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张凡军 助理研究员,硕士生导师    


工学博士,四川大学生物医学工程学院/国家生物医学材料工程技术研究中心专职博士后。主要从事血液接触医疗器械/植入材料的表面抗感染/抗凝血性能的研究,特别是多种类型的聚电解质之间絮凝及表面吸附行为的研究,以及界面引发聚合水凝胶涂层的研究。近5年来,以第一或通讯作者在国际生物材料领域期刊发表高水平论文8篇,授权国家发明专利4项,正在转化2项。

 

产品开发研究:

1、国产ECMO(体外膜肺氧合)系统研发,主要负责抗凝涂层技术开发。2、医用手术缝合线抗菌涂层国产化的研究。3、可植入式眼内接触镜(ICL)国产化的研究,主要负责HEMA材料的合成。4、自膨式形状记忆聚氨酯海绵的研究。

 

发表论文

1,Liu Y#, Zhang F#, Long L, Li J, Liu Z, Hu C, Chen X, Zan X, Xu J, Wang Y. (2022). Dual-function Hydrogels with Sequential Release of GSK3β Inhibitor and VEGF Inhibit Inflammation and Promote Angiogenesis after Stroke.  Chemical Engineering Journal. 433,133671.

2,Zhang F#, Hu Q#, Wei Y, Meng W, Wang R, Liu J, Nie Y, Luo R, Wang Y, Shen B. (2022). Surface modification of titanium implants by pH-Responsive coating designed for Self-Adaptive antibacterial and promoted osseointegration. Chemical Engineering Journal. 435, 134802.

3,Wei Y, Liu J, Liu G, Gao S, Wu D, Yang L, Luo R, Zhang F*, Wang Y. (2022). Hemocompatibility Multi-in-One Hydrogel Coating with ROS-Triggered Inflammation Suppression and Anti-Infection Properties for Blood-Contacting Device. Biomacromolecules. 10.1021/acs.biomac.2c00815.

4,Fanjun Zhang, Cheng Hu, Li Yang, Kunpeng Liu, Yao Ge, Yuan Wei, Jingyu Wang, Rifang Luo* and Yunbing Wang*, A conformally adapted all-in-one hydrogel coating: Towards robust hemocompatibility and bactericidal activity. Journal of Materials Chemistry B, 2021, 9, 2697-2708.

5, Fanjun Zhang, Li Yang, Cheng Hu, Linhua Li, Rifang Luo* and Yunbing Wang*, Phosphorylcholine- and cation-bearing copolymer coating with superior antibiofilm and antithrombotic properties for blood-contacting devices, Journal of Materials Chemistry B, 2020, 8, 8433-8443.

6, Fanjun Zhang, Cheng Hu, Qunshou Kong, Rifang Luo* and Yunbing Wang*, Peptide-/Drug-Directed Self-Assembly of Hybrid Polyurethane Hydrogels for Wound Healing, ACS Applied Materials & Interfaces, 2019, 11, 37147−37155.

7, Fanjun Zhang, Rong Wang, Yuanyuan He, Weiwei Lin, Yuxi Li, Yiqi Shao, Jiehua Li, Mingming Ding, Feng Luo*, Hong Tan* and Qiang Fu,A biomimetic hierarchical structure with a hydrophilic surface and a hydrophobic subsurface constructed from waterborne polyurethanes containing a self-assembling peptide extender, Journal of Materials Chemistry B, 2018, 6, 4326-4337.

8, Kunpeng Liu#, Fanjun Zhang#, Yuan Wei, Qinsheng Hu, Qingfeng Luo, Chong Chen, Jingyu Wang, Li Yang*, Rifang Luo*, and Yunbing Wang, Dressing Blood-Contacting Materials by a Stable Hydrogel Coating with Embedded Antimicrobial Peptides for Robust Antibacterial and Antithrombus Properties, ACS Appl. Mater. Interfaces 2021, 13, 33, 38947–38958


个人联系信息:

邮箱:zhfanjun@163.com;微信:zhfanjun

地址:四川省成都市武侯区望江路29号四川大学滨江楼,610065