研究方向：
智能药物递送系统
教育经历:
2011-2015 四川大学 本科
2015-2017 四川大学 硕士
2017-2020 四川大学 博士
已发表论文：
1. Cheng Hu#, Weihua Zhuang#, Tao Yu, et al. Multi-stimuli responsive polymeric prodrug micelles for combined chemotherapy and photodynamic therapy. J. Mater. Chem. B. 2020, 8, 5267-5279
2. Xin Su#, Weihua Zhuang#, Tao Yu, et al. ROS and GSH Dual-Responsive GEM Prodrug Micelles for ROS-Triggered Fluorescence Turn on Bioimaging and Cancer Therapy. Adv. Mater. Interfaces, 2020, 2000294.
3. Liang Chen#, Weihua Zhuang#, Cheng Hu, et al. pH and singlet oxygen dual-responsive GEM prodrug micelles for efficient combination therapy of chemotherapy and photodynamic therapy. J Mater. Chem. B, 2020, 8, 5645-5654.
4. Boxuan Ma, Hong Xu, Weihua Zhuang, et al. Reactive Oxygen Species Responsive Theranostic Nanoplatform for Two-Photon Aggregation-Induced Emission Imaging and Therapy of Acute and Chronic Inflammation. ACS Nano, 2020, 14, 5, 5862–5873.
5. Hong Xu#, Boxuan Ma#, Weihua Zhuang*, et al. Integrated prodrug micelles with two-photon bioimaging and pH-triggered drug delivery for cancer theranostics. Regenerat.Biomater., 2019, 7, 171–180.
6. Boxuan Ma, Weihua Zhuang, Hong Xu, et al. Hierarchical Responsive Nanoplatform with Two-Photon Aggregation-Induced Emission Imaging for Efficient Cancer Theranostics. ACS Appl. Mater. Interfaces, 2019, 11, 50, 47259–47269.
7. Anlin Yin, Weihua Zhuang, Gongyan Liu, et al. Performance of PEGylated chitosan and poly (L-lactic acid-co-ε-caprolactone) bilayer vascular grafts in a canine femoral artery model. Colloids and Surfaces B: Biointerfaces, 2020, 110806.
8. Weihua Zhuang#, Boxuan Ma#, Jun Hu, et al. Two-photon AIE luminogen labeled multifunctional polymeric micelles for theranostics. Theranostics, 2019, 9 (22): 6618-6630.
9. Weihua Zhuang#, Li Yang#, Boxuan Ma, et al. Multifunctional two-photon AIE luminogens for highly mitochondria-specific bioimaging and efficient photodynamic therapy. ACS Appl. Mater. Interfaces, 2019, 11, 20715−20724.
10. Jun Hu#, Weihua Zhuang#, Boxuan Ma et al. Two-photon Fluorophore Labeled Multi-functional Drug Carrier for Targeting Cancer Therapy, Inflammation Restraint and AIE Active Bioimaging.J. Mater. Chem. B ., 2019, 7, 3894.
11. Haiyang He#, Weihua Zhuang#, Boxuan Ma et al. Oxidation-Responsive and Aggregation-Induced Emission Polymeric Micelles with Two-Photon Excitation for Cancer Therapy and Bioimaging. ACS Biomater. Sci. Eng., 2019, 5, 2577−2586.
12. Boxuan Ma#, Weihua Zhuang#, Haiyang He et al. Two-photon AIE probe conjugated theranostic nanoparticles for tumor bioimaging and pH-sensitive drug delivery.Nano Res ., 2019, doi.org/10.1007/s12274-019-2426-4.
13. Tao Yu#, Weihua Zhuang#, Xin Su et al. Dual-Responsive Micelles with Aggregation-Induced Emission Feature and Two-Photon Aborsption for Accurate Drug Delivery and Bioimaging. Bioconjugate Chem., 2019, 30, 2075−2087.
14. Jiang Lu, Weihua Zhuang, Linhua Li et al. Micelle-Embedded Layer-by-Layer Coating with Catechol and Phenylboronic Acid for Tunable Drug Loading, Sustained Release, Mild Tissue Response, and Selective Cell Fate for Reendothelialization. ACS Appl. Mater. Interfaces., 2019, 11, 10337−10350.
15. Anlin Yin, Xiaorong Lan, Weihua Zhuang et al. PEGylated chitosan and PEGylated PLCL for blood vessel repair: An in vitro study. J. Biomater. Appl., 2019, DOI: 10.1177/0885328219875937.
16. Xin Su, Boxuan Ma, Weihua Zhuang* et al. Dual-Responsive Doxorubicin-Conjugated Polymeric Micelles with Aggregation-Induced Emission Active Bioimaging and Charge Conversion for Cancer Therapy. Bioconjugate Chem., 2018, 29, 4050−4061.
17. Weihua Zhuang, Yangyang Xu, Gaocan Li et al. Redox and pH Dual-Responsive Polymeric Micelles with Aggregation-Induced Emission Feature for Cellular Imaging and Chemotherapy. ACS Appl. Mater. Interfaces., 2018, 10, 18489−18498.
18. Rifang Luo, Jiang Zhang, Weihua Zhuang et al. Multifunctional coatings that mimic the endothelium: surface bound active heparin nanoparticles with in situ generation of nitric oxide from nitrosothiols. J. Mater. Chem. B., 2018, 6, 5582-5595.
19. Jun Hu#, Weihua Zhuang#, Boxuan Ma et al. Redox-Responsive Biomimetic Polymeric Micelle for Simultaneous Anticancer Drug Delivery and Aggregation-Induced Emission Active Imaging. Bioconjugate Chem., 2018, 29, 1897−1910.
20. Boxuan Ma#, Weihua Zhuang#, Yanan Wang et al. pH-Sensitive Doxorubicin-Conjugated Prodrug Micelles with Charge-Conversion for Cancer Therapy. Acta Biomater., 2018, 70, 186–196.
21. Weihua Zhuang#, Boxuan Ma#, Gongyan Liu et al. A Fully Absorbable Biomimetic Polymeric Micelle Loaded with Cisplatin as Drug Carrier for Cancer Therapy. Regenerat.Biomater., 2018, 1–8.
22. Boxuan Ma#, Weihua Zhuang#, Gongyan Liu et al. A Biomimetic and pH-Sensitive Polymeric Micelle as Carrier for Paclitaxel Delivery. Regenerat. Biomater., 2018, 15–24.
23. Weihua Zhuang#, Boxuan Ma#, Gongyan Liu et al. TPE-conjugated biomimetic and biodegradable polymeric micelle for AIE active cell imaging and cancer therapy. J Appl. Polymer Sci., 2018, 45651 (1 of 9).
24. YangYang Xu, Gaocan Li, Weihua Zhuang et al. Micelles prepared from poly (Nisopropylacrylamide-co-tetraphenyletheneacrylate)-b-poly [oligo (ethylene glycol) methacrylate] double hydrophilic block copolymer as hydrophilic drug carrier. J. Mater. Chem. B, 2018, 6, 7495.
25. Qunshou Kong, Weihua Zhuang, Gaocan Li et al. Cation–Anion Interaction-Directed Formation of Functional Vesicles and Their Biological Application for Nucleus-Specific Imaging. New J. Chem., 2018, 42, 9187.
26. Qunshou Kong#, Weihua Zhuang#, Gaocan Li et al. High contrast stimuli-responsive luminescence switching of pyrene-1-carboxylic esters triggered by a crystal-to-crystal transition. New J. Chem., 2017, 41, 13784.
27. Weihua Zhuang#, Boxuan Ma#, Gongyan Liu et al. Redox-Sensitive Polymeric Micelles Based on Tetraphenylethylene-Conjugated Copolymer for Aggregation-Induced Emission Active Imaging and Drug Delivery. J. Biomed. Nanotechnol., 2017, 13, 1480-1489.
28. Gongyan Liu, Xiaobing Chen, Weihua Zhuang, Yu Nie, Kai Zhang, Li Yang, Yunbing Wang. Comparison of Biomimetic Block Copolymer Micelles as Drug Carriers for Cancer Therapy. J. Biomed. Nanotechnol., 2017, 13, 1500-1511.
29. Gaocan Li, Yangyang Xu, Qunshou Kong, Weihua Zhuang and Yunbing Wang. Cation–anion interaction directed dual-mode switchable mechanochromic luminescence. J. Mater. Chem. C, 2017, 5, 8527-8534.
30. Gaocan Li, Yangyang Xu, Weihua Zhuang et al. Preparation of Organic Mechanochromic Fluorophores with Simple Structures and PromisingMechanochromic Luminescence Properties. RSC Adv., 2016, 6, 84787.
31. Gongyan Liu#, Weihua Zhuang#, Xiaobing Chen et al. Drug Carrier System Self-assembled from Biomimetic Polyphosphorycholine and Biodegradable Polypeptide based Diblock Copolymers. Polymer, 2016, 100, 45-55.
32. Hao Zhang, Lingxia Xie, Jinchuan Deng, Weihua Zhuang, Rifang Luo, Jin Wang, Nan Huang and YunbingWang. Stability research on polydopamine and immobilized albumin on 316L stainless steel. Regenerat. Biomater., 2016, 277–284.
33. Gongyan Liu, Quanqing Luo, Haibo Wang, Weihua Zhuang and Yunbing Wang. In situ synthesis of multidentate PEGylated chitosan modified gold nanoparticles with good stability and biocompatibility. RSC Adv., 2015, 5, 70109.