACS Applied Materials & Interfaces. 13(28), 33584-33599.(一区,IF:10.4

148. Guo G, Jin L, Wu B, He H, Yang F, Xu L, Lei Y, Wang Y. (2021). A method for simultaneously crosslinking and functionalizing extracellular matrix-based biomaterials as bioprosthetic heart valves with enhanced endothelialization and reduced inflammation. Acta Biomaterialia. 119, 89-100.(一区,IF:10.6

147. Chen J, Dai S, Liu L, Liao Y, Cui J, Zhao A, Huang N, Wang Y. (2021). Photo-functionalized TiO2 nanotubes decorated with multifunctional Ag nanoparticles for enhanced vascular biocompatibility. Bioactive Materials. 6(1), 45-54.(一区,IF:16.9

146. Zhu G, Zhang T, Chen M, Yao K, Huang X, Zhang B, Li Y, Liu J, Wang Y, Zhao Z. (2021). Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds. Bioactive Materials. 6(11), 4110-4140.高被引文章,一区,IF:16.9

145. Wang J, Qian H, Chen S, Huang W, Hao H, Ren K, Wang Y, Ji J. (2021). miR-22 eluting cardiovascular stent based on a self-healable spongy coating inhibits in-stent restenosis. Bioactive Materials. 6(12), 4686-4696.(一区,IF:16.9

144. Hu M, Jia F, Huang W, Li X, Hu D, Wang J, Ren K, Fu G, Wang Y, Ji J. (2021). Substrate stiffness differentially impacts autophagy of endothelial cells and smooth muscle cell. Bioactive Materials. 6(5), 1413-1422.(一区,IF:16.9

143. Zhao Y, Zang G, Yin T, Ma X, Zhou L, Wu L, Daniel R, Wang Y, Qiu J, Wang G. (2021). A novel mechanism of inhibiting in-stent restenosis with arsenic trioxide drug-eluting stent: Enhancing contractile phenotype of vascular smooth muscle cells via YAP pathway. Bioactive Materials. 6(2), 375-385.(一区,IF:16.9

142. Wu B, Zheng C, Ding K, Huang X, Li M, Zhang S, Lei Y, Guo Y, Wang Y. (2021). Cross-Linking Porcine Pericardium by 3,4-Dihydroxybenzaldehyde: A Novel Method to Improve the Biocompatibility of Bioprosthetic Valve. Biomacromolecules. 22(2), 823–836. (一区,IF:7.0

141. Xiang Y, Jin R, Zhang Y, Li K, Liu G, Song X, Wang Y, Nie Y. (2021). Foldable Glistening-Free Acrylic Intraocular Lens Biomaterials with Dual-Side Heterogeneous Surface Modification for Postoperative Endophthalmitis and Posterior Capsule Opacification Prophylaxis. Biomacromolecules. 22(8), 3510–3521.(一区,IF:7.0

140. Lei Y, Lan X, He Z, Yin A, Jin W, Hu Q, Wang Y. (2021). Multifarious anti-biofouling bioprosthetic heart valve materials with the formation of interpenetrating polymer network structures. Materials and Design, 206, 109803.(一区,IF:9.4

139. Li S, Zhuang W, Chen J, Li L, Li G, Li J, Liao Y, Chen M, Wang Y. (2021). A lipid droplets specific probe for imaging of atherosclerosis and fibrocalcific bicuspid aortic valves. Sensors and Actuators B: Chemical. 346, 130458.(一区,IF: 9.2)

138. Li L, Chen C, Zhang C, Luo R, Lan X, Guo F, Ma L, Fu P, Wang Y. (2021). A honokiol-mediated robust coating for blood-contacting devices with anti-inflam9atory, antibacterial and antithrombotic properties. Journal of Materials Chemistry B. 9(47), 9770–9783.(二区,IF:7.6

137. Hu C, Liu W, Long L, Wang Z, Yuan Y, Zhang W, He S, Wang J, Yang L, Lu L, Wang Y. (2021). Microenvironment-responsive multifunctional hydrogels with spatiotemporal sequential release of tailored recombinant human collagen type III for the rapid repair of infected chronic diabetic wounds. Journal of Materials Chemistry B. 9(47), 9684–9699.(二区,IF:7.6

136. Wu Y,  Lu Y,   Wu C,  Chen J,  Ning N,   Yang Z,  Guo Y,  Zhang J,  Hu X, Wang Y (2021). Conductive dual hydrogen bonding hydrogels for the electrical stimulation of infected chronic wounds. Journal of Materials Chemistry B. 9(38), 8138-8146.(二区,IF:7.6

135. Zhuang W, Tan P, Li S, Li C, Zhang J, Ai J, Yang L, Li G, Wei Q, Chen M, Wang Y. (2021). A lipid droplet specific fluorescent probe for image-guided photodynamic therapy under hypoxia. Journal of Materials Chemistry B. 9(46), 9553–9560.(二区,IF:7.6

134. Yu T, Yang W, Zhuang W, Tian Y, Kong Q, Chen X, Li G, Wang Y. (2021). A bioprosthetic heart valve cross-linked by a non-glutaraldehyde reagent with improved biocompatibility, endothelialization, anti-coagulation and anti-calcification properties. Journal of Materials Chemistry B. 9(19), 4031-4038.(二区,IF:7.6
133. Zhang F, Hu C, Yang L, Liu K, Ge Y, Wei Y, Wang J, Luo R, Wang Y. (2021). A conformally adapted all-in-one hydrogel coating: Towards robust hemocompatibility and bactericidal activity. Journal of Materials Chemistry B. 9(11), 2697-2708.
(二区,IF:7.6

132. Zhang T, Guo G, Yang L, Wang Y. (2021). An ultralow dose paclitaxel coated drug balloon with an outer protective sheath for peripheral arterial disease treatment. Journal of Materials Chemistry B. 2021, 9(10), 2428-2435.(二区,IF:7.6

131. Lan X, Lei Y, He Z, Yin A, Li L, Tang Z, Li M, Wang Y. (2021). A transparent hydrophilic anti-biofouling coating for intraocular lens materials prepared by “bridging” of the intermediate adhesive layer. Journal of Materials Chemistry B. 9(17), 3696-3704.(二区,IF:7.6

130. Li S, Zhuang W, Chen J, Li G, Li C, Chen L, Liao Y, Chen M, Wang Y. (2021). Turn-on fluorescent probe for lipid droplet specific imaging of fatty liver and atherosclerosis. Journal of Materials Chemistry B. 9(19), 4050–4055.(二区,IF:7.6

129. Yang F, He H, Xu L, Jin L, Guo G, Wang Y. (2021). Inorganic-polymerization crosslinked tissue-siloxane hybrid as potential biomaterial for bioprosthetic heart valves. Journal of Biomedical Materials Research - Part A. 109(5), 754-765.(二区,IF:4.8

128. Yang L, Xie S, Ding K, Lei Y, Wang Y. (2021). The study of dry biological valve crosslinked with a combination of carbodiimide and polyphenol. Regenerative Biomaterials. 8(1), rbaa049. (一区,IF: 5.8)

127. Hou Z, Xiang M, Chen N, Cai X, Zhang B, Luo R, Yang L, Ma X, Zhou L, He F, Yu H, Wang Y. (2021). The biological responses and mechanisms of endothelial cells to magnesium alloy. Regenerative Biomaterials. 8(3), rbab017. (一区,IF: 5.8)  

126. Chen J, Wang Y, Ren K, Wang Y, Fu G, Ji J. (2021). The influence of substrate stiffness on osteogenesis of vascular smooth muscle cells. Colloids and Surfaces B: Biointerfaces. 197, 111388.(二区,IF:6.0

125. Yu H, He J, Su G, Wang Y, Fang F, Yang W, Gu K, Wang Y, Shen Y, Liu X. (2021). Fluid Shear Stress Activates YAP to Promote Epithelial‐mesenchymal Transition in Hepatocellular Carcinoma. Molecular Oncology. 15(11), 3164–3183. (二区,IF:7.4)

124. Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q. (2021). NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop. Journal of Cellular and Molecular Medicine. 25(13), 5976–5987. (二区,IF:5.3)

123. Liu Y, Zhang F, Lang S, Yang L, Gao S, Wu D, Liu G, Wang Y. (2021). A Uniform and Robust Bioinspired Zwitterion Coating for Use in Blood-Contacting Catheters with Improved Anti-Inflammatory and Antithrombotic Properties. Macromol Biosci. Macromolecular Bioscience, 21(12), 2100341.(三区,IF:5.9

122. Xu L, Yang F, Ge Y, Guo G, Wang Y. (2021). Crosslinking porcine aortic valve by radical polymerization for the preparation of BHVs with improved cytocompatibility, mild immune response, and reduced calcification. Journal of Biomaterials Applications. 35(9), 1218-1232.(三区,IF:2.7

121. Xu H, Zhong J, Zhuang W, Jiang J, Ma B, He H, Li G, Liao Y, Wang, Y. (2021). A bifunctional mitochondrial targeting AIE-active fluorescent probe with high sensitivity to hydrogen peroxide and viscosity for fatty liver diagnosis. New Journal of Chemistry. 45(27), 12138-12144.(三区,IF: 3.9)

120. Wang Y, Lan X, Zuo S, Zou Y, Li S, Tang Z, Wang Y. (2021). Photopolymerized poly(l-lactide-b-N-vinyl-2-pyrrolidone) network resists cell adhesionin situ. RSC Advances. 11(34), 20997-21005.(三区,IF:4.0

119. Xu Q, Hu X, Wang Y. (2021). Alternatives to Conventional Antibiotic Therapy: Potential Therapeutic Strategies of Combating Antimicrobial-Resistance and Biofilm-Related Infections. Molecular Biotechnology. 63(12):1103-1124. (四区,IF:2.9

2020

118. Ma B, Xu H, Zhuang W, Wang Y, Li G, Wang Y. (2020). Reactive oxygen species responsive theranostic nanoplatform for two-photon aggregation-induced emission imaging and therapy of acute and chronic inflammation. ACS Nano. 14(5), 5862-5873.(一区,IF:18.0

117. Li L, Yang L, Liao Y, Yu H, Liang Z, Zhang B, Lan X, Luo R, Wang Y. (2020). Superhydrophilic versus normal polydopamine coating: a superior and robust platform for synergistic antibacterial and antithrombotic properties. Chemical Engineering Journal. 402, 126196.(一区,IF:16.7

116. Ma B, Xu H, Zhuang W, Wang Y, Li G, Wang Y. (2020). ROS responsive nanoplatform with two-photon AIE imaging for atherosclerosis diagnosis and "Two-Pronged" therapy. Small. 16(45), 2003253-e2003253.(一区,IF:15.2

115. Liang Z, Zhang J, Wu C, Hu X, Lu Y, Wang G, Yu F, Zhang X, Wang Y. (2020). Flexible and self-healing electrochemical hydrogel sensor with high efficiency toward glucose monitoring. Biosensors and Bioelectronics. 155,112105.(一区,IF:12.5

114. Hu C, Luo R, Wang Y. (2020). Heart valves cross-linked with erythrocyte membrane drug-loaded nanoparticles as a biomimetic strategy for anti-coagulation, anti-Inflammation, anti-calcification, and endothelialization. ACS Applied Materials & Interfaces. 12(37), 41113-41126.(一区,IF:10.4

113. Zhang J, Wu C, Xu Y, Chen J, Ning N, Yang Z, Guo Y, Hu X, Wang Y. (2020). Highly stretchable and conductive self-healing hydrogels for temperature and strain sensing and chronic wound treatment. ACS Applied Materials & Interfaces. 12(37), 40990-40999.(一区,IF:10.4

112. Yang L, Li L, Wu H, Zhang B, Luo R, Wang Y. (2020). Catechol-mediated and copper-incorporated multilayer coating: An endothelium-mimetic approach for blood-contacting devices. Journal of Controlled Release. 321,59-70.(一区,IF:11.5

111. Wang Y, Ma B, Yin A, Zhang B, Luo R, Pan J, Wang Y. (2020). Polycaprolactone vascular graft with epigallocatechin gallate embedded sandwiched layer-by-layer functionalization for enhanced antithrombogenicity and anti-inflammation. Journal of Controlled Release. 320, 226-238.(一区,IF:11.5

110. Hu C, Zhang F, Long L, Kong Q, Luo R, Wang Y. (2020). Dual-responsive injectable hydrogels encapsulating drug-loaded micelles for on-demand antimicrobial activity and accelerated wound healing. Journal of Controlled Release. 324(10), 204-217.(高被引文章,一区,IF:11.5

109. Wang J, Xue Y, Liu J, Hu M, Zhang H, Ren K, Wang Y, Ji J. (2020). Hierarchical capillary coating to biofunctionlize drug-eluting stent for improving endothelium regeneration. Research. 3. 1458090. (区,IF:11.0) 

108. Zhang F, Yang L, Hu C, Li L, Wang J, Luo R, Wang Y. (2020). Phosphorylcholine- and cation- bearing copolymer coating with superior antibiofilm and antithrombotic properties for blood-contacting devices. Journal of Materials Chemistry B. 8, 8433-8443.(二区,IF:7.6

107. Wu B, Jin L, Ding, K, Zhou, Y, Yang, L, Lei, YGuo, Y, Wang, Y.  (2020). Extracellular Matrix Coating Improves the biocompatibility of polymeric heart valves. Journal of Materials Chemistry B. 8(46), 10616-10629.(二区,IF:7.6

106. Yang L, Huang X, Deng L, Ma X, Jiang H, Ning Q, Liang Z, Lei Y, Wang Y. (2020). Pre-mounted dry TAVI valve with improved endothelialization potential using REDV-loaded PEGMA hydrogel hybrid pericardium. Journal of Materials Chemistry B. 8(13), 2689-2701.(二区,IF:7.6

105. Liu J, Wang J, Xue Y, Chen T, Huang D, Wang Y, Ren K, Wang Y, Fu G, Ji J. (2020). Biodegradable phosphorylcholine copolymer for cardiovascular stent coating. Journal of Materials Chemistry B. 8(24), 5361-5368.(二区,IF:7.6

104. Chen L, Zhuang W, Hu C, Yu T, Su X, Liang Z, Li G, Wang Y. (2020). pH and singlet oxygen dual-responsive GEM prodrug micelles for efficient combination therapy of chemotherapy and photodynamic therapy. Journal of Materials Chemistry B. 8(26), 5645-5654.(二区,IF:7.6

103. Hu C, Zhuang W, Yu T, Chen L, Liang Z, Li G, Wang Y. (2020). Multi-stimuli responsive polymeric prodrug micelles for combined chemotherapy and photodynamic therapy. Journal of Materials Chemistry B. 8(24), 5267-5279.(二区,IF:7.6

102. Kuang D, Lei Y, Yang L, Wang Y. (2020). Preclinical study of a self-expanding pulmonary valve for the treatment of pulmonary valve disease, Regenerative Biomaterials. 609-618.(一区,IF:5.8

101. Xu H, M9 B, Jiang J, Xiao S, Peng R, Zhuang W, Li, G, Wang, Y. (2020). Integrated prodrug micelles with two-photon bioimaging and pH-triggered drug delivery for cancer theranostics. Regenerative Biomaterials. 7(2), 171-180.(一区,IF:5.8

100.Yin A, Zhuang W, Liu G, Lan X, Tang Z, Deng Y, Wang Y. (2020). Performance of PEGylated chitosan and poly (L-lactic acid-co-ε-caprolactone) bilayer vascular grafts in a canine femoral artery model. Colloids and Surfaces B: Biointerfaces. 188, 110806. (二区,IF 6.0)

99. Jin L, He H, Yang F, Xu L, Guo G, Wang Y. (2020). Tough pNAGA hydrogel hybridized porcine pericardium for the pre-mounted TAVI valve with improved anti-tearing properties and hemocompatibility. Biomedical Materials. 15(6), 065013.(三区,IF:4.1

98. Lan X, Zhao Q, Zhang J, Lei Y, Wang Y. (2020). A combination of hydrogen bonding and chemical covalent crosslinking to fabricate a novel swim-bladder-derived dry heart valve material yields advantageous mechanical and biological properties. Biomedical Materials. 16(1), 015014.(三区,IF:4.1

97. Su X, Zhuang W, Yu T, He H, Ma B, Chen L, Yang L, Li G, Wang Y. (2020). ROS and GSH dual‐Responsive GEM prodrug micelles for ROS‐triggered fluorescence turn on bioimaging and cancer therapy. Advanced Materials Interfaces, 7(13). 2000294.(二区,IF:6.4

96. Hu Q, Zhou S, Hu X, Zhang H, Huang S, Wang Y. (2020). Systematic screening identifies a 2‐gene signature as a high‐potential prognostic marker of undifferentiated pleomorphic sarcoma/myxofibrosarcoma. Journal of Cellular and Molecular Medicine. 24(1), 1010-1021. (二区,IF:5.3) 

95. Long L, Wu C, Hu X, Wang Y. (2020). Biodegradable synthetic polymeric composite scaffold-based tissue engineering heart valve with minimally invasive transcatheter implantation. Polymers for Advanced Technologies. 31(11), 2422–2432.(三区,IF:3.4)

94. Kong Q, Ma B, Yu T, Hu C, Li G, Jiang Q, Wang Y. (2020). A two-photon AIE fluorophore as a photosensitizer for highly efficient mitochondria-targeted photodynamic therapy. New Journal of Chemistry. 44(22), 9355-9364.(三区,IF:3.9

93. Long L, Zhang J, Yang Z, Guo Y, Hu X, Wang Y. (2020). Transdermal delivery of peptide and protein drugs: strategies, advantages and disadvantages. Journal of Drug Delivery Science and Technology. 60, 102007.(三区,IF:5.0

92. Yin A, Lan X, Zhuang W, Tang Z, Li Y, Wang Y. (2020). PEGylated chitosan and PEGylated PLCL for blood vessel repair: An in vitro study. Journal of Biomaterials Applications. 34(6), 778-789.(三区,IF:2.7

91. Chen C, Xiong Y, Jiang W, Wang Y, Wang Z, Chen Y. (2020). Experimental and numerical simulation of biodegradable stents with different strut geometries. Cardiovascular Engineering and Technology. 11(1), 36-46.(三区,IF:2.3

90. Xu Y, Wang D, Kuang T, Wu W, Xu X, Jin D, Zhang H, Zhong S, Wang Y, Lou W. (2020). Nanomaterials augmented LDI-TOF-MS for pancreatic ductal adenocarcinoma diagnosis and classification. Journal of Clinical Oncology. Volume 38, Issue 15, suppl. e16761.(一区,IF:50.7

89.雷洋、胡雪丰、张婕妤、王云兵,组织工程方法在人工心脏瓣膜领域上的应用,生命科学,2020, 32(3): 288-298.

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88. Lu J, Zhuang W, Li L, Zhang B, Yang L, Liu D, Wang Y. (2019). Micelle-embedded layer-by-layer coating with catechol and phenylboronic acid for tunable drug loading, sustained release, mild tissue response, and selective cell fate for re-endothelialization. ACS Applied Materials & Interfaces, 11(10), 10337-10350.(一区,IF:10.4

87. Zhang B, Yao R, Li L, Wang Y, Luo R, Yang L, Wang Y. (2019). Green tea polyphenol induced Mg2+-rich multilayer conversion coating: toward enhanced corrosion resistance and promoted in situ endothelialization of AZ31 for potential cardiovascular applications. ACS Applied Materials & Interfaces, 11(44), 41165-41177.(一区,IF:10.4

86. Zhang F, Hu C, Kong Q, Luo R, Wang Y. (2019). Peptide-/Drug-directed self-Assembly of hybrid polyurethane hydrogels for wound healing. ACS Applied Materials & Interfaces, 11(40), 37147-37155.(一区,IF:10.4

85. Ma B, Zhuang W, Xu H, Li G, Wang Y. (2019). Hierarchical responsive nanoplatform with two-photon AIE imaging for efficient cancer theranostic. ACS Applied Materials & Interfaces, 11(50), 47259-47269.(一区,IF:10.4

84. Zhuang W, Yang L, Ma B, Kong Q, Li G, Wang Y, Tang B. (2019). Multifunctional two-photon AIE luminogens for highly mitochondria-specific bioimaging and efficient photodynamic therapy. ACS Applied Materials & Interfaces, 11(23), 20715-20724.(一区,IF:10.4

83. Zhuang W, Ma B, Hu J, Jiang J, Li G, Yang L, Wang Y. (2019). Two-photon AIE luminogen labeled multifunctional polymeric micelles for theranostics. Theranostics, 9(22), 6618-6630.(一区,IF:11.6

82. Wang J, Chen X, Xue Y, Hu M, Wang Y, Ren K, Ji J. (2019). Thermo-triggered ultrafast self-healing of microporous coating for on-demand encapsulation of biomacromolecules. Biomaterials, 192, 15-25.(一区,IF:15.3

81. Lu Y, Wang Y, Zhang J, Hu X, Yang Z, Guo Y, Wang Y. (2019). In-situ doping of a conductive hydrogel with low protein absorption and bacterial adhesion for electrical stimulation of chronic wounds. Acta Biomaterialia, 89, 217-226.(一区,IF:10.6

80. Ma B, Zhuang W, He H, Su X, Yu T, Hu J, Yang L, Li G, Wang Y. (2019). Two-photon AIE probe conjugated theranostic nanoparticles for tumor bioimaging and pH-sensitive drug delivery. Nano Research, 12, 1703-1712.(一区,IF:10.3

79. Hu C, Zhang F, Kong Q, Lu Y, Zhang B, Wu C, Luo R, Wang Y. (2019). Synergistic chemical and photodynamic antimicrobial therapy for enhanced wound healing mediated by multifunctional light-responsive nanoparticles. Biomacromolecules, 20(12), 4581-4592.(一区,IF:7.0

78. Zhang W, Wang Z, Xie C, Wang X, Luo F, Hong M, Zhou R, Ma C, Lin N, Zhang J, Hu X, Chan J, Wen F, Wang Y. (2019). Scaffold with Micro/Macro‐Architecture for Myocardial Alignment Engineering into Complex 3D Cell Patterns. Advanced Healthcare Materials, 8(22), 1901015 (一区,  IF:11.1)

77. Cheng Y, Zhang J, Wang Y, Li C, Lu Z, Hu X, Xu L. (2019). Deposition of catechol-functionalized chitosan and silver nanoparticles on biomedical titanium surfaces for antibacterial application. Materials Science and Engineering C, 98, 649-656. (二区,IF: 8.4

76. Zou M, Jin R, Hu Y, Zhang Y, Wang H, Liu G, Nie Y, Wang, Y. (2019). A thermo-sensitive, injectable and biodegradable in situ hydrogel as a potential formulation for uveitis treatment. Journal of Materials Chemistry B, 7(28), 4402-4412. (二区,IF:7.6

75. Hu J, Zhuang W, Ma B, Su X, Yang L, Li G, Wang Y. (2019). A two-photon fluorophore labeled multi-functional drug carrier for targeting cancer therapy, inflammation restraint and AIE active bioimaging. Journal of Materials Chemistry B, 7(24), 3894-3908. (二区,IF:7.6

74. Guo G, Jin W, Jin L, Chen L, Lei Y, Wang Y. (2019). Hydrogel hybrid porcine pericardium for the fabrication of a pre-mounted TAVI valve with improved biocompatibility. Journal of Materials Chemistry B, 7(9), 1427-1434.(二区,IF:7.6

73. Wang Y, Lu Y, Zhang J, Hu X, Yang Z, Guo Y, Wang Y. (2019). A synergistic antibacterial effect between terbium ions and reduced graphene oxide in a poly (vinyl alcohol)–alginate hydrogel for treating infected chronic wounds. Journal of Materials Chemistry B, 7(4), 538-547.(二区,IF:7.6

72. Zhang B, Yao R, Li L, Li M, Yang L, Liang Z, Luo R, Wang, Y. (2019). Bionic tea stain–like, all‐nanoparticle coating for biocompatible corrosion protection. Advanced Materials Interfaces, 6(20),1900899.(二区,IF:6.4

71. Yu D, Zhuang Z, Ren J, Hu X, Wang Z, Zhang J, Luo Y, Wang K, He R, Wang Y. (2019). Hyaluronic acid-curcumin conjugate suppresses the fibrotic functions of myofibroblasts from contractive joint by the PTGER2 demethylation. Regenerative Biomaterials. 6(5), 269-277.  (一区,IF: 5.8) 

70. Jin L, Guo G, Jin W, Lei Y, Wang Y. (2019). Cross-linking methacrylated porcine pericardium by radical polymerization confers enhanced extracellular matrix stability, reduced calcification, and mitigated immune response to bioprosthetic heart valves. ACS Biomaterials Science & Engineering, 5(4), 1822-1832. (二区,IF:5.4)

69. Zhang H, Shen X, Wang J, Huang N, Luo R, Zhang B,  Wang Y. (2019). Multistep Instead of One-Step: A Versatile and Multifunctional Coating Platform for Biocompatible Corrosion Protection. ACS Biomaterials Science & Engineering5(12), 6541-6556. (二区,IF:5.4)

68. He H, Zhuang W, Ma B, Su X, Yu T, Hu J, Wang Y. (2019). Oxidation-responsive and aggregation-induced emission polymeric micelles with two-photon excitation for cancer therapy and bioimaging. ACS Biomaterials Science & Engineering, 5(5), 2577-2586.(二区,IF:5.4

67. Yu T, Zhuang W, Su X, Ma B, Hu J, He H, Li G, Wang Y. (2019). Dual-Responsive Micelles with Aggregation-Induced Emission Feature and Two-Photon Aborsption for Accurate Drug Delivery and Bioimaging. Bioconjugate chemistry, 30(7), 2075-2087. (二区,IF:6.1)
66. Huang F, Xia T, Li J, Li C, Zhao Z, Lei W, Chen L, Liao Y, Xiao D, Peng Y, Wang Y, Liu X, Chen M. (2019). The bifunctional SDF‐1‐AnxA5 fusion protein protects cardiac function after myocardial infarction. Journal of cellular and molecular medicine. 23(11):7673–7684. (
二区,IF:5.3)

65. Lei Y, Yang L, Guo G, Wang Y. (2019). EGCG and enzymatic cross‐linking combined treatments for improving elastin stability and reducing calcification in bioprosthetic heart valves. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 107(5), 1551-1559.(三区,IF:3.4

64. Lei Y, Deng L, Tang Y, Ning Q, Lan X, Wang Y. (2019). Hybrid pericardium with VEGF‐loaded hyaluronic acid hydrogel coating to improve the biological properties of bioprosthetic heart valves. Macromolecular Bioscience, 19(6),1800390.(三区,IF:5.8

63. Lei Y, Ning Q, Tang Y, Wang Y. (2019). Exogenous hyaluronic acid and chondroitin sulfate crosslinking treatment for increasing the amount and stability of glycosaminoglycans in bioprosthetic heart valves. Journal of Materials Science: Materials in Medicine, 30(3), 38. (三区,IF:4.7

62. Lei Y, Ning Q, Xia Y, Wang Y. (2019). Enzyme-oxidative-polymerization method for improving glycosaminoglycans stability and reducing calcification in bioprosthetic heart valves. Biomedical Materials, 14(2):025012.(三区,IF:4.1

61.  Lei Y, Guo G, Jin W, Liu M, Wang Y. (2019). Riboflavin photo‐cross‐linking method for improving elastin stability and reducing calcification in bioprosthetic heart valves. Xenotransplantation, 26(2), e12481.(三区,IF:3.8

60. Zhang J, Jiang X, Wen X, Xu Q, Zeng H, Zhao Y, Liu M, Wang Z, Hu X, Wang Y. (2019). Bio-responsive smart polymers and biomedical applications. Journal of Physics: Materials, 2(3), 032004.IF: 5.8

59. Hu Y, Su X, Lei Y, Wang Y. (2019). A novel anti-calcification method for bioprosthetic heart valves using dopamine-modified alginate. Polymer Bulletin, 76(3), 1423-1434. (IF: 2.8)

58. Yang L, Li L, Jiang L, Pan J, Luo R, Wang Y. (2019). Micelle-embedded coating with ebselen for nitric oxide generation. Medical Gas Research, 9(4), 176-183. (IF: 1.7)

57. 杨立、罗日方、雷洋, 王云兵,微创介入全降解血管支架和心脏瓣膜国内外研发现状与研究前沿. 材料导报, 2019, 33(1): 40-47.

56 张婕妤、 胡雪丰、李高参、巨晓洁、褚良银、王云兵. 海洋源壳聚糖与海藻酸盐在生物医药领域的应用,生物医学工程学杂志, 2019, 36(1): 164-171.

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55. Guo G, Jin L, Jin W, Chen L, Lei Y, Wang Y. (2018). Radical polymerization-crosslinking method for improving extracellular matrix stability in bioprosthetic heart valves with reduced potential for calcification and inflammatory response. Acta Biomaterialia, 82, 44-55.(一IF:10.6

54. Ma B, Zhuang W, Wang Y, Luo R, Wang Y. (2018). pH-sensitive doxorubicin-conjugated prodrug micelles with charge-conversion for cancer therapy. Acta Biomaterialia, 70, 186-196.(一区,IF:10.6

53. Zhuang W, Xu Y, Li G, Hu J, Ma B, Yu T, Su X, Wang Y. (2018). Redox and pH dual-responsive polymeric micelles with aggregation-induced emission feature for cellular imaging and chemotherapy. ACS Applied Materials & Interfaces, 10(22), 18489-18498.(一区,IF:10.4

52. Xia Q, Yang L, Hu K, Li K, Xiang J, Liu G, Wang Y. (2018). Chromium cross-linking based immobilization of silver nanoparticle coating on leather surface with broad-spectrum antimicrobial activity and durability. ACS Applied Materials & Interfaces, 11(2), 2352-2363. (一区,IF:10.4

51. Luo R, Zhang J, Zhuang W, Deng L, Li L, Yu H, Wang J, Huang N, Wang Y. (2018). Multifunctional coatings that mimic the endothelium: surface bound active heparin nanoparticles with in situ generation of nitric oxide from nitrosothiols. Journal of Materials Chemistry B, 6(35), 5582-5595.(二区,IF:7.6

50. Xu Y, Li G, Zhuang W, Yu H, Hu Y, Wang Y. (2018). Micelles prepared from poly (N-isopropylacrylamide-co-tetraphenylethene acrylate)-b-poly [oligo (ethylene glycol) methacrylate] double hydrophilic block copolymer as hydrophilic drug carrier. Journal of Materials Chemistry B, 6(45), 7495-7502.(二区,IF:7.6

49. Zhang H, Xie L, Shen X, Shang T, Luo R, Li X, Wang J, Huang N, Wang Y. (2018). Catechol/polyethyleneimine conversion coating with enhanced corrosion protection of magnesium alloys: potential applications for vascular implants. Journal of Materials Chemistry B, 6(43), 6936-6949.(二区,IF:7.6

48. Xie Y, Lan X, Bao R, Lei Y, Cao Z, Yang M, Wang Y. (2018). High-performance porous polylactide stereocomplex crystallite scaffolds prepared by solution blending and salt leaching. Materials Science and Engineering: C, 90, 602-609.(一区,IF:8.4

47. Xu L, Liao Y, Li N, Li Y, Zhang J, Wang Y, Li C. (2018). Vancomycin-assisted green synthesis of reduced graphene oxide for antimicrobial applications. Journal of colloid and interface science, 514, 733-739. (一区, IF:10.0)

46. Chen J, Hu M, Zhang H, Li B, Chang H, Ren K, Wang Y, Ji J. (2018). Improved Antithrombotic Function of Oriented Endothelial Cell Monolayer on Microgrooves. ACS Biomaterials Science & Engineering, 4(6), 1976-1985. (二区,IF:5.4)

45. Su X, Ma B, Hu J, Yu T, Zhuang W, Yang L, Li G, Wang Y. (2018). Dual-Responsive Doxorubicin-Conjugated Polymeric Micelles with Aggregation-Induced Emission Active Bioimaging and Charge Conversion for Cancer Therapy. Bioconjugate chemistry, 29(12), 4050-4061. (二区,IF:6.0)

44. Hu J, Zhuang W, Ma B, Su X, Yu T, Li G, Hu Y, Wang Y. (2018). Redox-Responsive Biomimetic Polymeric Micelle for Simultaneous Anticancer Drug Delivery and Aggregation-Induced Emission Active Imaging. Bioconjugate chemistry, 29(6), 1897-1910. (二区,IF:6.0)

43. Lei Y, Yang L, Guo G, Wang Y. (2018). EGCG and enzymatic cross‐linking combined treatments for improving elastin stability and reducing calcification in bioprosthetic heart valves. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 107(5), 1551-1559. (三区, IF:3.4)

42. Jin W, Guo G, Chen L, Lei Y, Wang Y. (2018). Elastin Stabilization Through Polyphenol and Ferric Chloride Combined Treatment for the Enhancement of Bioprosthetic Heart Valve Anticalcification. Artificial organs, 42(11), 1062-1069. (三区, IF: 2.7)

41. Zhuang W, Ma B, Liu G, Li G, Wang Y. (2018). TPE‐conjugated biomimetic and biodegradable polymeric micelle for AIE active cell imaging and cancer therapy. Journal of Applied Polymer Science, 135(1), 45651. (三区, IF: 3.1) 

40. Lei Y, Xia Y, Wang Y. (2018). The tropoelastin and lysyl oxidase treatments increased the content of insoluble elastin in bioprosthetic heart valves. Journal of Biomaterials Applications, 33(5), 637-646.(三区,IF: 3.1

39. Kong Q, Zhuang W, Li G, Jiang Q, Wang Y. (2018). Cation–anion interaction-directed formation of functional vesicles and their biological application for nucleus-specific imaging. New Journal of Chemistry, 42(11), 9187-9192. (三区,IF: 3.9)

38. Xu Y, Li G, Hu Y, Wang Y. (2018). Synthesis of Poly (N‐isopropylacrylamide)‐Block‐Poly (tert‐Butyl Methacrylate) Block Copolymer by Visible Light–Induced Metal‐Free Atom Transfer Polymerization. Macromolecular Chemistry and Physics, 219(17), 1800192. (三区, IF: 3.0)

37. Zhang K, Zhang J, Chen K, Hu X, Wang Y, Yang X, Fan Y. (2018). In vitro and in vivo assessment of nanostructured porous biphasic calcium phosphate ceramics for promoting osteogenesis in an osteoporotic environment. RSC Advances, 8(26), 14646-14653. (三区,IF:4.0

36. Lei Y, Jin W, Luo R, Li G, Guo G, Wang Y. (2018). Bioprosthetic heart valves’ structural integrity improvement through exogenous amino donor treatments. Journal of Materials Research, 33(17), 2576-2585. (IF:2.9)

35. Ning L, Kang E, Wang Y, Hu X, Xu L. (2018). Recent Developments in Controlled Release of Antibiotics. Current pharmaceutical design, 24(8), 911-925. (IF:3.36)

34.苏冠月, 余泓池, 黄雯雯, 王仁义, 胡亦清, 沈阳, 王云兵,刘肖珩. (2018). YAP 参与调控细胞上皮鄄间充质转化的研究进展. 45(7): 705-713. 

2017
33. Luo R, Yang L, Zhuang W, Yin A, Wang Y. (2017). Catechol-modified biomolecules in layer-by-layer assembly: a fishing net-like model to enhance stability and long-term performance. Journal of Controlled Release, 259, e116.
(一区,IF:11.5

32. Yin A, Li J, Mo X, Luo R, Zhang X, Wang Y. (2017). fabrication and characteration of coaxial electrospun multicomponent fibrous graft for vascular tissue engineering. Journal of Controlled Release, 259, e8. (一区,IF:11.5

31. Guo G, Tortorella M, Zhang B, Wang Y. (2017). Disassembly of micelle-like polyethylenimine nanocomplexes for siRNA delivery: High transfection efficiency and reduced toxicity achieved by simple reducible lipid modification. Journal of Colloid and Interface Science, 504, 633-644.(一区,IF:10.0

30. Yin A, Luo R, Li J, Mo X, Wang Y, Zhang X. (2017). Coaxial electrospinning multicomponent functional controlled-release vascular graft: Optimization of graft properties. Colloids and Surfaces B: Biointerfaces, 152, 432-439.(二区,IF:6.0

29. Li G, Xu Y, Kong Q, Zhuang W, Wang Y. (2017). Cation–anion interaction directed dual-mode switchable mechanochromic luminescence. Journal of Materials Chemistry C, 5(33), 8527-8534.(二区,IF:8.1

28. Zhuang W, Ma B, Liu G, Chen X, Wang Y. (2017). A fully absorbable biomimetic polymeric micelle loaded with cisplatin as drug carrier for cancer therapy. Regenerative biomaterials, 5(1), 1-8. (二区,IF: 5.8) 

27. Ma B, Zhuang W, Liu G, Wang Y. (2017). A biomimetic and pH-sensitive polymeric micelle as carrier for paclitaxel delivery. Regenerative biomaterials, 5(1), 15-24. (二区,IF: 5.8

26. Fan Y, Luo R, Han H, Weng Y, Wang H, Li J, Yang P, Wang Y, Huang N. (2017). Platelet adhesion and activation on chiral surfaces: the influence of protein adsorption. Langmuir, 33(39), 10402-10410. (二区, IF: 4.3)

25. Kong Q, Zhuang W, Li G, Xu Y, Jiang Q, Wang Y. (2017). High contrast stimuli-responsive luminescence switching of pyrene-1-carboxylic esters triggered by a crystal-to-crystal transition. New Journal of Chemistry, 41(22), 13784-13791.(三区,IF:3.9

24. Liu G, Chen X, Zhuang W, Nie Y, Zhang K, Yang L, Wang Y. (2017). Comparison of biomimetic block copolymer micelles as drug carriers for cancer therapy. Journal of Biomedical Nanotechnology, 13(11), 1500-1511.(三区,IF:3.6

23. Zhuang W, Ma B, Li G, Liu G, Wang Y. (2017). Redox-Sensitive Polymeric Micelles Based on Tetraphenylethylene-Conjugated Copolymer for Aggregation-Induced Emission Active Imaging and Drug Delivery. Journal of Biomedical Nanotechnology, 13(11), 1480-1489. (三区,IF:3.6

22. Li B, Ren K, Zhang H, Jia F, Wang J, Chang H, Wang Y, Ji J. (2017). Nanostructured Multilayer Films Assembled from Poly (dopamine)‐Coated Carbon Nanotubes for Controlling Cell Behavior. ChemNanoMat, 3(5), 319-327. (三区, IF 3.8)

2017年以前

21. Luo R, Wang X, Deng J, Zhang H, Maitz F, Yang L, Wang Y. (2016). Dopamine-assisted deposition of poly (ethylene imine) for efficient heparinization. Colloids and Surfaces B: Biointerfaces, 144, 90-98. (二区,IF:6.0

20. Luo R, Tang L, Xie L, Wang J, Huang N, Wang Y. (2016). Multifunctional mussel-inspired copolymerized epigallocatechin gallate (EGCG)/arginine coating: the potential as an ad-layer for vascular materials. Regenerative Biomaterials. 3(4):247-255.  (二区,IF: 5.8)

19. Yin A, Bowlin L, Luo R, Zhang X, Wang Y, Mo X. (2016). Electrospun silk fibroin/poly (L-lactide-ε-caplacton) graft with platelet-rich growth factor for inducing smooth muscle cell growth and infiltration. Regenerative Biomaterials, 3(4), 239-245. (二区,IF: 5.8)

18. Zhang H, Xie L, Deng J, Zhuang W, Luo R, Wang J, Huang N, Wang Y. (2016). Stability research on polydopamine and immobilized albumin on 316L stainless steel. Regenerative Biomaterials, 3(5), 277-284. (二区,IF: 5.8)

17. Yan Y, Chen N, Wang Y, Wang K. (2016). The application of antitumor drug-targeting models on liver cancer. Drug Delivery, 23(5), 1667-1675. (二区,IF: 6.8)

16. Liu G, Zhuang W, Chen X, Yin A, Nie Y, Wang Y. (2016). Drug carrier system self-assembled from biomimetic polyphosphorycholine and biodegradable polypeptide based diblock copolymers. Polymer, 100, 45-55. (二区, IF: 4.4)

15. Wang H, Xiong J, Liu G, Wang Y. (2016). A pH‐Sensitive Phospholipid Polymeric Prodrug Based on Branched Polyethylenimine for Intracellular Drug Delivery. Macromolecular Chemistry and Physics, 217(18), 2049-2055. (三区, IF: 3.0)

14. Li G, Xu Y, Zhuang W, Wang Y. (2016). Preparation of organic mechanochromic fluorophores with simple structures and promising mechanochromic luminescence properties. RSC Advances, 6(88), 84787-84793. (三区,IF:4.0

13. Li G, Yang K, Sun J, Wang Y. (2016). Highly specific probe for dual-emissive mitochondrial imaging based on a photostable and aqueous-soluble phosphonium fluorophore. RSC Advances, 6(96), 94085-94091. (三区,IF:4.0

12. Wang H, Liu G, Gao H, Wang Y. (2015). A pH-responsive drug delivery system with an aggregation-induced emission feature for cell imaging and intracellular drug delivery. Polymer Chemistry, 6(26), 4715-4718.

11. Liu G, Luo Q, Wang H, Zhuang W, Wang Y. (2015). In situ synthesis of multidentate PEGylated chitosan modified gold nanoparticles with good stability and biocompatibility. RSC Advances, 5(86), 70109-70116. 

10. Kleiner L, Wright J, Wang, Y. (2014). Evolution of implantable and insertable drug delivery systems. Journal of Controlled Release, 181, 1-10. (一区,IF:11.5

9. Wang Y, Zhang X. (2014). Vascular restoration therapy and bioresorbable vascular scaffold. Regenerative Biomaterials, 1(1): 49-55.  (二区,IF: 5.8)

8. Zhang K, Wang Y, Hillmyer M, Francis L. (2004). Processing and properties of porous poly(L-lactide)/bioactive glass composites. Biomaterials, 25(13), 2489-2500  

7. Hoss U, Shah R, Wang L, Wang Y, Mastrototaro J. (2003). Subcutaneous glucose sensor: experiences and future applications. Diabetes Technology Therapeutics, 5, 868-869.

6. Kumar A, Gross R, Wang Y, Hillmyer M. (2002). Recognition by lipases of ω-hydroxyl macroinitiators for diblock copolymer synthesis. Macromolecules35(20), 7606-7611.

5. Wang Y, Hillmyer M. (2001). Polyethylene‐poly (L‐lactide) diblock copolymers: synthesis and compatibilization of poly (L‐lactide)/polyethylene blends. Journal of Polymer Science Part A: Polymer Chemistry39(16), 2755-2766.

4. Wang Y, Hillmyer M. (2000). Synthesis of Polybutadiene− Polylactide Diblock Copolymers Using Aluminum Alkoxide Macroinitiators. Kinetics and Mechanism. Macromolecules33(20), 7395-7403.

3. Wang Y, Chen S, Huang J. (1999). Synthesis and Characterization of a Novel Macroinitiator of Poly (ethylene oxide) with a 4-Hydroxy-2, 2, 6, 6-tetramethylpiperidinyloxy End Group: Initiation of the Polymerization of Styrene by a “Living” Radical Mechanism. Macromolecules32(8), 2480-2483.

2. Wang Y, Huang J. (1998). Controlled radical copolymerization of styrene and the macromonomer of PEO with a methacryloyl end group. Macromolecules31(13), 4057-4060.

1. Wang Y, Du Q, Huang J. (1998). Grafting of poly (ethylene oxide) with Schiff's base end group onto chloromethylated polystyrene via Decker‐Forster reaction. Macromolecular rapid communications19(5), 247-250.

 

3.已申报并正式公开的中国专利:(排列顺序:专利名称;申请/专利号;公开/公告日)

2023

361.一种利用甲基丙烯酸异氰基乙酯交联的生物瓣膜材料、医疗器械及其方法和用途;CN202111363858.0;2023-04-04.

360.一种功能性生物心脏瓣膜材料及其制备方法和用途;CN202310068760.52023-03-21.

359.一种人工晶体及其制备方法;CN202310156644.92023-03-21.

358.一种共交联后双键交联生物瓣膜材料及其制备方法和应用;CN202211348509.62023-03-14.

357.一种基于微流控技术的显影载药微球及其制备方法和应用;CN202211412903.12023-02-24.

356.一种左心耳封堵器;CN202221639266.72023-02-14.

355.稳定夹持的穿刺夹钳;CN202123446569.52023-02-07.

354.一种共交联联合双键交联制备生物瓣膜材料的方法及生物瓣膜材料;CN202211274798.X2023-01-31.

353.一种可注射水凝胶/多酚miRNA载体缓释体系及其制备方法和用途;CN202211392451.52023-01-24.

352.一种长效缓释去铁胺的复合可注射心衰治疗水凝胶及其制备方法;CN202211282402.62023-01-10.

351.一种可降解封堵器及推送装置;CN202211296481.6;2023-01-10.

350.装载器及输送系统;CN202110764268.22023-01-06.

349.一种长效缓释丹酚酸B的可注射心衰治疗水凝胶及其制备方法; CN202211281337.52023-01-03.

2022

348.基于材料基因组方法的全降解血管支架材料筛选方法;CN202110698381.52022-12-23.

347.一种生物相容性抗炎水凝胶涂层及其制备方法;CN202211385325.72022-12-23.

346.一种亲水抗菌抗炎水凝胶薄膜及其制备方法与应用;CN202211130854.22022-12-20.

345.一种人工晶体材料及其制备方法和应用;CN202211388286.62022-12-06.

344.瓣膜夹合系统;CN202110628777.22022-12-06.

343.用于介入操作的器械固定装置;CN202123120595.92022-11-29.

342.自动同步的穿刺夹钳;CN202123452565.82022-11-29.

341.旋转同步的穿刺夹钳;CN202123451526.62022-11-29.

340.分离控制的穿刺夹钳;CN202123456169.22022-11-29.

339.介入器械的调弯手柄及介入系统;CN202123075289.82022-11-29.

338.心包提拉器以及心包介入装置;CN202120939814.72022-11-22.

337.一种封堵器;CN202210748586.42022-11-01.

336.一种电位低且检测范围宽的葡萄糖传感器及其制备方法;CN202210572547.32022-11-01.

335.一种抗凝血促血管修复的血液接触材料及其制备方法;CN202210258582.8 2022-10-04.

334.注射型凝胶组合物及其制备方法和应用;CN202210707785.02022-10-04.

333.一种可骨性愈合连接的皮下植入材料;CN202210701754.42022-09-27.

332.一种封堵器保护装置;CN202210748920.62022-09-20.

331.一种基于重组人源化胶原蛋白的可注射心衰治疗水凝胶及其制备方法;CN202210699300.82022-09-20.

330.一种功能化生物基质材料及其制备方法和应用;CN202180014565.32022-09-20.

329.热熔装置;CN202123075304.92022-09-13.

328.动作组件、动作装置及心包提拉器装置;CN202123060720.12022-09-13.

327.心包提拉器、心包提拉器装置及心包介入系统;CN202123061707.82022-09-13.

326.挂钩及封堵装置;CN202210481641.82022-09-09.

325.一种自愈合水凝胶多肽薄膜及其制备方法和应用;CN202210479933.82022-08-30.

324.一种改性交联生物瓣膜及其制备方法和用途;CN202210609109.X2022-08-30.

323.一种二芳基咪唑鎓盐及其抗菌用途;CN202210611556.92022-08-30.

322.一种用于治疗动脉粥样硬化的药物;CN202210676306.32022-08-30.

321.一种基于电子介质的高灵敏度葡萄糖传感器及其制备方法和使用方法;CN202210575103.52022-08-30.

320.具有心肌组织修复功能的抗心衰可注射水凝胶及其制备方法和应用;CN202210495091.52022-08-19.

319.一种用于心脏封堵器的可降解复合膜及其制备方法和应用;CN202210280463.2 2022-08-19.

318.一种高灵敏度葡萄糖传感器及其制备方法和应用;CN202210575085.02022-08-16.

317.一种高精度葡萄糖传感器及其制备方法;CN202210574834.82022-08-12.

316.一种用于心衰治疗的经导管可注射导电水凝胶及其制备方法;CN202210696115.32022-08-09.

315.一种用于颅骨修复的生物活性SBS材料及其制备方法和应用;CN202210620311.22022-08-05.

314.一种促心肌组织修复的全降解心脏封堵器涂层及其制备方法;CN202210226961.92022-07-29.

313.一种封堵器;CN202210348691.92022-07-29.

312.一种响应型水凝胶载药系统及其制备方法和用途;CN202210442032.12022-07-29.

311.一种双金属中心导电纳米材料葡萄糖传感及其制备方法和应用;CN202210572540.12022-07-22.

310.具有可调节倒钩的生物可降解左心耳封堵器;CN202122006902.42022-07-22.

309.具有心脏损伤修复功能的智能水凝胶及其制备方法和应用;CN202210555813.1 2022-07-22.

308.一种亲水润滑抗凝水凝胶薄膜及其制备方法和应用;CN202210480383.12022-07-15.

307.一种可降解封堵器抗凝血及快速内皮化涂层及其制备方法;CN202210456415.42022-07-15.

306.一种双键后交联提高生物瓣膜材料抗钙化及抗凝血性的方法;CN202210273141.52022-07-15.

305.一种共交联联合双键交联制备生物瓣膜材料的方法及生物瓣膜材料;CN202210272385.12022-07-15.

304.一种共交联生物瓣膜材料及其制备方法和应用;CN202210273134.52022-07-15.

303.一种双键后交联生物瓣膜材料及其制备和应用;CN202210273157.62022-07-15.

302.一种共交联后双键交联生物瓣膜材料及其制备方法和应用;CN202210273149.12022-07-15.

301.一种心脏封堵器用可降解复合膜及其制备方法和应用;CN202210281684.12022-06-24

300.可锁紧的无铆生物心房分流装置;CN202121392849.X2022-06-21

299.可降解分流器套装;CN202121395638.12022-06-21

298.一种抗凝促心肌组织修复的可降解封堵器及其制备方法;CN202210458430.22022-06-17

297.一种退变髓核修复可注射水凝胶及其用途;CN202210447092.22022-06-10

296.一种封堵器;CN202210178730.52022-06-07

295.具有抗炎及促修复功能的可注射水凝胶及其制备方法和在心脏修复中的应用;CN202180004209.32022-06-03

294.一种导电纳米材料葡萄糖传感材料及其制备方法和应用;CN202210085857.22022-04-22

293.分离控制的穿刺夹钳;CN202111660089.02022-04-22

292.旋转同步的穿刺夹钳;CN202111660088.62022-04-22

291.稳定夹持的穿刺夹钳;CN202111660080.X2022-04-22

290.一种可重复使用的葡萄糖传感器及其制备方法和应用;CN202210016256.62022-04-19

289.动作组件、动作装置、心包提拉器装置以及操作方法;CN202111485376.22022-04-05

288.心包提拉器、心包提拉器装置、心包介入系统及操作方法;CN202111485377.72022-04-05

287.心包介入装置;CN202120940457.62022-04-01

286.完全可降解左心耳封堵器;CN202121241102.42022-03-18

285.方便输送和回收的介入心脏封堵装置;CN202122037873.82022-03-04

284.一种用于纳米孔基因测序的磷脂双层膜及其制备方法;CN202111583288.62022-03-01

283.微环境响应的多功能可注射水凝胶及其制备方法和应用;CN202111265582.22022-03-01

282.一种心血管植介入材料/器械生物覆膜涂层及其制备方法;CN202111383830.32022-03-01

281.一种编织的单铆可降解植入器械;CN202111515149.X2022-02-11

280.一种带成型线保护的心血管封堵器输送装置;CN202111515176.72022-02-11

279.一种用于心血管封堵系统的输送装置;CN202122033389.82022-02-08

278.一种用于动脉粥样硬化治疗的大分子前药纳米载体及其制备方法;CN202111256673.X;2022-01-25 

2021

277.具有显影功能的封堵器及显影丝;CN202120634579.2;2021-12-28

276.无膜的部分可降解的左心耳封堵器;CN202121237165.2;2021-12-17

275.一种可降解封堵器涂层及其制备方法;CN202110988454.4;2021-12-10

274.生物补片施放装置;CN202120743098.5;2021-12-07

273.一种柔性导电抗菌材料及其制备方法;CN202111034061.6;2021-12-03

272.一种用于动脉粥样硬化治疗的载药体系及其制备方法;CN202010928197.0;2021-11-30

271.一种抗凝血抗钙化的人工心脏瓣膜材料及其制备方法与应用;CN202011143312.X;2021-11-30

270.一种具有优异长效抗凝血及抗菌抗污性能的生物医用涂层及其制备方法;CN202111027352.2;2021-11-30

269.一种酶改性的抗凝血瓣膜及其制备方法;CN202011523715.7;2021-11-23

268.一种柔性导电促血管生成材料及其制备方法;CN202111032557.X;2021-11-23

267.可指示行程的穿刺装置;CN202021975936.3;2021-11-23

266.一种生物组织的交联固定方法;CN202010278276.1;2021-11-23

265.一种用于防止血管移植术后狭窄的保护套管及其制备方法;CN202110947971.7;2021-11-19

264.心脏封堵装置及其制备方法;CN202011333760.6;2021-11-16

263.一种抗凝血的人工心脏瓣膜材料及其制备方法与应用;CN202011143306.4;2021-11-09

262.一种具有药物缓释及抗凝、抗钙化性能的血管支架涂层材料及其制备方法;CN202111026111.6;2021-11-09

261.一种可吸收封堵器;CN202110988437.0;2021-11-09

260.一种方便输送和回收的介入心脏封堵装置;CN202110987495.1;2021-11-02

259.一种带成型线保护的心血管封堵器输送装置;CN202110993184.6;2021-11-02

258.一种具有可调节倒钩的生物可降解左心耳封堵器;CN202110973288.0;2021-11-02

257.一种编织的单铆可降解植入器械;CN202110973290.8;2021-11-02

256.一种改性聚乳酸材料及其制备方法和应用;CN202110943910.3;2021-11-02

255.热定型冶具;CN202120740838.X2021-10-29

254.一种含氟多糖高分子化合物及其制备方法;CN202010316726.12021-10-22

253.一种功能化脱细胞基质生物材料及其制备方法和应用;CN202010096214.92021-10-15

252.一种长效超疏水抗凝生物瓣膜及其制备方法;CN202011524829.32021-10-15

251.一种基于超声波的股骨头坏死介入治疗装置;CN202110919344.22021-10-12

250.一种人工生物瓣膜处理方法;CN202110763039.92021-10-08

249.一种心包膜材料及其制备方法和用途;CN202010208263.72021-09-24

248.一种胶原水凝胶材料及其制备方法和用途;CN202010208233.62021-09-24

247.一种纳米孔基因测序用光交联磷脂双层膜及其制备方法;CN202110764795.32021-09-21

246.一种可降解分流器套装;CN202110690748.92021-09-21

245.一种人工晶状体用持久稳定的亲水抗污涂层及其制备方法;CN202010783385.92021-09-21

244.一种干燥胶原基生物材料的灭菌方法;CN202010040408.72021-09-21

243.一种可锁紧的无铆生物心房分流装置;CN202110690868.92021-09-21

242.一种用于纳米孔测序的磷脂双层膜及其制备方法;CN202110764783.02021-09-17

241.可调弯的介入器械;CN202021975009.12021-09-14

240.多向调弯的介入器械;CN202021978423.82021-09-14

239.定向调弯的介入器械;CN202021978215.82021-09-14

238.穿刺装置;CN202021974980.22021-09-14

237.多介质注射装置及其注射系统;CN202021976071.22021-09-14

236.注射装置以及注射系统;CN202021974935.72021-09-14

235.可控制鞘管调弯的手柄及介入器械;CN202021974989.32021-09-14

234.控制鞘管定向调弯的手柄及介入器械;CN202021975974.92021-09-14

233.心包提拉器以及心包介入装置;CN202110483760.22021-09-14

232.多腔道注射装置及其注射系统;CN202021978322.02021-09-14

231.介入器械的吸附头以及介入器械;CN202021976737.42021-09-10

230.双向调弯的手柄及介入器械;CN202021973736.42021-09-10

229.一种细胞外基质涂层增强高分子瓣膜生物相容性的方法;CN202010506677.82021-09-07

228.一种用于全降解血管支架的嵌段聚合物及制备方法;CN202110678348.62021-09-07

227.介入器械中管件的预装配模具;CN202021978254.82021-09-07

226.一种人工生物心脏瓣膜及其制备方法;CN202010972269.12021-08-31

225.一种仿生改性的瓣膜材料及其制备方法和应用;CN202011026335.22021-08-31

224.一种无膜的部分可降解的左心耳封堵器;CN202110619531.92021-08-24

223.一种完全可降解左心耳封堵器;CN202110618898.92021-08-24

222.一种具有垂直双凹结构的植入器械;CN202110618897.42021-08-24

221.一种高分子疏水涂层及其在制备疏水瓣膜中的应用;CN202010503319.12021-08-17

220.一种促进伤口愈合的金属/水凝胶复合敷料及其制备方法;CN201810020842.12021-08-10

219.基于EDC/NHS活化和重组人源胶原蛋白修饰的生物瓣膜材料及其制备方法;CN202010316933.72020-07-31

218.一种具有原位抗细胞粘附功能的光敏性生物可吸收聚合物及其制备方法;CN202110506093.52021-07-27

217.一种可快速光固化成型的光敏性液态全降解型低聚物及其制备方法;CN202110461278.92021-07-27

金属管材的热定型模具   CN202021976119.X   2021-07-20

216.一种生物抗污性能优异的人工晶状体涂层及其制备方法;CN202010782786.22021-07-20

215.一种加氢苯乙烯类热塑性弹性体在制备人工心脏瓣膜中的应用;CN202010045344.X2021-07-16

214.热熔装置;CN202021978348.52021-07-16

213.一种便于控制的肺动脉支架以及肺动脉瓣膜置换装置;CN202010827976.12021-07-13

212.一种可光固化3D打印成型的柔性可降解聚合物复合树脂及其制备方法;CN202110460775.72021-07-13

211.显影丝及具有显影功能的封堵器;CN202110335915.82021-07-09

210.一种非戊二醛交联生物材料及其制备方法;CN202110142345.02021-06-08

209.一种具有长效超疏水性能的生物抗污涂层及其制备方法;CN202110142155.92021-06-15

208.一种pH响应的双交联贻贝仿生粘附智能载药水凝胶及其制备方法和应用;CN202110090020.22021-05-28

207.一种抗钙化生物瓣膜材料及其制备方法;CN202010470622.62021-05-11

206.一种介入瓣膜输送系统的超润滑涂层及其制备方法;CN202010548698.62021-05-11

205.一种具有抗血栓抗钙化功能的瓣膜及其制备方法和应用;CN202010587270.22021-05-11

204.一种重组人源Ⅲ型胶原蛋白修饰的生物瓣膜材料及其制备方法;CN202010317451.32021-05-11

203.基于重组人源胶原蛋白的多功能支架涂层及其制备方法;CN202010452431.72021-05-11

202.一种混合电荷聚氨酯涂层材料及其制备方法与应用;CN202110096061.22021-05-07

201.一种酶改性的抗凝血瓣膜及其制备方法;CN202011523715.72021-05-04

200.一种便携式离子导入设备;CN202020532499.12021-04-27

199.一种局部离子导入设备;CN202020539188.82021-04-27

198.一种长效超疏水抗凝生物瓣膜及其制备方法;CN202011524829.32021-04-13

197.一种具有协同抗凝及抗钙化功能的瓣膜材料及其制备方法;CN202010541893.62021-03-30

196.一种抗凝血抗钙化生物材料及其制备方法;CN202010331255.12021-03-30

195.一种双锥型金纳米颗粒及其制备方法;CN202011352758.32021-03-30

194.一种用于体外膜肺氧合装置(ECMO)的长效抗凝抗菌涂层及其制备方法;CN202010144236.82021-03-30

193.一种用于柔性生物电子器件的材料及其制备方法;CN202010645199.92021-03-30

192.具有聚集诱导发光及双重敏感性的聚合物药物载体、载药胶束及其制备方法;CN201810430246.02021-03-30

191.一种表面电荷可转换的聚合物纳米药物载体及制备方法和应用;CN201810124303.22021-03-30

190.一种具有长效抗血栓性能的瓣膜材料及其制备方法;CN202010542260.72021-03-30

189.一种人工生物瓣膜及其制备方法;CN202010331262.12021-03-30

188.用于体外膜肺氧合(ECMO)的长效膜式氧合器中空纤维抗凝涂层及制备方法;CN202010640459.32021-03-30

187.具有垂直双凹结构的植入器械;CN202121237256.62022-03-18

186.一种提高力学及抗凝血性能的生物瓣膜交联方法;CN202011421499.52021-03-12

185.一种采用酶交联和茶多酚组合联用处理生物瓣膜的方法;CN201810949307.42021-03-12

184.一种人工生物瓣膜的方法;CN201811219774.82021-03-12

183.一种多孔硅纳米线及其制备方法;CN202011007261.82021-03-09

182.心脏封堵装置及其制备方法;CN202011333760.62021-02-05

181.基于EDC/NHS活化和重组人源胶原蛋白修饰的生物瓣膜材料及其制备方法;CN202010316933.72021-01-26

180.一种抗凝血抗钙化的人工心脏瓣膜材料及其制备方法与应用;CN202011143312.X2021-01-26

179.多向调弯的介入器械;CN202010947246.52021-01-22

178.介入器械;CN202010947369.92021-01-22

177.介入器械的吸附头以及介入器械;CN202010946663.82021-01-22

176.介入导管及其生产工艺;CN202010947301.02021-01-22

175.一种抗凝血的人工心脏瓣膜材料及其制备方法与应用;CN202011143306.42021-01-15

174.一种人工生物心脏瓣膜及其制备方法;CN202010972269.12021-01-15

173.一种医用隔离眼罩;CN202020358597.82021-01-15 

2020

172.一种仿生改性的瓣膜材料及其制备方法和应用;CN202011026335.22020-12-18

171.一种医用防雾面罩;CN202020344187.82020-12-11

170.一种可解脱栓塞弹簧圈系统;CN202020023048.52020-12-04

169.一种微流控芯片及其制备方法;CN202010345010.42020-12-01

168.一种可吸收带线锚钉及其制备方法;CN202010939487.52020-12-01

167.一种可快速复水的预装式生物心脏瓣膜及其制备方法;CN201811095787.92020-12-01

166.一种心脏瓣膜夹具;CN202010827970.42020-11-24

165.一种用于动脉粥样硬化诊疗的载药体系及其制备方法;CN202010928197.02020-11-20

164.一种内皮化生物心脏瓣膜及其制备方法;CN202010040644.92020-10-30

163.一种非戊二醛可预装干燥生物瓣膜材料及制备方法和应用;CN202010097281.22020-10-30

162.一种可预装干燥生物心脏瓣膜及其制备方法;CN201811096562.52020-10-30

161.一种温敏仿生韧带及其制备方法;CN202010653132.X2020-10-27

160.一种人工晶状体用持久稳定的亲水抗污涂层及其制备方法;CN202010783385.92020-10-20

159.一种便于控制的肺动脉支架以及肺动脉瓣膜置换装置;CN202010827976.12020-10-16

158.用于体外膜肺氧合(ECMO)的长效膜式氧合器中空纤维抗凝涂层及制备方法;CN202010640459.32020-10-13

157.一种柔性电化学葡萄糖传感器及其制备方法;CN201911333165.X2020-10-09

156.一种生物抗污性能优异的人工晶状体涂层及其制备方法;CN202010782786.22020-10-02

155.一种多层复合的仿生人工韧带及其制备方法;CN202010642500.02020-10-02

154.一种生物瓣膜及其处理方法;CN202010589353.52020-09-25

153.一种具有抗血栓抗钙化功能的瓣膜及其制备方法和应用;CN202010587270.22020-09-25

152.一种介入瓣膜输送系统的超润滑涂层及其制备方法;CN202010548698.62020-09-22

151.一种小尺寸经导管人工心脏瓣膜及其制备方法;CN202010526984.22020-09-22

150.一种能靶向线粒体的双光子荧光探针及其制备方法和应用;CN201910326748.32020-09-29

149.一种具有协同抗凝及抗钙化功能的瓣膜材料及其制备方法;CN202010541893.62020-09-15

148.一种用于柔性生物电子器件的材料及其制备方法;CN202010645199.92020-09-15

147.一种具有长效抗血栓性能的瓣膜材料及其制备方法;CN202010542260.72020-09-15

146.一种亲水复合网络叠层修饰的心脏瓣膜及其制备方法;CN201910480363.22020-09-08

145.一种生物组织的交联固定方法;CN202010278276.12020-09-04

144.抗炎纳米药物载体、其药物组合物及制备方法和应用;CN202010464905.X2020-09-01

143.一种高分子疏水涂层及其在制备疏水瓣膜中的应用;CN202010503319.12020-08-25

142.一种兼具抗凝血和抗钙化性能的生物瓣膜及其制备方法;CN202010466435.02020-08-25

141.基于重组人源胶原蛋白的多功能支架涂层及其制备方法;CN202010452431.72020-08-25

140.一种微流控芯片及其制备方法;CN202010345010.42020-08-11

139.一种抗钙化生物瓣膜材料及其制备方法;CN202010470622.62020-08-11

138.一种抗凝血抗钙化生物材料及其制备方法;CN202010331255.12020-08-04

137.一种细胞外基质涂层增强高分子瓣膜生物相容性的方法;CN202010506677.82020-07-28

136.一种自膨式介入瓣膜支架及其表面处理方法;CN202010469291.42020-07-28

135.一种带正电荷生物纤维止血抑菌材料及其制备方法和应用;CN202010187025.22020-07-28

134.一种用于SU-8光刻胶表面修饰的涂层及其制备方法;CN202010341782.02020-07-28

133.一种兼具抗凝血、抗炎、抗增生功能的涂层及其制备方法;CN201810732902.22020-07-28

132.一种炎症微环境响应的智能载药水凝胶及其制备方法和应用;CN202010490459.X2020-07-24

131.一种具有长期抗菌功能的水凝胶涂层及其制备方法;CN201810732892.22020-07-21

130.一种具有抗凝血和抗钙化功能的生物瓣膜及其制备方法;CN202010467248.42020-07-17

129.基于纳米材料辅助MALDI-TOF MS进行液体活检的方法;CN202010316901.72020-07-17

128.银纳米线材料作为MALDI-TOF MS基质在代谢产物检测中的应用;CN202010316936.02020-07-17

127.一种含有PEG接枝型壳聚糖的双层支架及其制备方法 CN201811198072.62020-07-17

126.银纳米球材料在MALDI-TOF MS检测小分子代谢产物中的应用;CN202010317503.72020-07-17

125.多孔硅纳米线联合MALDI-TOF MS在代谢小分子检测中的应用;CN202010316858.42020-07-14

124.氧化铁纳米材料联合MALDI-TOF MS在小分子代谢物检测中的应用;CN202010317493.72020-07-14

123.SiO2核/Au壳纳米材料作为基质在MALDI-TOF MS检测中的应用;CN202010316850.82020-07-14

122.一种医用口罩用熔喷无纺布的长效荷正电处理工艺;CN202010186493.82020-07-10

121.一种采用交联处理提高生物瓣膜稳定性的方法;CN201811148262.72020-07-07

120.一种具有长效抗菌性能的超亲水涂层及其制备方法;CN201810732803.42020-07-07

119.一种生物心脏瓣膜促进内皮化的方法;CN201811201583.92020-06-26

118.一种重组人源Ⅲ型胶原蛋白修饰的生物瓣膜材料及其制备方法;CN202010317451.32020-06-23

117.一种用于体外膜肺氧合装置(ECMO)的长效抗凝抗菌涂层及其制备方法;CN202010144236.82020-06-19

116.一种用于体外膜肺氧合装置(ECMO)长效抗凝血涂层及其制备方法;CN202010144224.52020-06-19

115.一种提高生物心脏瓣膜糖胺多糖稳定性的方法;CN201811201458.82020-06-12

114.聚合物药物载体、其载药组合物及制备方法和应用;CN201910337487.52020-06-12

113.一种医疗冰敷带;CN201920349810.62020-06-12

112.一种提高脱细胞基质生物相容性的交联方法;CN201811149232.82020-06-12

111.一种用于慢性创面治疗的导电水凝胶及其制备方法;CN201811170273.52020-06-09

110.一种干燥胶原基生物材料的灭菌方法;CN202010040408.72020-05-29

109.一种功能化脱细胞基质生物材料及其制备方法和应用;CN202010096214.92020-05-22

108.一种基于钛膜的离子导入装置;CN201920810701.X2020-05-19

107.一种内皮化生物心脏瓣膜及其制备方法;CN202010040644.92020-05-15

106.一种非戊二醛可预装干燥生物瓣膜材料及制备方法和应用;CN202010097281.22020-05-19

105.一种高强度可注射的人工晶状体材料及其制备方法和应用;CN201810244106.42020-05-01

104.减小压缩长度的瓣膜支架及具有该瓣膜支架的瓣膜置换装置;CN201710364702.12020-04-28

103.一种兼具抗炎及原位催化NO持续释放的双功能心血管涂层材料及其制备方法;CN201810731172.42020-04-21

102.一种具有催化NO长期稳定释放功能的超亲水涂层及其制备方法;CN201810732802.X2020-04-21

101.一种可解脱栓塞弹簧圈系统;CN202010012644.82020-04-10

100.一种多层钛膜;CN201920798909.42020-04-14

99.一种柔性电化学葡萄糖传感器及其制备方法;CN201911333165.X2020-03-17

98.一种仿生微纳叠层疏水生物瓣膜及其制备方法;CN201910480491.72020-03-10

97.一种含促进内皮化生长因子的干燥人工生物心脏瓣膜及其制备方法;CN201910405391.82020-03-10

96.一种镁基金属材料转化膜及其制备方法;CN201810732184.92020-03-10

95.一种含促进内皮化多肽的干燥人工生物心脏瓣膜及其制备方法;CN201910408742.02020-03-10

94.一种具有超亲水性能的多功能心血管涂层材料及其制备方法;CN201810731279.92020-03-10

93.一种兼具抗钙化与抗增生双功能的长效缓释心血管涂层材料及其制备方法;CN201810731158.42020-03-10

92.一种采用酶交联和茶多酚组合联用处理生物瓣膜的方法;CN201810949307.42020-02-28

91.一种鱼鳔生物瓣膜材料的制备及保存方法;CN201911080303.82020-02-07

90.双键聚合和酶抑制剂组合处理的生物瓣膜材料制备及保存方法;CN201911080305.72020-02-11

89.甘油醚和多酚组合处理的生物瓣膜材料制备及保存方法;CN201911080458.12020-01-21

88.一种干化的动物细胞外基质材料的制备方法;CN201811441852.92020-01-10 

2019

87.碳二亚胺和多酚组合处理的生物瓣膜材料制备及保存方法;CN201911080307.62019-12-27

86.使用安全的瓣膜支架以及具有该瓣膜支架的瓣膜置换装置;CN201710364207.02019-12-17

85.一种采用光交联处理生物瓣膜的方法;CN201811148250.42019-12-06

84.一种全预装干燥介入主动脉瓣膜材料及其制备方法;CN201910929933.12019-11-29

83.一种全预装干燥介入肺动脉瓣膜材料及其制备方法;CN201910929901.12019-11-26

82.一种提高生物瓣膜弹性蛋白稳定性的交联处理方法;CN201811128254.62019-11-12

81.一种用于感染性慢性创面治疗的稀土掺杂水凝胶及其制备方法;CN201811382190.22019-11-05

80.一种利用激光进行可降解支架表面改性的创新性方法;CN201910569728.92019-11-05

79.生物可吸收聚(L-丙交酯)骨架降解曲线的控制;CN201610524672.12019-09-10

78.一种含促进内皮化生长因子的干燥人工生物心脏瓣膜及其制备方法;CN201910405391.82019-08-09

77.一种亲水复合网络叠层修饰的心脏瓣膜及其制备方法;CN201910480363.22019-08-23

76.一种仿生微纳叠层疏水生物瓣膜及其制备方法;CN201910480491.72019-08-23

75.一种含促进内皮化多肽的干燥人工生物心脏瓣膜及其制备方法;CN201910408742.02019-08-09

74.一种提高生物材料结构稳定性能的方法及其生物材料;CN201810269441.X2019-08-23

73.V形可降解生物架;CN201821372309.32019-07-12

72.生物可降解支架;CN201821370953.72019-07-12

71.一种能靶向线粒体的双光子荧光探针及其制备方法和应用;CN201910326748.32019-07-05

70.聚合物药物载体、其载药组合物及制备方法和应用;CN201910337487.52019-06-14

69.一种生物心脏瓣膜促进内皮化的方法;CN201811201583.92019-06-04

68.一种人工生物瓣膜的方法;CN201811219774.82019-06-04

67.一种提高生物瓣膜弹性蛋白稳定性的交联处理方法;CN201811128254.62019-06-04

66.一种提高脱细胞基质生物相容性的交联方法;CN201811149232.82019-06-04

65.一种采用交联处理提高生物瓣膜稳定性的方法;CN201811148262.72019-06-04

64.一种提高生物心脏瓣膜糖胺多糖稳定性的方法;CN201811201458.82019-06-04

63.一种交联的人工生物瓣膜处理方法;CN201811162531.52019-05-31

62.一种可浸水快速展平的干燥生物心脏瓣膜及其制备方法;CN201910132729.72019-05-31

61.一种采用光交联处理生物瓣膜的方法;CN201811148250.42019-05-31

60.一种用于慢性创面治疗的导电水凝胶及其制备方法;CN201811170273.52019-04-02

59.空芯光纤传输式紫外激光微加工装置;CN201820544265.12019-03-15

58.一种用于感染性慢性创面治疗的稀土掺杂水凝胶及其制备方法;CN201811382190.22019-03-12

57.一种干化的动物细胞外基质材料的制备方法;CN201811441852.92019-03-01

56.一种可预装干燥生物心脏瓣膜及其制备方法;CN201811096562.52019-01-25

55.一种可快速吸水展平的干燥生物心脏瓣膜及其制备方法;CN201811095786.42019-01-11

54.一种可快速复水的预装式生物心脏瓣膜及其制备方法;CN201811095787.92019-01-11 

2018

53.一种镁基金属材料转化膜及其制备方法;CN201810732184.92018-12-21

52.生物梯形可降解支架;CN201810971047.02018-12-18

51.生物可吸收支架;CN201810979503.62018-12-18

50.一种可催化一氧化氮释放的抗凝血水凝胶涂层及其制备方法;CN201810732906.02018-12-11

49.一种兼具抗炎及原位催化NO持续释放的双功能心血管涂层材料及其制备方法;CN201810731172.42018-12-07

48.一种含有PEG接枝型壳聚糖的双层支架及其制备方法;CN201811198072.62018-11-30

47.一种具有长期抗菌功能的水凝胶涂层及其制备方法;CN201810732892.22018-11-16

46.一种具有长效超亲水性能的生物抗污涂层及其制备方法;CN201810732218.42018-11-16

45.一种具有长效抗菌性能的超亲水涂层及其制备方法;CN201810732803.42018-11-16

44.一种多药物可控装载及长效缓释的生物医用涂层材料及其制备方法;CN201810731171.X2018-11-16

43.一种提高生物材料抗钙化性能的处理方法及其生物材料;CN201810740322.82018-11-13

42.一种具有催化NO长期稳定释放功能的超亲水涂层及其制备方法;CN201810732802.X2018-11-13

41.一种具有超亲水性能的多功能心血管涂层材料及其制备方法;CN201810731279.92018-11-13

40.一种具有高耐腐蚀性和表面功能化的镁基金属转化涂层及其制备方法;CN201810731286.92018-11-13

39.一种兼具抗钙化与抗增生双功能的长效缓释心血管涂层材料及其制备方法;CN201810731158.42018-11-02

38.一种兼具抗凝血、抗炎、抗增生功能的涂层及其制备方法;CN201810732902.22018-10-23

37.一种高强度可注射的人工晶状体材料及其制备方法和应用;CN201810244106.42018-09-28

36.具有氧化还原响应和AIE效应的聚合物药物载体、载药胶束及其制备方法;CN201810430255.X2018-09-21

35.具有聚集诱导发光及双重敏感性的聚合物药物载体、载药胶束及其制备方法;CN201810430246.02018-09-21

34.一种具有“三明治”夹心结构的生物医用水凝胶涂层及其制备方法;CN201810732188.72018-09-07

33.一种表面电荷可转换的聚合物纳米药物载体及制备方法和应用;CN201810124303.22018-07-24

32.空芯光纤传输式紫外激光微加工装置及加工方法;CN201810343340.22018-07-13

31.一种促进伤口愈合的金属/水凝胶复合敷料及其制备方法;CN201810020842.12018-04-20

30.一种提高海藻酸盐中古洛糖醛酸单元含量的方法;CN201711268028.32018-04-06

29.一种组织工程支架用聚乳酸多孔材料及其制备方法;CN201710889404.42018-02-09 

2017

28.防周漏水凝胶材料及其制备方法;CN201710108203.62017-07-18

27.减小压缩长度的瓣膜支架及具有该瓣膜支架的瓣膜置换装置;CN201710364702.12017-10-17

26.使用安全的瓣膜支架以及具有该瓣膜支架的瓣膜置换装置;CN201710364207.02017-09-15

25.紫外交联防周漏膜材料及其制备方法;CN201710108193.62017-06-27

24.一种用于按压血管支架显影珠的压杆;CN201620771015.22017-04-12

23.用于将聚合物支架压接至球囊的方法;CN201610555187.02017-03-22

22.具有双荧光发射的线粒体荧光探针及其制备方法和应用;CN201610827552.92017-02-22

21.一种含有布洛芬的载紫杉醇胶束聚合物、制剂及制备方法;CN201610729243.82017-02-01

20.具有压致变色性质的季膦盐类化合物及其制备方法和应用;CN201610744399.32017-01-25 

2017年以前:

19.一种激光切割机夹具;CN201620775515.32016-12-21

18.生物可吸收聚(L-丙交酯)骨架降解曲线的控制;CN201610524672.12016-11-09

17.一种植入型医疗器械的手持式高频振动清洗器;CN201610176947.72016-07-13

16.用于将支架安装至球囊导管的方法;CN201510658643.X2016-02-03

15.含聚氨基酸和聚磷酸胆碱的药物载体及其制备方法和应用;CN201510777575.92016-01-06

14.使聚合物支架的分子量在灭菌后稳定的方法;CN201510564607.72015-12-23

13.用于外周动脉疾病的药物递送装置;CN201380074437.32015-11-04

12.使医疗装置均匀卷曲和扩张的方法;CN201380057836.92015-11-11

11.一种尺寸单分散性聚合物纳米囊泡及其制备方法和应用;CN201510046944.72015-06-03

10.使在加工聚(L-丙交酯)支架中断链和单体产生最小化的方法;CN201410820411.52015-04-01

9.通过注塑和吹塑制造聚合物内假体的方法和系统;CN201280031685.52014-03-05

8.生物可吸收聚(L-丙交酯)骨架降解曲线的控制;CN201280028649.32014-04-30

7.聚合物医疗装置的电子束后调节;CN201180071619.62014-03-05

6.使聚合物支架的分子量在灭菌后稳定的方法;CN201280029276.12014-03-05

5.用于聚合物支架的均匀卷曲和展开的方法;CN201280030038.22014-02-26

4.使在加工聚(L-丙交酯)支架中断链和单体产生最小化的方法;CN201180059932.82013-08-21

3.对聚合物支架的压接损害的降低;CN201180051032.92013-06-19

2.用于将支架安装至球囊导管的方法;CN201180021928.22013-03-27

1.降解速率可调的聚(L-丙交酯)支架的制造方法;CN201180017582.9;2013-01-23


4. 已获得正式授权的美国专利:

Granted US PatentsPatent Name, Number, and Granted Date:

127. Shape memory bioresorbable polymer peripheral scaffolds, 11,337,835, May 24, 2022

126. Method of increasing stent retention of bioabsorbable scaffolding with a sheath, 10,703,050, July 7, 2020

125. Shape memory bioresorbable polymer peripheral scaffolds, 10,500,076, December 10, 2019

124. Flow regulation valve for controlling inflation rate of a balloon deploying a scaffold, 10,441,448, October 15, 2019

123. Method of uniform crimping and expansion of medical devices, 10,307,277, June 4, 2019

122. Controlling moisture in and plasticization of bioresorbable polymer for melt processing, 10,213,949, February 26, 2019

121. Bioabsorbable stent and treatment that elicits time-varying host-material response, 10,166,129, January 1, 2019

120. Implantable medical devices fabricated from branched polymers, 9,931,431, April 3, 2018

119. Methods for crimping a polymeric stent scaffold onto a delivery balloon, 9,895,241, February 20, 2018

118. Biodegradable stent with adjustable degradation rate, 9,889,238, February 13, 2018

117. Method of increasing stent retention of bioabsorbable scaffolding with a sheath, 9,855,705, January 2, 2018

116. Method of making a poly(L-lactide) stent with tunable degradation rate, 9,844,612, December 19, 2017

115.Methods for crimping a polymeric stent onto a delivery balloon, 9,757,897, September 12, 2017

114. Modification of bioabsorbable stent to reduce thrombogenecity, 9,750,852, September 5, 2017

113. Implantable medical devices fabricated from branched polymers, 9,744,259, August 29, 2017

112. Method of uniform crimping and expansion of medical devices, 9,724,219, August 8, 2017

111.Magnesium alloy implants with controlled degradation, 9,713,542, July 25, 2017

110. Method of treating with poly(L-lactide) stent with tunable degradation rate, 9,687,594, June 27, 2017

109. Implantable medical devices fabricated from polymers with radiopaque groups, 9,682,178, June 20, 2017

108. Uniform crimping and deployment methods for polymer scaffold, 9,681,972, June 20, 2017

107. Methods for crimping a polymeric scaffold to a delivery balloon and achieving stable mechanical properties in the scaffold after crimping, 9,681,971, June 20, 2017

106. Shape memory bioresorbable polymer peripheral scaffolds, 9,668,894, June 6, 2017

105. Methods to increase fracture resistance of a drug-eluting medical device, 9,656,002, May 23, 2017

104. Implantable medical devices fabricated from polyurethanes with biodegradable hard and soft blocks and blends thereof, 9,649,412, May 16, 2017

103. Reducing crimping damage to a polymer scaffold, 9,642,729, May 9, 2017

102. Sheaths reducing recoil and loss of retention for polymer scaffolds crimped to balloons, 9,579,181, February 28, 2017

101. Bioabsorbable stent that modulates plaque geometric morphology and chemical composition, 9,572,692, February 21, 2017

100. Post electron beam conditioning of polymeric medical devices, 9,566,723, February 14, 2017

99. Stents with adhesion promoting layer, 9,554,926, January 31, 2017

98. Control of balloon inflation rate during deployment of scaffold, 9,517,151, December 13, 2016

97. Stent retained on a balloon catheter, 9,504,590, November 29, 2016

96. Drug delivery device for peripheral artery disease, 9,498,321, November 22, 2016

95. Modification of bioabsorbable stent to reduce thrombogenecity, 9,446,172, September 20, 2016

94. Method of crimping polymeric stent to a delivery balloon, 9,403,320, August 2, 2016

93. Magnesium alloy implants with controlled degradation, 9,333,099, May 10, 2016

92. Flow regulation valve for controlling inflation rate of a balloon deploying a scaffold, 9,289,319, March 22, 2016

91. Polymer scaffold with multi-pleated balloon, 9,283,100, March 15, 2016

90. Bioabsorbable scaffold with particles providing delayed acceleration of degradation, 9,283,097, March 15, 2016

89. Method to prevent stent damage caused by laser cutting, 9,278,485, March 8, 2016

88. Tube expansion processes for semicrystalline polymers to maximize fracture toughness, 9,278,477, March 8, 2016

87. Method to minimize molecular weight drop of poly(L-lactide) stent during processing, 9,278,470, March 8, 2016

86. Drug delivery device for peripheral artery disease, 9,277,983, March 8, 2016

85. Composite polymeric and metallic stent with radiopacity, 9,265,866,February 23, 2016

84. Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups, 9,259,515, Feb. 16, 2016

83. Poly(L-lactide) stent with tunable degradation rate, 9,248,218, Feb. 2, 2016

82. Analyte sensors and methods for making and using them, 9,237,865, January 19, 2016

81. Uniform crimping and deployment methods for polymer scaffold, 9,199,408, December 1, 2015

80. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles, 9,199,004, December 1, 2015

79. Polyester implantable medical device with controlled in vivo biodegradability, 9,186,440, November 17, 2015

78. Rubber toughened bioresorbable polymer peripheral scaffolds, 9,180,228, November 10, 2015

77. Controlling moisture in and plasticization of bioresorbable polymer for melt processing, 9,168,677, October 27, 2015

76. Methods for crimping a polymeric scaffold to a delivery balloon and achieving stable mechanical properties in the scaffold after crimping, 9,155,870, October 13, 2015

75. Polymer-bioceramic composite medical devices with bioceramic particles having grafted polymers, 9,144,487, September 29, 2015

74. Bioabsorbable stent with radiopaque layer and method of fabrication, 9,101,698, August 11, 2015

73. Reducing crimping damage to a polymer scaffold, 9,084,693, July 21, 2015

72. Polymer composite stent with polymer particles, 9,072,820, July 7, 2015

71. Sheaths reducing recoil and loss of retention for polymer scaffolds crimped to balloons, 9,072,590, July 7, 2015

70. Methods to improve adhesion of polymer coatings over stents, 9,061,091, June 23, 2015

69. Reducing crimping damage to a polymer scaffold, 9,044,352, June 2, 2015

68. Methods for crimping a polymeric stent onto a delivery balloon, 9,032,607, May 19, 2015

67. Method of making polymer-bioceramic medical devices from a suspension solution of bioceramic particles, 8,999,369, April 7, 2015

66. Stent formed from bioerodible metal-bioceramic composite, 8,998,978, April 7, 2015

65. Shape memory bioresorbable polymer peripheral scaffolds, 8,968,387, March 3, 2015

64. Methods of stabilizing molecular weight of polymer stents after sterilization, 8,966,868, March 3, 2015

63. Method of improving fracture toughness of implantable medical devices through annealing, 8,961,862, February 24, 2015

62. Methods for crimping a polymeric stent onto a delivery balloon, 8,904,619, December 9, 2014

61. Method to make poly(L-lactide) stent with tunable degradation rate, 8,889,823, November 18, 2014

60. Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing, 8,882,825, November 11, 2014

59. Stent with nucleating agent, 8,852,263, October 7, 2014

58. Methods for crimping a polymeric stent scaffold onto a delivery balloon, 8,844,113, September 30, 2014

57. Controlling moisture in and plasticization of bioresorbable polymer for melt processing, 8,841,412, September 23, 2014

56. Control of degradation profile of bioabsorbable poly(l-lactide) scaffold, 8,834,776, September 16, 2014

55. Tube expansion processes for semicrystalline polymers to maximize fracture toughness, 8,828,305, September 9, 2014

54. Polyester implantable medical device with controlled in vivo biodegradability, 8,802,126, August 12, 2014

53. Methods for crimping a polymeric stent onto a delivery balloon, 8,752,266, June 17, 2014

52. Methods for crimping a polymeric scaffold to a delivery balloon and achieving stable mechanical properties in the scaffold after crimping, 8,752,265, June 17, 2014

51. Method and system for manufacturing a polymer endoprosthesis by injection molding and blow molding, 8,747,728, June 10, 2014

50. Method for stent retention on a balloon catheter, 8,739,384, June 3, 2014

49. Bioabsorbable scaffold with particles providing delayed acceleration of degradation, 8,709,070, April 29, 2014

48. Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent, 8,703,038, April 22, 2014

47. Post electron beam conditioning of polymeric medical devices, 8,613,880, December 24, 2013

46. Methods to increase fracture resistance of a drug-eluting medical device, 8,597,716, December 3, 2013

45. Bioabsorbable scaffolds made from composites, 8,545,546, October 1, 2013

44. Reducing crimping damage to polymer scaffold, 8,539,663, September 24, 2013

43. Fabricating an implantable medical device from an amorphous or very low crystallinity polymer construct, 8,535,593, September 17, 2013

42. Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing, 8,529,617, September 10, 201

41. Method of making polymer-bioceramic composite implantable medical devices, 8,512,735, August 20, 2013

40. Implantable medical devices fabricated from polyurethanes with biodegradable hard and soft blocks and blends thereof, 8,501,290, August 6, 2013

39. Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent, 8,496,865, July 30, 201

38. Methods to improve adhesion of polymer coatings over stents, 8,486,482, July 16, 2013

37. Implantable medical devices fabricated from branched polymers, 8,486,135, July 16, 2013

36. Methods of forming polymer-bioceramic composite medical devices with bioceramic particles, 8,425,591, April 23, 2013

35. Method for fabricating a polymer stent with break-away links for enhanced stent retention, 8,414,638, April 9, 2013

34. Method of improving fracture toughness of implantable medical devices through annealing, 8,394,317, March 12, 2013

33. Bioabsorbable stent with layers having different degradation rates, 8,377,533, February 19, 2013

32. Method and apparatus to prevent stent damage caused by laser cutting, 8,373,090, February 12, 2013

31. Fabricating an implantable medical device from an amorphous or very low crystallinity polymer construct, 8,372,332, February 12, 2013

30. Polymer-and polymer blend-bioceramic composite implantable medical devices, 8,343,530, January 1, 2013

29. Improving fracture toughness of medical devices with a stereocomplex nucleating agent, 8,337,739, December 25, 2012

28. Implantable medical devices comprising poly[l-lactide-co-(3,6-dialkyl-1,4-dioxane-2,5-dione)], 8,323,678, December 4, 2012

27. Method of making Polymer-bioceramic composite implantable medical devices, 8,309,114, November 13, 2012

26. Polymer tube expansion apparatus to maximize fracture toughness, 8,303,296, November 6, 2012

25.  Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices, 8,293,260, October 23, 2012

24. Implantable medical devices fabricated from polymer blends with star-block copolymers, 8,262,723, September 11, 2012

23. Methods for crimping a polymeric stent onto a delivery balloon, 8,261,423, September 11, 2012

22. Method for fabricating a stent with nucleating agent, 8,252,215, August 28, 2012

21. Method to minimize molecular weight drop of poly(L-lactide) stent during processing, 8,207,240, June 26, 2012

20. Implantable medical devices with elastomeric block copolymer coatings, 8,202,528, June 19, 2012

19. Method of Fabricating Polymer blend-bioceramic composite implantable medical devices, 8,119,705, February 21, 2012

18. Implantable medical device comprising copolymer of L-lactide with improved fracture toughness, 8,119,704, February 21, 2012

17. Methods for improved stent retention, 8,062,465, November 22, 2011

16. Bioabsorbable stent with layers having different degradation rates, 8,057,876, November 15, 2011

15. Method and apparatus for stent retention on a balloon catheter, 8,046,897, November 1, 2011

14. Stents formed from polymer-bioceramic composite with radiopaque bioceramic particles, 8,043,367, October 25, 2011

13. Tube expansion process for semicrystalline polymers to maximize fracture toughness, 8,012,402, September 6, 2011

12. Fixture for mechanical analysis of a hollow tube, 8,006,568, August 30, 2011

11. Methods to improve adhesion of polymer coatings over stents, 7,998,524, August 16, 2011

10. Degradable polymeric implantable medical devices with a continuous phase and discrete phase, 7,964,210, June 21, 2011

9. Polymer-bioceramic composite implantable medical devices, 7,959,940, June 14, 2011

8. Implantable medical devices fabricated from block copolymers, 7,956,100, June 7, 2011

7. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles, 7,955,381, June 7, 2011

6. Stent formed from polymer-bioceramic composite with radiopaque bioceramic particles, 7,935,143, May 3, 2011

5. Degradable polymeric implantable medical devices with continuous phase and discrete phase, 7,923,022, April 12, 2011

4. Method to fabricate a stent having selected morphology to reduce restenosis, 7,901,452, March 8, 2011

3. Polymer blend-bioceramic composite implantable medical devices, 7,842,737, November 30, 2010

2. Implantable medical devices comprising semi-crystalline poly(ester-amide), 7,771,739, August 10, 2010

1. Fixture for mechanical analysis of a hollow tube, 7,770,467, August 10, 201